Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 332 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07629323Enrolling by invitation
Spinal Pain Relief During Hiatal Hernia Surgery
This trial tests whether injecting pain medication directly into the spinal fluid during a minimally invasive stomach surgery (called fundoplication) helps reduce pain after the operation. Fundoplication is used to treat severe acid reflux.
Karlstad, Värmland CountyAges 18 years+ - NCT07629388Recruiting
Nerve block for pain after knee replacement surgery
This trial tests whether adding a nerve block (a numbing injection near the nerve) to the usual pain plan can better control pain after a total knee replacement. The goal is to help you recover with less pain and fewer side effects.
DijonAges 18 years+ - NCT06704451Recruiting
IL-33 and memory after major abdominal surgery
This study looks at whether a protein called IL-33 is linked to memory and thinking problems that can happen after major abdominal surgery. It may help doctors find patients at risk earlier.
Kunming, YunnanAges Any age - NCT05529940RecruitingPhase 3
FOLFIRINOX around surgery for resectable pancreatic cancer
This trial compares giving chemotherapy with FOLFIRINOX before and after surgery versus giving it mainly after surgery for people with resectable pancreatic duct cancer. It aims to improve outcomes by timing the treatment around the operation.
SeoulAges 19–80 - NCT07607990Recruiting
Rectal Indomethacin to Prevent Catheter Discomfort After Prostate Surgery
This study tests whether a special suppository (indomethacin, a pain-relieving medication) placed in the rectum can reduce bladder catheter discomfort after laparoscopic prostate removal surgery. If it works, it could help patients recover more comfortably.
Hangzhou, ZhejiangAges 18–80 - NCT07603622Recruiting
Physical activity before surgery and recovery
This study looks at how your physical activity before surgery affects your recovery and long-term health. Researchers will track activity levels to see if they predict complications or survival after your operation. This could help tailor care to each patient.
StockholmAges 18 years+ - NCT07595068Recruiting
Ultrasound for Sleep and Heart Function Before Heart Surgery
This trial tests a new treatment using focused ultrasound to help regulate your nervous system and improve sleep quality before heart surgery. The goal is to help reduce anxiety and improve how well you sleep during the time leading up to and after your cardiology procedure.
Huangshi, HubeiAges 18–79 - NCT05185739RecruitingPhase 2
Pembrolizumab and lenvatinib before liver surgery for resectable cancer
This trial tests whether giving pembrolizumab (an immune therapy) and lenvatinib (a targeted pill) before planned liver surgery can improve outcomes for people with certain types of operable hepatocellular carcinoma (HCC). It’s meant for tumors that can be removed with curative intent, but still carry a risk of coming back.
BirminghamAges 18 years+ - NCT07589348Recruiting
Brain Function After Gynecologic Surgery
This study measures whether women experience changes in thinking and memory after having gynecologic surgery (removal of uterus and/or ovaries). Researchers want to understand how anesthesia and surgery affect the brain and identify who might be at risk.
İzmit, KocaeliAges 18 years+ - NCT07586124RecruitingPhase 2
Immunotherapy plus antibody drug for advanced head and neck cancer
This trial tests a combination of two drugs (pucotenlimab and becotatug vedotin) given before surgery for advanced head and neck squamous cell carcinoma. The goal is to shrink tumors and improve outcomes when combined with surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07576335RecruitingPhase 2
Prehabilitation and rehabilitation for prostate cancer surgery
This study tests a program that combines exercise, nutrition, and mental preparation before and after prostate removal surgery. The goal is to help you recover faster and keep better urinary and sexual function.
Sydney, New South WalesAges 18 years+ - NCT07571551RecruitingPhase 2
Immunotherapy and targeted drug treatment for kidney cancer
This trial tests a combination of immunotherapy and targeted drugs (called IO/TKI) given before and after surgery for clear cell renal cell carcinoma (a type of kidney cancer). The goal is to shrink tumors and improve survival outcomes.
Nanjing, JiangsuAges 18–80 - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60 - NCT07571473Recruiting
Monitoring stress during abdominal hysterectomy surgery
This study tests a new monitoring system called CoreSys that tracks your body's stress response during abdominal hysterectomy (surgical removal of the uterus). The goal is to help doctors better manage pain and stress during your operation.
Rosario, Santa Fe ProvinceAges 18–70 - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT06467617RecruitingPhase 2
Immunotherapy and chemo before and after lung cancer surgery
This trial tests a combination of an immunotherapy drug (adebrelimab) plus chemotherapy and another drug (recaticimab) before and after surgery for people with stage II or III lung cancer that can be removed. The goal is to see if this approach helps shrink tumors and improves outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT07568158Recruiting
How Anesthesia Nurses Handle Multiple Tasks During Surgery
This study looks at how anesthesia nurses manage their workload during different stages of surgery. Researchers will observe and measure how busy nurses feel while they care for patients under anesthesia, which could help improve training and safety in operating rooms.
Barcelona, CataloniaAges 18 years+ - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT07554846RecruitingPhase 3
Comparing immunotherapy before, during, or after surgery for early-stage lung cancer
This trial compares giving immunotherapy at different times around surgery for stage II-IIIA non-small cell lung cancer. The goal is to find the best time to use this treatment to improve outcomes.
ShanghaiAges 18–75 - NCT07558681Recruiting
Antibiotic dosing during liver and pancreas surgery
This study checks if the standard dose of an antibiotic (piperacillin/tazobactam) reaches effective levels in the blood during major liver or pancreas surgery. The goal is to improve infection prevention after surgery.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT07545538Enrolling by invitation
Carbohydrate Drink Before Surgery to Help Kids Recover
This study tests whether drinking a special carbohydrate solution before surgery helps children's bodies handle the stress of the operation better and recover more smoothly. The drink may reduce complications related to blood sugar control after surgery.
Yogyakarta, Special Region of YogyakartaAges 2–16 - NCT07537491Recruiting
AI tool to predict surgery outcomes in colorectal cancer
This study uses artificial intelligence to analyze tissue samples from your colorectal cancer surgery to help predict how you'll recover and what your long-term outlook might be. Researchers will examine your tumor tissue under a microscope to build a computer model that could help doctors personalize your care plan.
Brandenburg an der HavelAges 18 years+ - NCT07537205Enrolling by invitation
Nurse-led preparation program for liver cancer surgery
This study tests whether a personalized preparation program led by nurses before liver cancer surgery helps patients recover better and have fewer complications. The program is designed specifically for people scheduled to have part of their liver removed.
Shanghai, XuhuiAges 18–84
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 332 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.