Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04911816RecruitingPhase 1/Phase 2
Pre-surgery chemo plus oral hydroxychloroquine for pancreatic cancer
This trial studies giving chemo and hydroxychloroquine before surgery for resectable pancreatic cancer. The goal is to shrink the tumor and improve the chances of successful removal.
Morgantown, West VirginiaAges 18 years+ - NCT07186634RecruitingPhase 4
Surgery recovery medicine platform trial
This trial tests different medicines to improve recovery after surgery. It includes adults having surgery that lasts at least 2 hours and requires an overnight hospital stay.
Melbourne, VictoriaAges 18 years+ - NCT07263919RecruitingPhase 2
Chemo plus cadonilimab before surgery for esophageal cancer
This trial tests adding cadonilimab to standard chemotherapy before surgery for esophageal cancer that can be removed. It aims to see if this combination helps shrink the tumor and improve outcomes.
Xi'anAges 18–75 - NCT06824935Enrolling by invitation
Cataract surgery anesthesia needs study
This study looks at how much anesthesia is needed during outpatient cataract surgery. It may help find the right approach for your comfort and safety.
IstanbulAges 18 years+ - NCT06857331Recruiting
Numbing block for pain after liver transplant
This trial tests a special numbing injection (erector spinae plane block) to help control pain after liver transplant surgery. It may be a good option if you have severe liver disease and need a transplant.
KyivAges Any age - NCT07301307Recruiting
Blood pressure and fluid management during surgery
This trial tests a new tool that helps doctors manage fluids and blood pressure during surgery. It uses a special index (HPI) and computer-assisted fluid management to keep your blood pressure stable, which may reduce complications.
Athens, AtticaAges 18 years+ - NCT03125980RecruitingPhase 3
Chemo timing before vs after colon cancer surgery
This Phase 3 study compares two schedules of a colon cancer chemo combination: starting before surgery or starting after surgery. It aims to see which timing helps people live longer and lowers cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT06715709Enrolling by invitationPhase 4
How many doses of dexamethasone before knee replacement?
This trial compares different numbers of doses of dexamethasone (a steroid that reduces inflammation) given around the time of knee replacement surgery. It aims to find the best balance of pain control and side effects.
Rochester, MinnesotaAges 18 years+ - NCT06921668Recruiting
Energy use before and after esophagus surgery
This study measures how your body uses energy before and after scheduled esophagus removal surgery to understand recovery needs. It may help doctors provide better nutritional support during your hospital stay.
AmiensAges 18 years+ - NCT06890221Recruiting
Nutrition therapy before and after breast cancer surgery
This trial tests if a special nutrition drink before and after mastectomy can help breast cancer patients recover better. It uses a body measurement called bioimpedance phase angle to see how nutrition affects your cells and healing.
Petaling Jaya, Kuala LumpurAges 18 years+ - NCT06909071Recruiting
Smart insulin pump for blood sugar control after brain surgery
This trial tests a smart insulin pump (hybrid closed-loop system) to control high blood sugar after brain surgery for bleeding strokes. It's for people with type 2 diabetes who are stable enough to leave the intensive care unit and are getting tube feedings.
Taiyuan, ShanxiAges 18–75 - NCT06907758Recruiting
How organ donor care before surgery affects kidney transplant success
This study looks at whether special care given to brain-dead organ donors before their kidneys are removed helps the kidneys work better after they are transplanted into recipients. It reviews data from transplants done at Strasbourg University Hospital between 2018 and 2023.
StrasbourgAges 18 years+ - NCT06770179Enrolling by invitation
Lung breathing maneuver for kids during surgery
This study tests a special breathing maneuver (ultrasound-guided lung recruitment) during surgery to see if it helps prevent small areas of lung collapse in children. It may help kids with longer surgeries keep their lungs open and working better afterward.
IstanbulAges 1–14 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06776640Recruiting
Vitamin D3 before dental implant surgery for better bone bonding
This trial tests whether taking vitamin D3 pills before and after dental implant surgery helps the implant bond better with the bone. It is for people who have low vitamin D levels and are already scheduled for an implant.
Nantes, NantesAges 18 years+ - NCT07727681RecruitingPhase 4
Statins to Prevent Atrial Fibrillation After Lung Surgery
This trial tests whether taking a statin before and after lung surgery can prevent a common heart rhythm problem called atrial fibrillation (AFib). If you are 60 or older and having a lung segment or lobe removed, this study may help you avoid AFib after your operation.
BeijingAges 60 years+ - NCT06947655Recruiting
Tourniquet types for knee replacement surgery
This study compares different types of tourniquets (tight cuffs) used during knee replacement surgery to see how they affect blood loss and how satisfied surgeons are with them.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07287280Recruiting
Predicting surgery complications in gynecologic cancer
This study is comparing two different tools that doctors use to predict complications from gynecologic cancer surgery. The goal is to see which tool works better for planned (non-emergency) surgeries.
BangkokAges 18 years+ - NCT07571473Recruiting
Monitoring stress during abdominal hysterectomy surgery
This study tests a new monitoring system called CoreSys that tracks your body's stress response during abdominal hysterectomy (surgical removal of the uterus). The goal is to help doctors better manage pain and stress during your operation.
Rosario, Santa Fe ProvinceAges 18–70 - NCT07328958Recruiting
Ciprofol dosing for blood pressure in elderly abdominal surgery patients
This study tests if giving the sedative ciprofol in carefully adjusted doses can prevent low blood pressure during and after laparoscopic belly surgery in older adults. It may help your surgical team keep your blood pressure stable.
Guangzhou, GuangdongAges 65 years+ - NCT07699016Recruiting
Hemostatic agent use in heart and blood vessel surgery
This trial surveys surgeons about how they use hemostatic agents (medications that stop bleeding during surgery). It aims to understand current practices and improve patient safety.
Milan, MIAges 18 years+ - NCT07621120Recruiting
Wearable Device to Predict Surgery Risk in Older Adults
This study uses a wristwatch-like device to measure your movement and body functions before and after surgery to help predict which older patients might have complications. The goal is to improve safety planning for people 65 and older having surgery.
Beijing, Beijing MunicipalityAges 65 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 336 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.