Clinical trials
Peripheral Arterial Disease clinical trials
Below are recruiting peripheral arterial disease clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07313410Recruiting
Near-infrared light study for better understanding of PAD
This study uses near-infrared light to learn more about peripheral artery disease (PAD) in adults. It aims to help doctors better understand how PAD affects the body.
Arlington, TexasAges 18 years+ - NCT07318155RecruitingPhase 2
Study of SRSD107 for chronic heart or leg artery disease
This study tests a new medicine called SRSD107 for people with long-term blockages in heart or leg arteries. It aims to see if the drug can help prevent clots safely.
BeijingAges 18–75 - NCT07322913Recruiting
Study of Intervascular blood vessel grafts and patches
This study is collecting information from patients who have already had surgery to repair or replace blood vessels using Intervascular grafts or patches. Researchers will look at past medical records to see how well these devices work over time.
Hershey, PennsylvaniaAges 18 years+ - NCT04800276Recruiting
Exercise program for leg artery disease
This trial tests a supervised exercise program for people with leg pain when walking caused by narrowed leg arteries. The goal is to see if exercise can improve walking ability and quality of life.
Le MansAges 18 years+ - NCT07352800RecruitingPhase 2
Study of APAC for peripheral artery disease and severe leg ischemia
This trial tests a new drug called APAC to see if it safely prevents blood clots and improves blood flow in people with narrowed leg arteries. It may help those with severe symptoms like pain at rest or non-healing wounds, or those with claudication (leg pain when walking).
HelsinkiAges Up to 85 years - NCT07353905Recruiting
Ultrasound guidance for leg artery treatment
This trial tests whether using a special ultrasound probe inside the artery (intravascular ultrasound) helps doctors better treat blocked leg arteries. It may lead to more effective procedures for patients with leg pain or wounds due to poor blood flow.
Dallas, TexasAges 18 years+ - NCT07374601Recruiting
Testing Super-Resolution Ultrasound for Peripheral Artery Disease
This study tests a new ultrasound technique that creates clearer images of blood vessels. It may help doctors better diagnose and understand peripheral artery disease, which affects blood flow to the legs.
Beijing, Beijing MunicipalityAges 18–100 - NCT01904851Recruiting
Registry for leg artery procedures and their outcomes
This study collects information about people who had a procedure to improve blood flow in certain leg arteries. It helps researchers understand which treatments work best and what outcomes to expect.
Little Rock, ArkansasAges Any age - NCT02748226Recruiting
Study of artery procedures for leg artery disease outcomes
This study looks at results of a minimally invasive procedure done inside blood vessels (endovascular therapy) for people with painful or worsening leg artery disease. It uses both past (retrospective) and future (prospective) patient information to better understand outcomes.
SeoulAges 20 years+ - NCT03203239Recruiting
Red light treatment for circulation problems in leg arteries
This study tests whether a red-light therapy can improve symptoms or function in people with peripheral artery disease (poor blood flow to the legs). You may qualify if your leg circulation test is abnormal and you can safely take part in the study.
Milwaukee, WisconsinAges 18–85 - NCT07427108Recruiting
Road map vs. ultrasound for retrograde leg angioplasty
This trial compares two imaging methods (road map vs. ultrasound) to guide a needle puncture from the ankle area during angioplasty for blocked leg arteries. It aims to see which method is safer and more effective for patients with severe leg wounds or ulcers that need this retrograde approach.
SohagAges 18 years+ - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT07497360Recruiting
Telehealth vs. in-person sit-stand test for PAD patients
This study compares doing a 30-second sit-stand test at home via video call versus in a clinic. The goal is to see if remote testing works as well as in-person for people with peripheral artery disease (PAD). This could help you avoid extra trips to the clinic.
Izmir, BalçovaAges 18–65 - NCT07500610Recruiting
How inflammation affects heart and mobility in PAD
This study looks at how inflammation affects people with peripheral artery disease (PAD), and how it relates to heart health and walking ability. The goal is to understand these connections better, which could help doctors treat PAD more effectively.
Vancouver, British ColumbiaAges 19 years+ - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+ - NCT07613840Recruiting
Personalized Blood Clot Prevention After Leg Artery Surgery
This study tests a personalized approach to prevent blood clots in patients who have had surgery to repair blocked arteries in their legs. Researchers want to find the best blood-thinning medication for each individual to reduce serious complications while keeping you safe.
Boston, MassachusettsAges 18 years+ - NCT07614386Recruiting
Radial artery access outcomes in heart and vessel procedures
This registry collects data from patients undergoing heart or blood vessel procedures using a small artery in the wrist (radial or ulnar artery) for access. Researchers track outcomes to better understand the safety and effectiveness of this approach.
Mersin, MezitliAges 18 years+ - NCT07655206Recruiting
Home exercise for moderate to severe PAD
This study tests whether doing simple leg exercises at home with a small, portable pedal machine can help improve walking and blood flow in people with moderate-to-severe PAD. It's for people who cannot or prefer not to join a hospital-based exercise program.
Lévis, QuebecAges 18 years+ - NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07023965Enrolling by invitation
Long-term follow-up study for gene therapy in critical limb ischemia
This study follows up with people who previously took part in a clinical trial testing an experimental gene therapy for critical limb ischemia (severe leg pain or sores due to blocked arteries). It aims to see how well the treatment works over time. If you were in that earlier trial and received at least one dose, joining this follow-up could help researchers learn more about the therapy's lasting effects.
Beijing, Beijing MunicipalityAges 20–85 - NCT06933992Enrolling by invitation
Chocolate balloon for blocked leg arteries
This trial tests a special balloon called the Chocolate Balloon Catheter to open blocked leg arteries. It may help people with peripheral artery disease avoid more invasive surgery.
HangzhouAges 18–80 - NCT06542432Enrolling by invitation
Genetic risk test for heart disease prevention
This trial uses a polygenic risk score to see if knowing your genetic risk for coronary artery disease can help prevent a first heart attack. If you have an intermediate 10-year risk and no prior heart events, you may be eligible.
Rochester, MinnesotaAges 40–70
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Common questions
- Are there clinical trials for peripheral arterial disease?
- Yes. Clin2 currently lists 223 recruiting peripheral arterial disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral arterial disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral arterial disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.