Clinical trials
Peripheral Vascular Diseases clinical trials
Below are recruiting peripheral vascular diseases clinical trials, each written for real people, not researchers. We’re tracking 111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04916327Recruiting
Exercise program study for mental health and blood vessel health
This study tests whether an exercise training program can improve how well your blood vessels work in people with certain mental health conditions. You may join as someone with PTSD, someone with generalized anxiety, or as a healthy control group.
Richmond, VirginiaAges 18–35 - NCT04016649Recruiting
Study measures how leg veins move and respond
This study measures the properties of human saphenous and popliteal veins. If you’re having certain lower-leg procedures, your care team may collect information to better understand vein function and support future treatment.
Limerick, LimerickAges 18 years+ - NCT06693245Recruiting
Pain during microwave treatment for varicose veins
This study looks at how much pain people feel during a microwave treatment for varicose veins in the leg. It aims to understand what factors affect pain, so the treatment can be more comfortable for future patients.
Chengdu, SichuanAges 18–90 - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT07558174Recruiting
Monitoring blood flow during leg artery surgery with imaging
This study tests a special imaging camera that measures blood flow in your leg before, during, and after surgery to improve the artery. The goal is to help doctors see in real time whether the surgery is working properly.
Leiden, South HollandAges 18 years+ - NCT07161583Recruiting
Advanta VXT and Flixene Graft Registry
This registry follows people who have already received an Advanta VXT or Flixene graft to repair or replace a peripheral artery. It collects information from medical records to see how the grafts perform over time.
Boston, MassachusettsAges 18 years+ - NCT06206369Recruiting
AI tools to predict blood vessel disease risk and progression
This trial uses artificial intelligence to develop better ways to predict the risk and progression of two blood vessel conditions: abdominal aortic aneurysm (a bulging in the main belly artery) and peripheral artery disease (narrowed arteries in the legs). If you have one of these conditions, researchers want to learn from your data to improve future care.
HelsinkiAges 40–90 - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Little Rock, ArkansasAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT06544135Recruiting
Thermal camera study for blood flow in PAD with tissue loss
This study uses a special camera that detects heat to see blood flow in your leg before and after a procedure to open blocked arteries.
Beachwood, OhioAges 18–99 - NCT07052435Recruiting
Measuring pressure and flow during leg artery treatment
This study looks at how well blood flows through leg arteries after using a balloon to open blockages. It uses special measurements to check if the treatment fully restores blood flow, which may help guide future treatments.
PátraiAges Any age - NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT04912323Recruiting
Drug dissolving stent for blocked below-knee arteries
This trial studies a drug-eluting dissolving scaffold placed in blocked arteries below the knee to improve blood flow. It may help people whose leg circulation problems are severe enough to limit walking or threaten the limb, but only if their blockages fit specific imaging and procedure requirements.
GrazAges 18–90 - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT05236374Recruiting
Daily beef in a heart-healthy diet to study zinc cells
This study tests whether eating daily beef as part of a heart-healthy diet changes how your body’s cells handle zinc, a mineral important for many functions. It’s designed for older adults and includes strict diet and medication rules to keep results accurate.
Davis, CaliforniaAges 55–70 - NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT06687590Recruiting
Serranator POINT FORCE registry for leg and dialysis access
This registry study is following patients whose blocked leg or dialysis access arteries are treated with a special balloon (Serranator) that helps open the vessel. The goal is to see how well the device works in real-world use.
Scottsdale, ArizonaAges 18 years+ - NCT06605209Recruiting
A covered stent study for iliac artery blockage
This trial tests a balloon-expandable covered stent to treat blockages in the iliac artery (a major blood vessel in your pelvis). It may be an option for people with leg pain from poor blood flow.
Beijing, Beijing MunicipalityAges 18–80 - NCT05145517Recruiting
Follow-up study for people who received a JOTEC vascular graft
This study tracks people 18 and older who were treated with a JOTEC vascular graft. It checks how well the graft and follow-up care work over time for certain blood vessel problems.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT05545865Recruiting
Test how grape-based drinks affect blood flow response
This study tests whether a grape product (“Chardonnay Marc”) can change how your blood vessels respond to stress, measured with a finger sensor. It may help researchers understand how diet influences circulation in people with a low baseline blood-flow response.
Davis, CaliforniaAges 30–50 - NCT07076082RecruitingPhase 4
Vascular trial registry for leg artery procedures
This study is a registry that collects information on people who have or will have a leg artery procedure to open blocked blood vessels. It helps doctors learn more about how well these procedures work and how to improve care.
Detroit, MichiganAges 45 years+ - NCT06275113Recruiting
Prevention program for heart and artery disease
This study tests a prevention program for people who have already had a heart event, stroke, or leg artery blockage. It is designed to help reduce the risk of future heart problems.
Canicattì, AGAges 18 years+
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Common questions
- Are there clinical trials for peripheral vascular diseases?
- Yes. Clin2 currently lists 111 recruiting peripheral vascular diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral vascular diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral vascular diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.