Clinical trials
Pharmacodynamics clinical trials
Below are recruiting pharmacodynamics clinical trials, each written for real people, not researchers. We’re tracking 160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06987539RecruitingPhase 2
Inebilizumab for children with generalized myasthenia gravis
This study tests a new drug called inebilizumab for children with generalized myasthenia gravis (gMG), a condition causing muscle weakness. The drug aims to reduce the immune system's attack on nerves, which may improve symptoms. The study will check how safe and effective it is for young patients.
Philadelphia, PennsylvaniaAges 2–17 - NCT06980428RecruitingPhase 1
Safety study of AZD4954 in people with or without high Lp(a)
This trial tests a new drug called AZD4954 for safety. It includes healthy volunteers and people with high Lp(a) or dyslipidemia. The goal is to see if the drug is safe and how the body processes it.
Glendale, CaliforniaAges 18–70 - NCT05205109RecruitingPhase 1
Testing a new melanoma drug alone and with pembrolizumab
This early-stage trial tests ATG 037 to see if it’s safe and how it works in the body, as well as whether it may help people with advanced melanoma. It compares treatment given alone and treatment given together with pembrolizumab, especially in melanoma that has progressed after prior immunotherapy.
Sydney, New South WalesAges 18 years+ - NCT06120582RecruitingPhase 1/Phase 2
Gene therapy safety study for severe hemophilia B
This study tests a new gene therapy called ANB-002 for men with severe hemophilia B (factor IX levels at or below 2%). The goal is to see if it's safe and how well it might help your blood clot normally.
HomyelAges 18 years+ - NCT06934408RecruitingPhase 1
Safety study of HRS-5817 injection in healthy adults
This early-phase trial tests the safety and tolerability of a new injection called HRS-5817 in healthy volunteers. It helps researchers understand how the drug moves through the body and what side effects it might have.
Hefei, AnhuiAges 18–55 - NCT06916806RecruitingPhase 1
Study of AZD5492 for lupus, myositis, or rheumatoid arthritis
This trial tests an investigational drug called AZD5492 for people with active lupus, inflammatory myositis, or rheumatoid arthritis who haven't responded well to other treatments. It aims to see if the drug is safe and how it works in the body.
Anniston, AlabamaAges 18–70 - NCT06829563RecruitingPhase 1
Testing safety of new diabetes drug RZ-629
This early-phase study tests a new medicine called RZ-629. It looks at how safe it is, how the body processes it, and how it works in both healthy people and people with type 2 diabetes. If you have diabetes, you can join if your blood sugar is well controlled on your current pills.
AdelaideAges 18–65 - NCT06755450RecruitingPhase 1
Study of AUR112 for advanced lymphoma or CLL
This trial tests a new oral medication called AUR112 for people with advanced lymphoma or CLL that has not responded to at least 2 prior treatments. The goal is to see if it is safe and how it works in the body.
Vadodara, GujaratAges 18–99 - NCT06736587RecruitingPhase 1
Safety study of DWP212525 in healthy adults
This trial studies a new drug (DWP212525) in healthy volunteers to see how safe it is and how the body processes it. If you are a generally healthy adult, you could help researchers learn about the drug's effects.
SeoulAges 19–55 - NCT06700096RecruitingPhase 3
Testing a new drug for adults with severe hemophilia B
This trial tests a single dose of ANB-002, an experimental therapy for hemophilia B. It aims to see if the drug is safe and effective for people with severe hemophilia B who have been treated with factor IX before and do not have inhibitors.
ChelyabinskAges 18 years+ - NCT06700070RecruitingEarly Phase 1
Testing a microdose drug in solid tumors before surgery
This study tests a tiny amount of an experimental drug (PBA-0111) injected directly into tumors that will be surgically removed later. The goal is to see how the drug affects the tumor tissue, which may help guide future treatments for solid tumors like head and neck cancer, certain sarcomas, or triple-negative breast cancer.
Shreveport, LouisianaAges 18 years+ - NCT06692933RecruitingEarly Phase 1
How hemp affects a common blood thinner
This study tests if a hemp product changes how the body processes the blood thinner clopidogrel (Plavix). You must be healthy, have used cannabis before without problems, and have a specific gene type that affects how these substances break down.
Spokane, WashingtonAges 21–64 - NCT06609005RecruitingPhase 1/Phase 2
Study of INV-9956 for advanced prostate cancer
This trial tests a new drug called INV-9956 in men with advanced prostate cancer that no longer responds to hormone therapy and has spread to other parts of the body. It aims to see if the drug is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT03850574RecruitingPhase 1/Phase 2
Tuspetinib for relapsed or hard-to-treat AML
This early-phase study tests tuspetinib in people with AML that has come back or did not respond to treatment. The goal is to learn whether it is safe and tolerable, how the drug behaves in the body, and whether it shows signs of benefit.
Birmingham, AlabamaAges 18 years+ - NCT06532474Recruiting
Muscle function study in SMA patients on SMN therapies
This study looks at how muscles work in children and young adults with spinal muscular atrophy (SMA) who are taking or starting SMN-directed therapies (like Evrysdi, Spinraza, or Zolgensma). It aims to understand the body's response to these treatments, which could help improve future care.
Memphis, TennesseeAges 5–20 - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT06441812RecruitingPhase 2
Long-term safety of a new asthma medicine
This trial tests a new medicine called SHR-1703 for people with eosinophilic asthma (a type of asthma with high levels of certain white blood cells). It looks at how safe the medicine is over time and if it helps control asthma attacks. You must already be using medium or high dose inhaled steroids plus another asthma medicine, and have had at least one asthma attack in the past year.
Chengdu, SichuanAges 18 years+ - NCT06430385RecruitingPhase 1/Phase 2
Study of ION440 for MECP2 Duplication Syndrome
This trial tests an experimental medicine called ION440 for people with MECP2 Duplication Syndrome. The medicine is given as an injection into the spinal fluid, and the study aims to check its safety and how well it works.
San Diego, CaliforniaAges 2–65 - NCT06349473RecruitingPhase 1
Study of SR604 in healthy people and those with bleeding disorders
This study tests a new drug called SR604 to see if it is safe and how it works in the body. It is for healthy men and for people with hemophilia A, hemophilia B, or factor VII deficiency who have frequent bleeding or are on preventive treatment.
Glendale, CaliforniaAges 18–60 - NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65 - NCT06150716RecruitingPhase 1
Study of a new drug for Pelizaeus Merzbacher disease in boys
This trial is testing an experimental drug (ION356) given by a lumbar puncture to see if it is safe and how it works in boys with Pelizaeus Merzbacher disease (PMD). The drug is designed to target the genetic cause of PMD.
Atlanta, GeorgiaAges 2–17 - NCT06089980Recruiting
Kratom product study for regular users
This study watches how regular kratom users react to their own kratom product. It aims to learn more about kratom's effects in real-world settings.
Baltimore, MarylandAges 21 years+ - NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT05987449RecruitingPhase 1/Phase 2
Study of NXT007 for people with hemophilia A
This study tests a new medicine called NXT007 for people with moderate or severe hemophilia A. The goal is to see if it is safe, well-tolerated, and can help prevent or reduce bleeding episodes, possibly reducing the need for standard treatments. You may be able to join if you have hemophilia A with or without inhibitors and meet other health requirements.
Sacramento, CaliforniaAges 2–59
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Common questions
- Are there clinical trials for pharmacodynamics?
- Yes. Clin2 currently lists 160 recruiting pharmacodynamics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pharmacodynamics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pharmacodynamics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.