Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,943 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00409435RecruitingPhase 2
Pyridostigmine trial for postural tachycardia syndrome symptoms
This trial tests whether pyridostigmine helps people with postural tachycardia syndrome (POTS), which causes heart rate to rise when you stand up and can lead to unpleasant symptoms. You would be screened based on your tilt-table heart-rate response and your standing-related symptoms.
Rochester, MinnesotaAges 15–55 - NCT02064673RecruitingPhase 3
Adjuvant curcumin after prostate surgery to prevent cancer return
This Phase 3 trial studies whether taking curcumin (a supplement made from turmeric) after radical prostatectomy can help keep prostate cancer from coming back. Participants are men with low-risk, surgery-only disease and undetectable PSA, and the study checks recurrence-free survival over time.
Dallas, TexasAges 30–80 - NCT00929006RecruitingEarly Phase 1
Testing progesterone effects on hormone timing during sleep in teens
This early-phase study tests whether a progesterone medicine can change when “luteinizing hormone” (a puberty-related hormone) pulses during wake versus sleep. It focuses on pubertal girls with either normal or higher-than-expected testosterone levels to see how their hormone timing responds.
Charlottesville, VirginiaAges 10–17 - NCT02897700RecruitingPhase 1
Testing chemotherapy choices for early breast cancer after surgery
This Phase 1 study tests different chemotherapy approaches in people with breast cancer that has been surgically removed but is early stage. It aims to find a chemotherapy plan that’s safe and works well right after surgery.
Ganzhou, JiangxiAges 18 years+ - NCT02502162Recruiting
Low-dose naltrexone for complex regional pain syndrome
This trial tests whether low-dose naltrexone can reduce symptoms of complex regional pain syndrome (CRPS), a long-lasting pain condition in an arm or leg. It may help by targeting pain signaling, but you must meet specific CRPS diagnosis and medication rules to join.
Palo Alto, CaliforniaAges 18–70 - NCT02455479RecruitingPhase 1
Safety study of a vaccine for cocaine dependence
This early-stage study tests how safe an experimental “cocaine vaccine” is and how the body reacts to it. You must also be in behavioral therapy, and the study aims to see whether the vaccine can be given safely to people with cocaine use disorder.
New York, New YorkAges 21–69 - NCT02889666RecruitingPhase 1
Chemo plus surgery for recurrent lung cancer
This Phase 1 trial tests whether giving chemotherapy along with surgery is safe and tolerable for people with recurrent non-small cell lung cancer. It may help guide future treatment for cancer that has returned, especially if it has not spread to distant sites.
Changchun, JilinAges 18–75 - NCT02781519RecruitingPhase 1
Study how THC affects men and women who have used cannabis before
This Phase 1 study tests how delta-9 THC (the main active ingredient in cannabis) affects healthy adults, and whether the effects differ by gender. It may help researchers understand risks and responses to THC, which could guide safer use and future treatments.
West Haven, ConnecticutAges 18–55 - NCT02423395RecruitingPhase 3
Orphenadrine for muscle cramps in people with cirrhosis
This trial tests whether orphenadrine (a medication used to reduce muscle cramping) can lessen muscle cramps in people who have cirrhosis of the liver. It may help if your cramps happen often, but you must avoid certain medication conflicts and health situations.
TantaAges Any age - NCT02484248RecruitingPhase 3
Ketotifen for kids with stomach pain and duodenal eosinophilia
This study tests whether ketotifen can improve long-lasting stomach pain in children whose biopsies show high levels of a certain immune cell type in the small intestine. It may help if standard stomach-acid medicines and montelukast did not work well enough.
Kansas City, MissouriAges 8–17 - NCT02811510RecruitingPhase 1
Study of THC effects on people with past cannabis use
This Phase 1 study tests how THC (the main active ingredient in cannabis) affects healthy adults, and whether effects differ by gender. It’s designed to learn about short-term body and brain responses to THC.
West Haven, ConnecticutAges 18–55 - NCT02608996RecruitingPhase 1/Phase 2
Nesiritide test for hard-to-control blood pressure
This Phase 1/2 study tests nesiritide, a medicine that affects blood vessels and heart strain, to see if it can improve blood pressure control in people with hypertension. It’s mainly for people whose blood pressure stays high even during the day despite medication.
OsloAges 18–79 - NCT02314988RecruitingPhase 2/Phase 3
Tranexamic acid to reduce bleeding in spine surgery
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
San Francisco, CaliforniaAges 18–80 - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT02902198Recruiting
Study of taste changes before and after bariatric surgery
This study looks at how your sense of taste works before and after bariatric weight-loss surgery. It may help doctors understand why eating patterns change after surgery.
BaselAges 18–55 - NCT02446262Recruiting
Study of how the brain and mind shape pain in healthy adults
This study tests how people sense heat and pain, and how the brain and emotions may influence that experience. It is designed for healthy adults and may involve training sessions and (for some parts) MRI scanning.
Bethesda, MarylandAges 18–50 - NCT02521311RecruitingPhase 2
Clemastine to help restore nerve covering in optic neuritis
This Phase 2 trial tests whether clemastine can help regrow the protective covering around the optic nerve after acute optic neuritis (an inflammation-related vision problem). It may help improve vision recovery and signal how well “remyelination” happens.
San Francisco, CaliforniaAges 18–55 - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT03202303RecruitingPhase 2
CBDV treatment study for children with autism irritability
This Phase 2 study tests CBDV, a form of cannabis-based medicine, compared with placebo (dummy medicine) in children with autism who have significant irritability and social challenges. It aims to see whether CBDV can improve behavior and overall symptom severity safely over the study period.
New York, New YorkAges 5–18 - NCT03368092RecruitingPhase 3
Inhaled medication to prevent lung failure after severe trauma
This trial tests whether inhaled dornase alfa can reduce the risk of respiratory (lung) failure in adults with severe trauma who are on a breathing machine in the ICU. If it works, it may help patients spend less time with dangerous breathing complications.
StrasbourgAges 18 years+ - NCT07675200Recruiting
Miricell study on healthy aging and cell cleanup
This study tests whether a supplement called Miricell can improve markers of healthy aging and help your cells clean out damaged parts. If you are healthy, between 40 and 70 years old, and willing to follow a specific diet and visit schedule, you may be able to join.
Canfield, OhioAges 40–70 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT05498116RecruitingPhase 4
Montelukast to improve kidney and blood vessel function in type 1 diabetes
This trial tests whether montelukast, a medicine commonly used for allergies, can improve kidney health and blood vessel function in adults with long-term type 1 diabetes. You may join a treatment group and have kidney and circulation measurements taken over the study period.
Aurora, ColoradoAges 18–80 - NCT07204639RecruitingPhase 2
Testing CBP-0276 for moderate to severe psoriasis
This trial tests a new medication, CBP-0276, to see if it improves psoriasis symptoms and quality of life. It is for people with moderate to severe plaque psoriasis who might need stronger treatment.
Mexico CityAges 18–70
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,943 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.