Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05842174RecruitingPhase 1/Phase 2
Checking a new treatment approach for liver cancer needing TACE
This early-stage trial studies a new strategy for hepatocellular carcinoma (a type of liver cancer) in people who are planned to receive TACE, a procedure that delivers treatment through the liver’s blood supply. It aims to test whether targeting a specific cell survival process can improve how well the treatment works and is tolerated.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05835310RecruitingPhase 3
IV anifrolumab for active lupus in children
This study tests whether an intravenous medicine called anifrolumab can safely improve active systemic lupus (SLE) in children. If you qualify, you may receive the study treatment and be closely monitored for safety and lupus symptoms.
Phoenix, ArizonaAges 5–17 - NCT04566991RecruitingPhase 2
Deferoxamine after aneurysm brain bleed to improve recovery
This trial studies deferoxamine, a medicine that targets iron-related injury, in people with an aneurysmal subarachnoid hemorrhage (a brain bleed caused by a burst aneurysm). It aims to improve neurologic recovery after the aneurysm is treated.
Ann Arbor, MichiganAges 18–80 - NCT05834777RecruitingPhase 3
Prevent low blood pressure during dialysis by blocking bradykinin
This Phase 3 trial tests a medicine that blocks a body signal (bradykinin) to help prevent dangerous drops in blood pressure during hemodialysis. If you often get “intradialytic hypotension,” this study may help you dialyze more safely.
Nashville, TennesseeAges 18–80 - NCT05841758RecruitingPhase 4
Hydroxychloroquine to reduce steroid use in sarcoidosis
This trial studies whether hydroxychloroquine can control extrapulmonary sarcoidosis (sarcoidosis outside the lungs) using less steroid treatment. It may help people who need systemic therapy for problems such as eyes, skin, bones, joints, nerves, ENT areas, or high calcium levels from sarcoidosis.
AvignonAges 18 years+ - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05842330RecruitingPhase 3
Testing ADHD treatment benefits for people in custody
This Phase 3 study tests whether treating attention-deficit/hyperactivity disorder (ADHD) helps people who are incarcerated. You might be eligible if you meet ADHD diagnosis requirements, can consent, and are able to take ADHD medicine safely.
Geneva, Canton of GenevaAges 18–65 - NCT05819138RecruitingPhase 3
Semaglutide for heart outcomes in adults with type 1 diabetes
This trial studies whether semaglutide can improve heart and blood-vessel outcomes in people with type 1 diabetes who use an insulin pump or automated insulin delivery. It may help reduce cardiovascular risks, but you must meet several health and medication-safety requirements.
Aurora, ColoradoAges 18–49 - NCT05838274Recruiting
Study of alcohol effects and brain scans in bipolar disorder
This study gives a controlled amount of alcohol and uses brain MRI scans to understand how alcohol affects people with bipolar disorder. It may help researchers find brain and behavior patterns that explain differences in alcohol responses.
Austin, TexasAges 21–26 - NCT05822609RecruitingPhase 2
Semaglutide for kidney disease in adults with type 1 diabetes
This Phase 2 study tests semaglutide (a diabetes and weight-related medicine) to see if it can slow or improve diabetic kidney disease in people with type 1 diabetes. You may be able to join if you have type 1 diabetes for at least 5 years and ongoing signs of kidney damage measured in urine tests.
Aurora, ColoradoAges 18 years+ - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT05838716RecruitingPhase 3
Vitamin D During Hormone Therapy for Prostate Cancer
This trial studies whether taking vitamin D while you are on prostate hormone therapy (ADT) affects your health outcomes. It may help by keeping vitamin D levels in a safe range during treatment.
Newark, DelawareAges 50 years+ - NCT05823727Recruiting
Collagen supplement study before and after knee replacement
This study tests whether taking collagen peptides can improve how knee tissues heal and remodel after total knee arthroplasty (knee replacement). It also looks at functional recovery and wound healing, especially during the physical therapy period in Little Rock.
Little Rock, ArkansasAges 50–75 - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05822141Recruiting
Omega-3 effects on body fat in cold exposure
This study tests whether omega-3 (fish oil–type) changes how your body fat responds when you are exposed to cold. It may help researchers understand how to regulate “brown fat,” which can be involved in how your body uses energy during cold.
Bloomington, IndianaAges 18–40 - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05835037RecruitingPhase 4
Zinc supplement study for prediabetes blood sugar control
This study tests whether taking zinc can improve how your body controls blood sugar in people with prediabetes. It may help slow the progression toward type 2 diabetes, but you would need to meet specific health and medication criteria.
Lancaster, PennsylvaniaAges 18–80 - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT05835505RecruitingPhase 2
Detox medicine study for primary sclerosing cholangitis
This Phase 2 trial studies a “detoxification” approach to improve liver and bile-duct function in people with primary sclerosing cholangitis (PSC). It may help lower abnormal bile flow markers and see whether the treatment is safe for your liver.
Chestnut Hill, MassachusettsAges 18–75 - NCT05843786RecruitingPhase 3
Interferon gamma for ventilator pneumonia in ICU
This trial tests whether a medicine called interferon gamma can improve outcomes in adults with a first episode of pneumonia that develops after being on a ventilator in the ICU. It is designed for specific ICU timing, infection severity, and immune marker levels, and it compares treatment on top of standard care.
LimogesAges 18 years+ - NCT05815797RecruitingPhase 2
Chinese herbal formula for mild to moderate psoriasis
This trial tests an herbal formula called Shuiniujiao Dihuang Decoction for people with mild to moderate plaque psoriasis. It may help reduce psoriasis symptoms without using stronger medicines.
Hong KongAges 18–75 - NCT05837104RecruitingPhase 2
Magnesium and vitamin B6 for early bipolar depression
This Phase 2 trial tests whether magnesium plus vitamin B6 can reduce depressive symptoms in people who are newly diagnosed with bipolar I disorder. It also checks for safety over a short, 4-week treatment period.
Belmont, MassachusettsAges 18–50 - NCT05829655RecruitingEarly Phase 1
Measuring drug cravings in people with opioid use disorder
This study tests whether the medication suvorexant can reduce drug cravings in people with opioid use disorder. You will take either suvorexant or a placebo and have your cravings measured in a safe setting.
Baltimore, MarylandAges 18–65 - NCT05832567Recruiting
Study of hidden and open placebo effects in stroke recovery
This study looks at how “open” (told) and “hidden” (not told) placebo effects may change arm recovery after a long-term stroke. You would do recovery-related assessments and likely receive brain-stimulation or related procedures to test these effects.
Cambridge, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.