Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06658821Enrolling by invitation
Study of LDL557 for knee arthritis in older adults
This trial tests whether a supplement called LDL557 can improve early-stage knee arthritis in people over 65. It aims to reduce pain and slow joint damage.
TaichungAges 45–80 - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Garden Grove, CaliforniaAges 18–70 - NCT06651567RecruitingPhase 2
Study of a new drug for agitation in Alzheimer's disease
This study tests an experimental medication, ITI-1284, to see if it can safely reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, aggression, or irritability, and this drug aims to help manage those symptoms.
Anaheim, CaliforniaAges 55 years+ - NCT06654193RecruitingPhase 1/Phase 2
Stem cells vs placebo for acute kidney injury
This trial tests whether donor stem cells (HB-adMSCs) can help patients with acute kidney injury from trauma, burns, or crush injuries. It aims to see if the treatment improves kidney function compared to a placebo.
Birmingham, AlabamaAges 18–75 - NCT06655324RecruitingPhase 1
Safety study of two EBV vaccines in healthy people
This study tests two experimental vaccines (V350A and V350B) designed to prevent Epstein-Barr virus infection. It is looking for healthy adolescents and adults to see if the vaccines are safe and produce a good immune response.
Glendale, CaliforniaAges 12–30 - NCT06656325Recruiting
Laser treatment for gum disease study
This study tests a special low-level laser (Erchonia FX-405) as an extra treatment for gum disease (periodontitis). It aims to see if adding this laser to standard care helps improve gum health and reduce infection.
Thousand Oaks, CaliforniaAges 22–75 - NCT06651294Recruiting
Study of kidney stone supplement after laser treatment
This trial tests a supplement called Neorenal Forte to help clear tiny leftover kidney stone pieces after laser surgery. If you have small fragments left after your procedure, this study may help you get rid of them.
BurgasAges 18–65 - NCT06656416RecruitingPhase 2
Study of ALTO-100 for bipolar depression
This study tests an investigational drug called ALTO-100 for people with bipolar disorder who are currently experiencing depression. It aims to see if ALTO-100 can help improve depressive symptoms when added to your current mood stabilizer or antipsychotic medication.
Birmingham, AlabamaAges 18–70 - NCT06651281RecruitingPhase 3
Long-term safety and effectiveness of tulisokibart for Crohn's or colitis
This study gives tulisokibart to people who already took part in an earlier trial for Crohn's disease or ulcerative colitis and are still benefiting from it. The goal is to see how safe and effective the medicine is over a longer period.
Bristol, ConnecticutAges Any age - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Scottsdale, ArizonaAges 18–100 - NCT06652438RecruitingPhase 3
Revumenib plus standard drugs for NPM1 or KMT2A AML
This trial tests adding a new targeted drug, revumenib, to two standard AML medicines (azacitidine and venetoclax) for adults with a specific gene change (NPM1 mutation or KMT2A rearrangement) who cannot receive strong chemotherapy. The goal is to see if the combination works better.
Los Angeles, CaliforniaAges 18 years+ - NCT06651177RecruitingPhase 2
Tirzepatide with buprenorphine for opioid use disorder
This study tests whether adding tirzepatide, a medication used for weight and blood sugar, to buprenorphine treatment helps people with opioid use disorder. It aims to see if the combination improves outcomes compared to buprenorphine alone.
Jacksonville, FloridaAges 18 years+ - NCT06653569RecruitingPhase 3
Baloxavir for flu in hospitalized adults
This trial tests if the antiviral drug baloxavir can help adults hospitalized with influenza recover faster. It compares baloxavir to a placebo to see if it improves symptoms and outcomes.
Geneva, Canton of GenevaAges 18 years+ - NCT06653738RecruitingPhase 3
Testing empagliflozin and diet advice for kidney stone prevention
This trial tests if a medication called empagliflozin, combined with personalized diet advice, can help prevent kidney stones from coming back. It may be an option if you've had two or more kidney stone events in the last 10 years and your stones were mostly calcium-based.
AmiensAges 18 years+ - NCT06647524RecruitingPhase 2
How cannabis affects the aging brain
This study uses brain scans (fMRI) to see how THC (the active ingredient in cannabis) affects the brain as people age. If you are a cannabis user without current dependence or health issues, you may help researchers understand these effects.
Hartford, ConnecticutAges 18–75 - NCT06648759Recruiting
Vagal stimulator to reduce need for nasogastric tube
This trial tests if a device that stimulates the vagus nerve can help patients avoid needing a nasogastric tube after major abdominal surgery, specifically if they develop a slowdown in bowel function called postoperative ileus.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06655454RecruitingPhase 2
Numbing medicine after root canal for pain relief
This study tests whether a long-acting numbing medication (bupivacaine) given after a root canal can reduce pain better than a standard short-acting numbing medicine. It is for people who need a root canal for a tooth that is causing sharp, constant pain.
New York, New YorkAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06637254Enrolling by invitationPhase 2
Testing an oral tablet for hard-to-control asthma
This study tests an oral tablet (HSK31858) to see if it helps control asthma in people whose asthma is not well managed with current inhalers. It focuses on those with a specific type of asthma where certain blood cells are low.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06632600RecruitingPhase 2
Study of LXE408 for people with chronic Chagas disease
This trial tests a new drug called LXE408 for people with chronic Chagas disease. It aims to see if the drug is safe and effective, and participants will also receive standard treatment with benznidazole.
Sylmar, CaliforniaAges 18–60 - NCT06632444RecruitingPhase 3
Study of survodutide for liver disease NASH/MASH with fibrosis
This trial tests an investigational drug called survodutide for people with NASH or MASH, a type of fatty liver disease that also has liver scarring (moderate or advanced fibrosis). The goal is to see if the drug can improve the condition.
Birmingham, AlabamaAges 18 years+ - NCT06641466RecruitingPhase 3
Study of Rimegepant for preventing menstrual migraine in women
This study tests whether the medicine rimegepant can help prevent migraines that happen around your period. It is for women with regular menstrual cycles who have a history of menstrual migraines.
Phoenix, ArizonaAges 18–45 - NCT06638502RecruitingPhase 1/Phase 2
Testing HRX215 for liver recovery after surgery
This trial tests a drug called HRX215 to see if it is safe and helps the liver recover after surgery to remove colon cancer tumors that have spread to the liver. It is for people who are having either a minor or major liver resection and have a low risk of liver failure.
Baltimore, MarylandAges 18–75 - NCT06633016RecruitingPhase 2
ABX-002 for major depression (add-on treatment)
This trial tests a new medication called ABX-002 as an add-on to your current antidepressant. It's for people with moderate to severe depression who haven't gotten enough help from their current antidepressant alone.
Birmingham, AlabamaAges 18–65
Hear when a new Placebo trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,158 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.