Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04770012RecruitingPhase 3
Aspirin or clopidogrel after heart transplant
This study tests antiplatelet medicines (like aspirin or clopidogrel) in people who have had a heart transplant. The goal is to see if these medicines can safely help prevent blood-related complications after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT04769206RecruitingPhase 1/Phase 2
Boost nerve signaling to improve blood vessel function
This study tests a treatment aimed at increasing “rest-and-digest” nerve activity to improve how blood vessels work, especially in people with vascular oxidative stress. It is designed for African American adults and looks at whether the intervention can improve blood vessel-related health markers.
Nashville, TennesseeAges 18–60 - NCT04759001RecruitingPhase 1/Phase 2
Fecal treatment to clear gut bacteria resistant to antibiotics
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
RomeAges 18–90 - NCT04743791RecruitingPhase 4
Dupilumab study for clearing mucus in moderate to severe asthma
This study tests whether dupilumab improves how well mucus is cleared from the airways in adults with moderate to severe asthma. It may help find better ways to reduce mucus-related breathing problems in people with a specific asthma type.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04752774RecruitingPhase 1/Phase 2
Botox-like injection study for arm spasticity after stroke
This trial tests whether IPN10200, a Botox-like treatment, is safe and helps reduce stiff, tight upper-arm muscles caused by spasticity after stroke or brain injury. You may be able to join if you meet specific timing, prior-treatment, and muscle-stiffness measurements.
Downey, CaliforniaAges 18–70 - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT04678895RecruitingPhase 2
Low-dose naltrexone for nerve pain from diabetes
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Lebanon, New HampshireAges 18 years+ - NCT04628026RecruitingPhase 3
Venetoclax plus chemotherapy for new AML or high-risk MDS
This trial tests adding venetoclax to standard chemotherapy to help people with newly diagnosed acute myeloid leukemia (AML) or high-risk MDS (MDS-EB-2) live longer and reduce cancer activity. You may benefit if you’re eligible for intensive chemotherapy and meet specific blood, organ, and treatment timing requirements.
InnsbruckAges 18–75 - NCT04614714RecruitingPhase 2/Phase 3
Nicotinamide riboside to boost breast milk for very premature infants
This study tests whether an oral supplement called nicotinamide riboside can increase milk output in mothers of extremely premature babies. If it works, it may help you provide enough breast milk for your baby’s early NICU needs.
Sacramento, CaliforniaAges 18 years+ - NCT04653064Recruiting
Brain imaging study of how people feel heat and pain
This study uses MRI scans to understand how your brain responds to different feelings, including mild heat pain. It may help researchers learn more about pain and brain processing by comparing your responses during the tests.
Hanover, New HampshireAges 18 years+ - NCT04666636RecruitingPhase 2
Test a drug idea to activate fat that burns energy
This Phase 2 study tests whether a medication approach can activate “beige” fat, which may help the body burn more energy. It mainly looks for people with higher body weight and prediabetes who are not on diabetes medicines.
Lexington, KentuckyAges 35–65 - NCT04678167Recruiting
Special “ring” glasses for vestibular neuritis symptoms
This trial tests whether wearing “ring” glasses helps reduce symptoms from vestibular neuritis, a condition that causes spinning vertigo and balance problems. Participants may get the glasses being tested or look-alike placebo glasses (or not wear glasses), so the study can tell if the glasses truly help.
BrestAges 18 years+ - NCT04597437RecruitingPhase 2
Zanamivir for dengue that causes warning signs
This Phase 2 study tests whether zanamivir given through a vein can improve outcomes in people with dengue infection who have warning signs. It may help by reducing the body problems dengue can cause in blood vessels and fluid balance.
Barranquilla, AtlánticoAges 7 years+ - NCT04629547RecruitingPhase 2
Sleep study to help prevent Alzheimer’s disease
This trial tests whether treating sleep issues and measuring sleep can help lower the risk of Alzheimer’s disease before it starts. It focuses on older adults with no dementia signs yet.
St Louis, MissouriAges 65 years+ - NCT04616781RecruitingPhase 2/Phase 3
Ketone drink study for alcohol use disorder brain function
This study tests whether a ketone-based treatment (a ketone ester) can change brain activity in people with alcohol use disorder who are not currently seeking treatment. You may also have brain scans, so the study is looking for safe MRI eligibility and certain health factors.
Philadelphia, PennsylvaniaAges 21–65 - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT04597372RecruitingPhase 2
Tamsulosin for bladder urine retention after pelvic surgery
This trial studies whether tamsulosin can help drain the bladder when urine builds up after pelvic reconstructive surgery. It may help reduce the time and problems caused by “post-operative urinary retention.”
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04659317RecruitingPhase 3
Opioid-free pain plan for joint and arm surgeries
This Phase 3 study tests an opioid-free approach to pain control for certain orthopedic (bone/joint) surgeries. The goal is to help people manage surgical pain without using opioid pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04528082RecruitingPhase 3
Apremilast for children with frequent mouth ulcers from Behçet’s disease
This study tests apremilast to help reduce active, recurring mouth (oral) ulcers in children with Behçet’s disease. It may help if your child has had repeated mouth ulcers despite at least one non-biologic treatment.
BronAges 2–17 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT04576078RecruitingPhase 2
Nefopam for less pain after knee replacement surgery
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
Lyon, LyonAges 18–75 - NCT04538755Enrolling by invitationPhase 1/Phase 2
Testing a new drug for moderate to severe sleep apnea
This trial tests a drug called DAW2020 to see if it can improve how your body controls breathing during sleep. You may qualify if you have moderate to severe sleep apnea and are otherwise healthy.
Boston, MassachusettsAges 21–70 - NCT04555785RecruitingPhase 4
Testing platelet treatment in ICU patients after surgery
This trial studies whether a platelet-related treatment can work better in people in the ICU who need a platelet transfusion after surgery. It may help reduce bleeding by improving how platelets work when certain blood clotting proteins are already high.
BaselAges 18 years+
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,162 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.