Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06742333RecruitingPhase 2
Can bimekizumab delay early plaque psoriasis?
This trial tests if the drug bimekizumab can slow down chronic inflammation in people with early plaque psoriasis. It's for adults 18-44 with mild psoriasis who haven't used topical treatments recently.
Nice, Alpes-MaritimesAges 18–45 - NCT06286501Recruiting
Preventive treatment for teens at risk of oral diseases
This trial tests a new preventive treatment for teenagers at risk of tooth decay and gum disease. It uses a special mouthpiece device (Lumoral) to clean teeth better and see if it can prevent oral health problems.
Tampere, PirkanmaaAges 14–16 - NCT06710080RecruitingPhase 3
Testing a medicine to reduce inflammation in pneumonia patients
This trial tests if a medicine called icosapent ethyl can reduce inflammation in blood vessels for adults hospitalized with pneumonia. It aims to see if this treatment can help prevent complications.
Ottawa, OntarioAges 18 years+ - NCT06576063Recruiting
Light therapy for better oral hygiene in older adults
This study tests a special light therapy (called antibacterial photodynamic therapy) used with a device called Lumoral to improve oral hygiene in older adults. It may help reduce bacteria and plaque in people who can brush their teeth and follow the study routine.
Loviisa, UusimaaAges 65 years+ - NCT06701513Recruiting
Real-world study of deucravacitinib for plaque psoriasis
This study looks at how well deucravacitinib works for adults with moderate to severe plaque psoriasis in everyday medical practice. It helps doctors understand the real-world benefits of this treatment.
AmiensAges 18 years+ - NCT05984537RecruitingPhase 4
Bivalirudin during angioplasty for high-risk heart plaques
This study tests whether a blood thinner called bivalirudin, given during a procedure to open blocked heart arteries (PCI), helps blood flow better in the tiny vessels of the heart afterward. It is for people with a recent unstable heart condition and a high-risk plaque seen on a CT scan.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06649305Recruiting
Study of vulnerable plaque in heart arteries of people with diabetes
This study uses a special camera (OCT and NIRS) inside heart arteries to look for dangerous plaque in people with diabetes. It may help doctors decide the best treatment to prevent heart attacks.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05367297Recruiting
Registry study of heart plaque in South Asian adults
This study tracks coronary plaque (fatty deposits in heart arteries) in South Asian adults and compares them with people of other backgrounds. You may be asked to have a special heart CT scan and basic measurements to help researchers understand differences in heart disease risk.
Dallas, TexasAges 18 years+ - NCT04046237Recruiting
Treating gum disease to study heart artery inflammation after a heart attack
This study tests whether treating severe gum disease in people who recently had a heart attack can reduce inflammation in the artery plaque. It may help researchers understand if gum treatment could benefit heart health after a heart attack.
ParisAges 30–70 - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT06424860RecruitingPhase 1
Fish Oil, Metformin and Heart Health in PCOS
This trial tests whether fish oil and metformin can improve heart health in people with PCOS who are overweight or have high blood sugar or fats. It combines two common approaches to see if they work better together.
Edmonton, AlbertaAges 25–45 - NCT06404242Recruiting
Plaque features predict repeat stroke after middle cerebral artery blockage
This study looks at people who recently had a stroke caused by hardening of the arteries in the middle cerebral artery, a major blood vessel in the brain. The researchers use special MRI scans to see if the plaque (the fatty buildup) can predict whether another stroke might happen.
Ho Chi Minh City, Ho Chi Minh CityAges 45–100 - NCT06410690Recruiting
AI tool to predict high-risk coronary plaques from heart scans
This trial uses an artificial intelligence (AI) tool to analyze heart CT scans (CCTA) and identify dangerous plaque buildup that could lead to a heart attack. It aims to see if AI can better predict high-risk plaques in people with known or suspected coronary artery disease (CAD).
Milan, MilanAges 18 years+ - NCT06382051Recruiting
Improving Psoriatic Arthritis Screening in Psoriasis
This study tests a new way to screen for psoriatic arthritis (a type of joint inflammation) in people with psoriasis. It looks at a tool called PEST and aims to improve early detection.
Calgary, AlbertaAges 18 years+ - NCT06352645Recruiting
Testing a compact water flosser for gum health
This trial tests a new water flosser (Bixdo Ultra Compact) to see if it safely improves gum health in people with moderate to severe gum disease. You would use the flosser at home and attend check-ups for about 4 weeks.
Boston, MassachusettsAges 18–70 - NCT06313645Recruiting
Blood vessel aging and heart attack risk study
This study looks at how blood vessel aging relates to the type of fatty buildup in your arteries that can cause heart attacks. If you've had a recent heart attack, chest pain (angina), or minor artery disease and do not have advanced heart failure, kidney failure, active cancer, or prior bypass surgery, you may be able to join.
Milan, LombardyAges 18–75 - NCT05783804Recruiting
Early cholesterol-lowering to help reverse artery plaque
This trial studies whether starting strong cholesterol-lowering treatment early can reduce or reverse plaque in the arteries. It may help protect the heart over time, especially for people with inherited high cholesterol.
Amsterdam, North HollandAges 18–50 - NCT06182293Recruiting
Mouth bacteria in early systemic sclerosis
This study looks at the bacteria in the mouth (periodontal microbiota) of people with early systemic sclerosis compared to those without the condition. It may help understand if there is a link between oral health and systemic sclerosis.
StrasbourgAges 18 years+ - NCT05852145RecruitingPhase 1/Phase 2
Testing sweet drinks effect on children’s mouth health
This early-stage study looks at how drinking soft drinks with and without sweeteners affects children’s mouths and teeth. It may help researchers understand which types of sweet drinks contribute to more tooth damage.
Mexico City, CuahutemocAges 12–18 - NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT05994976Recruiting
Collecting skin samples from people with skin conditions
This study collects skin samples (like small biopsies or swabs) from people with certain skin conditions and from healthy volunteers. The samples help researchers learn more about these conditions and may lead to better treatments.
Montreal, QuebecAges 18 years+ - NCT05897645Recruiting
MRI study of artery plaque after recent stroke
This trial uses special brain MRI to look closely at plaque in certain brain arteries after an ischemic stroke (when a blood vessel is blocked). It may help researchers better understand which plaques are most dangerous soon after stroke.
ShenyangAges 40 years+ - NCT05893654Enrolling by invitationPhase 1/Phase 2
Melphalan treatment to shrink eye melanoma before other therapy
This early-phase study tests whether melphalan can be used to reduce (shrink) a type of eye cancer called choroidal melanoma before additional treatment. It may help by controlling tumor size while doctors closely monitor the eye and outcomes.
Ribeirão Preto, São PauloAges 18 years+ - NCT04681417RecruitingPhase 2/Phase 3
Eye-sparing treatment options for children with retinoblastoma
This trial studies whether newer “save-the-eye” treatment plans can control retinoblastoma (eye cancer) while keeping vision as good as possible. It compares different conservative treatment strategies depending on how the tumor looks and where it is.
Saint-Denis, La RéunionAges 6 months–6 years
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.