Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06844942Recruiting
Improving heart artery imaging for chest pain diagnosis
This trial uses a special camera called OCT to take detailed pictures of the heart's arteries. It aims to see if these pictures help doctors better understand blockages and decide on treatment for stable chest pain.
Warsaw, Mazowieckie VoivodenshipAges 18 years+ - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Phoenix, ArizonaAges 18 years+ - NCT06863545Recruiting
PCSK9 Inhibitors for High-Risk Coronary Plaques on CT
This study tests whether adding a PCSK9 inhibitor (a newer cholesterol-lowering shot) to standard treatment can reduce heart risks in people who have certain high-risk plaque features seen on a CT scan of their heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT06882564RecruitingPhase 3
Resveratrol mouthwash for bad breath study
This trial tests whether a special mouthwash with resveratrol (a natural plant compound) can help reduce bad breath caused by gum-related bacteria. It might be a good option if you have bad breath from gingivitis (mild gum inflammation) and are a non-smoking dental student.
Baghdad, Bab Al-MoadhamAges 20–24 - NCT06887894Recruiting
Studying unstable plaque in the carotid artery
This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.
Roma, RMAges 18 years+ - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT06902740RecruitingPhase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing
This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06997055Recruiting
Study of Steqeyma® biosimilar in Crohn's and psoriasis
This study follows people with Crohn's disease or plaque psoriasis who are switching from the reference Ustekinumab to a biosimilar (Steqeyma®). It aims to see how well the biosimilar works in real-world settings.
AmiensAges 18 years+ - NCT07029360Recruiting
Coenzyme Q10 and Probiotics for Gum Health in Pregnancy
This trial tests whether adding coenzyme Q10 and probiotics to standard gum treatment can improve gum health and reduce inflammation in pregnant women. If you are in your second or third trimester and have gum concerns, this treatment may help both you and your baby.
Pavia, LombardyAges 18 years+ - NCT07104487RecruitingPhase 2
PET/MRI scan to detect inflammation in carotid artery disease
This study tests whether a special type of PET/MRI scan can help doctors see inflammation in the carotid artery after a stroke or mini-stroke. By using a radioactive tracer, the scan may identify which patients have dangerous plaque buildup that could lead to another stroke.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07119840Recruiting
Listerine vs. chlorhexidine mouthwash during braces
This trial compares two common mouthwashes (Listerine and chlorhexidine) to see which works better for keeping your teeth and gums healthy while you have braces. If you are getting braces, you can join to help find out which rinse helps prevent plaque and gum problems.
Swāt, KPKAges 13–40 - NCT07166731Recruiting
Carotid stent vs. medication for recent stroke risk
This trial tests if a carotid artery stent plus medication is better than medication alone at preventing another stroke in people who recently had a stroke or eye blockage caused by a non-narrowing but risky carotid plaque.
Solingen, North Rhine-WestphaliaAges 18 years+ - NCT07169201Recruiting
CT scan for heart in people with diabetes or heart disease
This study uses a special CT scan to look at your heart more closely. It may help people with known or suspected heart problems or type 2 diabetes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT07261306RecruitingEarly Phase 1
Methotrexate vs tofacitinib pills for plaque psoriasis
This study compares two oral pill treatments—methotrexate and tofacitinib—for people with chronic plaque psoriasis that is moderate to severe and hasn't responded well to creams. The goal is to see which pill works better at clearing skin.
Lahore, Punjab ProvinceAges 18–70 - NCT07265284RecruitingPhase 3
IBI112 for teens with moderate to severe plaque psoriasis
This study tests a new medicine called IBI112 for teens aged 12–18 with moderate to severe plaque psoriasis. It aims to see if the medicine is safe and can help clear skin better than placebo.
Beijing, Beijing MunicipalityAges 12–18 - NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT07291609Recruiting
Microplastics in heart artery patients
This study looks for tiny plastic particles in the blood of people with chronic heart artery disease. You will have a standard CT scan and an invasive angiogram anyway, and researchers will check your blood samples for microplastics.
CasertaAges 18 years+ - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07301034RecruitingPhase 3
Ziltivekimab for plaque after a heart attack
This study tests a drug called ziltivekimab to see if it can reduce fatty plaque buildup in heart arteries after a heart attack. It's for people who had a heart attack treated with a stent and have mild blockages in other arteries.
ViennaAges 18 years+ - NCT07349875RecruitingPhase 4
Colchicine for non-severe coronary plaque: a trial
This trial tests if the anti-inflammatory drug colchicine can help people with non-severe coronary artery plaque seen on a CT scan. It may be an option if you have stable chest pain or related symptoms and your heart arteries are partly blocked but not severely.
NanjingAges 18 years+ - NCT07355400Recruiting
NeoPill device for reducing mouth bacteria in braces patients
This trial tests a device called NeoPill to reduce bacteria in the mouths of people with braces. It involves a single visit and may help control oral bacteria levels.
LimassolAges 18 years+ - NCT07364565Recruiting
Green tea mouthwash for plaque and gum health
This trial tests whether a pure green tea mouthwash can reduce plaque and gum inflammation better than a placebo or an essential oils mouthwash. It may be a good option if you have healthy gums and are looking for a natural alternative.
Irbid, Irbid GovernorateAges 18 years+
Hear when a new Plaque trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 181 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.