Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06365502Recruiting
Preventing future heart attacks with drug-coated balloon
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Beijin, Beijing MunicipalityAges 18–80 - NCT06410690Recruiting
AI tool to predict high-risk coronary plaques from heart scans
This trial uses an artificial intelligence (AI) tool to analyze heart CT scans (CCTA) and identify dangerous plaque buildup that could lead to a heart attack. It aims to see if AI can better predict high-risk plaques in people with known or suspected coronary artery disease (CAD).
Milan, MilanAges 18 years+ - NCT06424860RecruitingPhase 1
Fish Oil, Metformin and Heart Health in PCOS
This trial tests whether fish oil and metformin can improve heart health in people with PCOS who are overweight or have high blood sugar or fats. It combines two common approaches to see if they work better together.
Edmonton, AlbertaAges 25–45 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT06477237RecruitingPhase 3
Testing a new psoriasis shot for moderate to severe plaque
This trial tests a new medication called HB0017 for moderate to severe plaque psoriasis. It aims to see if it is safe and effective in reducing skin symptoms and improving quality of life.
Jiangmen, GuangdongAges 18–75 - NCT07489885RecruitingPhase 2
Study of D-2570 for moderate to severe plaque psoriasis
This trial tests an experimental drug, D-2570, for people with moderate to severe plaque psoriasis. It aims to see if the medication can safely improve skin symptoms.
Birmingham, AlabamaAges 18–70 - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT06576063Recruiting
Light therapy for better oral hygiene in older adults
This study tests a special light therapy (called antibacterial photodynamic therapy) used with a device called Lumoral to improve oral hygiene in older adults. It may help reduce bacteria and plaque in people who can brush their teeth and follow the study routine.
Loviisa, UusimaaAges 65 years+ - NCT06649305Recruiting
Study of vulnerable plaque in heart arteries of people with diabetes
This study uses a special camera (OCT and NIRS) inside heart arteries to look for dangerous plaque in people with diabetes. It may help doctors decide the best treatment to prevent heart attacks.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06671106Recruiting
Mouthrinse for Teens with Early Gum Disease
This trial tests a special mouthrinse containing amine and zinc lactate to treat plaque-induced gingivitis (gum inflammation caused by plaque) in teenagers. If you or your teen have early gum disease and are eligible for free dental care through the Regional Health Service, this study may offer a home-based treatment option.
FerraraAges 12–14 - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT06701513Recruiting
Real-world study of deucravacitinib for plaque psoriasis
This study looks at how well deucravacitinib works for adults with moderate to severe plaque psoriasis in everyday medical practice. It helps doctors understand the real-world benefits of this treatment.
AmiensAges 18 years+ - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Phoenix, ArizonaAges 55 years+ - NCT07582783Recruiting
Treatment Persistence with Guselkumab for Moderate-to-Severe Plaque Psoriasis
This study tracks how well patients stick with guselkumab, a biologic injection medication for moderate-to-severe plaque psoriasis. Researchers want to understand real-world treatment outcomes in Romania to help improve psoriasis care.
BârladAges 18 years+ - NCT06710080RecruitingPhase 3
Testing a medicine to reduce inflammation in pneumonia patients
This trial tests if a medicine called icosapent ethyl can reduce inflammation in blood vessels for adults hospitalized with pneumonia. It aims to see if this treatment can help prevent complications.
Ottawa, OntarioAges 18 years+ - NCT06742333RecruitingPhase 2
Can bimekizumab delay early plaque psoriasis?
This trial tests if the drug bimekizumab can slow down chronic inflammation in people with early plaque psoriasis. It's for adults 18-44 with mild psoriasis who haven't used topical treatments recently.
Nice, Alpes-MaritimesAges 18–45 - NCT06749106Recruiting
Using MRI to find bleeding in neck artery plaque
This study uses MRI scans that are already done as part of your stroke care to look for bleeding inside plaque in the neck arteries. The goal is to see if this bleeding can help predict stroke risk.
MunichAges 18 years+ - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT06754956Recruiting
MRI Study of Artery Plaques Using Different MRI Scanners
This study investigates the build-up of fatty deposits called plaques in arteries of the brain and neck using two different strengths of MRI scanners. It aims to understand how well these MRI techniques can image the plaques, which could help doctors better diagnose and manage stroke risk.
ShanghaiAges 18–95 - NCT06757569Recruiting
New PET scan for detecting amyloid plaques in the brain
This study tests a newer, shorter PET scan to see if it can detect amyloid plaques (sticky protein clumps linked to memory loss) as well as the standard scan. It may help diagnose cognitive problems with less time in the scanner.
Toronto, OntarioAges 18 years+ - NCT06786936Recruiting
Study of IL-17 in depression with psoriasis
This study explores whether a protein called IL-17 might link skin/joint inflammation with depressive symptoms. If you have psoriasis or psoriatic arthritis and are starting a specific biologic (secukinumab, bimekizumab, or ixekizumab), this could help understand how treatment affects your mood.
Glasgow, ScotlandAges 18–74 - NCT06788431RecruitingEarly Phase 1
Study of IMC-001 to stabilize heart artery plaque
This trial tests an investigational drug, IMC-001, to see if it can make artery plaques in the heart more stable and less likely to cause a heart attack. You may be eligible if you've recently had a heart attack or unstable angina and have a specific type of soft plaque in your arteries.
Nanyang, HenanAges 18–75
Hear when a new Plaque trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 181 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.