Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT07183111Recruiting
AI vs. regular instructions for braces patients
This trial compares standard instructions to AI-powered guidance (using a custom ChatGPT) to help patients with braces learn how to care for their teeth. It aims to see which method helps patients follow oral hygiene instructions better.
Islamabad, FederalAges 18–30 - NCT07180849Recruiting
New fluoride varnish vs standard varnish for braces plaque
This trial compares a new fluoride varnish that contains tiny titanium particles (nanoparticles) to a standard fluoride varnish. It tests which one is better at preventing plaque buildup for people getting braces.
IslamabadAges 16–30 - NCT07166731Recruiting
Carotid stent vs. medication for recent stroke risk
This trial tests if a carotid artery stent plus medication is better than medication alone at preventing another stroke in people who recently had a stroke or eye blockage caused by a non-narrowing but risky carotid plaque.
Solingen, North Rhine-WestphaliaAges 18 years+ - NCT07169201Recruiting
CT scan for heart in people with diabetes or heart disease
This study uses a special CT scan to look at your heart more closely. It may help people with known or suspected heart problems or type 2 diabetes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07116967RecruitingPhase 3
Long-term safety of two psoriasis drugs in people with heart risk
This study compares two medications for psoriasis (deucravacitinib and ustekinumab) over a long period. It's designed for people with moderate-to-severe psoriasis who also have certain risk factors for heart disease, like high blood pressure or diabetes.
Birmingham, AlabamaAges 40 years+ - NCT07104487RecruitingPhase 2
PET/MRI scan to detect inflammation in carotid artery disease
This study tests whether a special type of PET/MRI scan can help doctors see inflammation in the carotid artery after a stroke or mini-stroke. By using a radioactive tracer, the scan may identify which patients have dangerous plaque buildup that could lead to another stroke.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07030088Recruiting
Testing a new two-sided toothbrush for healthier gums
This trial tests a special toothbrush that cleans both sides of your teeth at once. It compares this new brush to a regular one to see if it improves gum health in dentists.
RiyadhAges 25–40 - NCT07029360Recruiting
Coenzyme Q10 and Probiotics for Gum Health in Pregnancy
This trial tests whether adding coenzyme Q10 and probiotics to standard gum treatment can improve gum health and reduce inflammation in pregnant women. If you are in your second or third trimester and have gum concerns, this treatment may help both you and your baby.
Pavia, LombardyAges 18 years+ - NCT06997055Recruiting
Study of Steqeyma® biosimilar in Crohn's and psoriasis
This study follows people with Crohn's disease or plaque psoriasis who are switching from the reference Ustekinumab to a biosimilar (Steqeyma®). It aims to see how well the biosimilar works in real-world settings.
AmiensAges 18 years+ - NCT06999941Enrolling by invitation
Study of deucravacitinib for psoriasis with eczema features
This trial tests an oral medication called deucravacitinib for people who have both psoriasis and eczema (or psoriasis that looks like eczema) on their skin. The goal is to see if it can help reduce the severity of their plaques and itch.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06980714Enrolling by invitation
Electric vs. manual toothbrush for advanced gum disease
This study compares electric and manual toothbrushes to see which one works better for people with advanced gum disease (stage 3 or 4 periodontitis). It might help you find a more effective way to care for your teeth and gums at home.
L’AquilaAges 18 years+ - NCT06786936Recruiting
Study of IL-17 in depression with psoriasis
This study explores whether a protein called IL-17 might link skin/joint inflammation with depressive symptoms. If you have psoriasis or psoriatic arthritis and are starting a specific biologic (secukinumab, bimekizumab, or ixekizumab), this could help understand how treatment affects your mood.
Glasgow, ScotlandAges 18–74 - NCT06902740RecruitingPhase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing
This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06896708Recruiting
Intensive cholesterol treatment for heart plaque in younger adults
This trial tests whether higher doses of cholesterol-lowering medication (statins) can slow down plaque buildup in the heart arteries of younger and middle-aged adults with stable chest pain. It may help prevent heart attacks and the need for procedures like stents.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT06754956Recruiting
MRI Study of Artery Plaques Using Different MRI Scanners
This study investigates the build-up of fatty deposits called plaques in arteries of the brain and neck using two different strengths of MRI scanners. It aims to understand how well these MRI techniques can image the plaques, which could help doctors better diagnose and manage stroke risk.
ShanghaiAges 18–95 - NCT06888193RecruitingPhase 1
Bimekizumab in breast milk of mothers being treated
This study measures how much bimekizumab (Bimzelx) gets into breast milk. It helps us understand if the medicine is safe for breastfeeding babies whose mothers take this drug.
Santa Monica, CaliforniaAges 18 years+ - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Phoenix, ArizonaAges 18 years+ - NCT06863545Recruiting
PCSK9 Inhibitors for High-Risk Coronary Plaques on CT
This study tests whether adding a PCSK9 inhibitor (a newer cholesterol-lowering shot) to standard treatment can reduce heart risks in people who have certain high-risk plaque features seen on a CT scan of their heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT06788431RecruitingEarly Phase 1
Study of IMC-001 to stabilize heart artery plaque
This trial tests an investigational drug, IMC-001, to see if it can make artery plaques in the heart more stable and less likely to cause a heart attack. You may be eligible if you've recently had a heart attack or unstable angina and have a specific type of soft plaque in your arteries.
Nanyang, HenanAges 18–75 - NCT06757569Recruiting
New PET scan for detecting amyloid plaques in the brain
This study tests a newer, shorter PET scan to see if it can detect amyloid plaques (sticky protein clumps linked to memory loss) as well as the standard scan. It may help diagnose cognitive problems with less time in the scanner.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.