Clinical trials
Pleural Mesothelioma clinical trials
Below are recruiting pleural mesothelioma clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07192900RecruitingPhase 1
Fast TILs for metastatic cancer with pleural disease
This trial tests a new therapy using your own immune cells (called TILs) to treat cancer that has spread to the lining of the lungs. The goal is to see if these cells can shrink tumors and help you feel better.
Pittsburgh, PennsylvaniaAges 18–79 - NCT06840834RecruitingPhase 2
New drug for mesothelioma that has returned after prior treatment
This trial tests a drug called ivonescimab for people with pleural mesothelioma (a cancer of the lung lining) that has grown back after earlier immunotherapy and chemotherapy. The drug may help by blocking a protein that tumors use to hide from the immune system, possibly slowing or shrinking the cancer.
BesançonAges 18 years+ - NCT03683680Recruiting
Collecting pleural tissue samples to study mesothelioma markers
This study collects tissue samples (from the lining around the lung) from adults with malignant pleural mesothelioma. Researchers will use these samples to check whether certain test markers can predict how the disease may behave, which could guide treatment decisions in the future.
Boston, MassachusettsAges 18 years+ - NCT06910449Recruiting
Radiation after lung lining surgery for spread cancer
This trial tests a type of radiation therapy (hemithoracic arc radiotherapy) for people whose cancer has spread beyond the lung and who have already had surgery to remove the lining of the lung. The goal is to see if this radiation helps control the disease.
Cairo, Fom ElkhaligAges 18 years+ - NCT05304208RecruitingPhase 1
Mesothelioma trial using immune cells plus surgery
This early-phase study tests a treatment that uses a patient’s immune cells (dendritic cell therapy) combined with surgery for epithelioid mesothelioma. It aims to help the immune system better recognize and attack the cancer after chemotherapy and before/around surgery.
Rotterdam, South HollandAges 18 years+ - NCT07443020RecruitingPhase 1
Fast immune cells for fluid build-up from cancer
This trial tests a treatment using your own immune cells (T cells) to fight cancer that has spread to the lining of the lung and is causing fluid buildup. It may help if other standard treatments have stopped working.
Pittsburgh, PennsylvaniaAges 18–79 - NCT06756035RecruitingPhase 1
Testing CT-95 in advanced cancers with mesothelin
This trial tests a new drug (CT-95) for advanced cancers that have a marker called mesothelin. It's an early-phase study to see if the drug is safe and effective.
Denver, ColoradoAges 18 years+ - NCT06946498Recruiting
Local anesthesia thoracoscopy for diagnosing unknown fluid around the lung
This study tests a newer, less invasive procedure to diagnose the cause of fluid buildup around the lung. It uses local anesthesia and a small camera to look inside the chest, which may make diagnosis faster and more comfortable.
Athens, AtticaAges 18–90 - NCT00242723Recruiting
Looking at cell changes in lung, esophagus, and chest cancers
This study collects blood, urine, and tissue samples from people with lung, esophageal, or other chest cancers to look at cell changes. It does not test a new treatment—instead, it aims to better understand these cancers through research.
Bethesda, MarylandAges 2–120 - NCT03917043RecruitingPhase 1
Testing a new targeted drug for ALK or ROS1 lung cancers
This Phase 1 trial tests APG-2449, a new drug, in people with advanced solid tumors—especially certain lung cancers that have ALK or ROS1 gene fusions. Because it’s an early safety-and-dose study, it may help learn how well the drug works and what doses are safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05628376Recruiting
Tracking lung cancer evolution through treatment
This study follows people with lung cancer over time to see how the disease changes, especially during and after treatment. By collecting tumor samples and blood tests every few months, researchers hope to understand why some cancers come back or become resistant, and find better ways to treat them.
LondonAges 18 years+ - NCT05086692RecruitingPhase 1/Phase 2
Beta-only IL-2 therapy for advanced solid tumors
This Phase 1/2 study tests a beta-only version of IL-2, an immune-stimulating treatment, to shrink or control advanced or metastatic solid tumors. It’s mainly designed to check safety and to see if it can help patients by improving tumor response.
San Diego, CaliforniaAges 18 years+ - NCT05107674RecruitingPhase 1
Early drug study for advanced cancers that have limited options
This Phase 1 study tests NX-1607 in adults with advanced cancers that are hard to treat with standard care. It focuses on safety and early signs of how well the drug may work in specific cancer types.
Duarte, CaliforniaAges 18 years+ - NCT06362369RecruitingPhase 1/Phase 2
Oral 7HP349 with immunotherapy for advanced solid tumors
This trial tests an experimental oral drug (7HP349) combined with two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced solid tumors. It aims to see if the combination is safe and effective in shrinking tumors.
Aurora, ColoradoAges 18 years+ - NCT06451536Recruiting
Special PET Scan Before Immunotherapy for Mesothelioma
This trial uses a special PET scan (called Ga-68 FAPI) to see if it can help doctors better plan or monitor immunotherapy for people with pleural mesothelioma. It may help doctors predict how well the treatment will work.
AnkaraAges 18 years+ - NCT06535607RecruitingPhase 2
Study of volrustomig for advanced solid tumors
This trial tests a new drug called volrustomig, alone or with other cancer treatments, for people with advanced or metastatic solid tumors. It aims to see if the drug can help shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT07403630Recruiting
Tumor chemogenomic profiler for cancer patients of all ages
This trial uses a new testing platform to analyze the genes and proteins in your tumor, aiming to find the most effective treatments for people with cancer that has come back, is not responding to treatment, or has spread. It is designed for both children and adults with any type of blood cancer or solid tumor.
Palermo, PalermoAges 1 year+ - NCT07532902RecruitingPhase 1
Testing an experimental drug with standard care for solid tumors
This trial tests a new drug (BMS-986504) combined with standard chemotherapy or immunotherapy for three types of advanced solid tumors: mesothelioma, gastroesophageal cancer, or bladder cancer. It may be an option if your tumor has a specific genetic change called MTAP deletion.
Basking Ridge, New JerseyAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for pleural mesothelioma?
- Yes. Clin2 currently lists 44 recruiting pleural mesothelioma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pleural mesothelioma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pleural mesothelioma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.