Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 539 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07577869Recruiting
Nerve blocks for pain relief after knee replacement
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Kayseri, KocasinanAges 18–80 - NCT07571252RecruitingPhase 4
Pain Relief Before Jaw Surgery: A Study
This study tests whether taking pain medicine before jaw surgery (orthognathic surgery) helps reduce pain after the procedure. If you're having jaw surgery, this trial may help doctors understand the best way to manage your pain.
San JuanAges 21–65 - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65 - NCT07382297Recruiting
Knee tumor pain study with extra nerve block
This study tests if adding an ultrasound-guided nerve block (IPACK) behind the knee to a standard nerve block (adductor canal block) can better control pain after knee tumor surgery. If you are having knee tumor removal and are in fair to poor health, this may help improve your recovery.
CairoAges 18–65 - NCT07360392Recruiting
Nerve block comparison for knee replacement pain
This study compares two numbing techniques (nerve blocks) for pain relief after knee replacement surgery. The goal is to find which one works better and helps you recover with less pain.
AmasyaAges 18–80 - NCT07147049RecruitingPhase 2
Testing a new painkiller for moderate to severe pain after surgery
This trial tests a new tablet called HL-1186 for people with moderate to severe pain after certain surgeries. It aims to see if the drug is safe and works well for pain control.
Chengdu, SichuanAges 18–75 - NCT06845215Recruiting
Pain block comparison for abdominoplasty recovery
This trial compares two types of nerve blocks (TAP and ESP) to see which provides better pain relief after tummy tuck surgery. Both are injections near the abdominal muscles that numb the area, and you'll also have a patient-controlled pain pump.
Ankara, KeçiörenAges Any age - NCT03858231RecruitingPhase 4
Opioid vs non-opioid pain relief after knee arthroscopy
This study compares opioid pain medicine with non-opioid pain medicine after arthroscopic (keyhole) knee surgery. It aims to see which approach controls pain well while keeping side effects and risks lower.
Fargo, North DakotaAges 18–80 - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07833930Recruiting
Breakthrough pain after arm numbing block in diabetic patients
This study looks at whether people with diabetes have more breakthrough pain (pain that breaks through despite the block) within 48 hours after an arm surgery with a specific type of nerve block. The goal is to understand and improve pain management for diabetic patients.
TaiyuanAges 18–80 - NCT07731295Recruiting
Pain management study for teens getting wisdom teeth removed
This study looks at how to improve pain management after wisdom tooth extraction. It focuses on teens and young adults who use cannabis regularly, to see how it affects pain and recovery.
Providence, Rhode IslandAges 15–20 - NCT07707401Recruiting
WeChat neck exercises for recovery after thyroid surgery
This study tests whether simple neck exercises, guided through the WeChat app, can help you recover more quickly after thyroid surgery. If you have no serious complications and don't have neck problems, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07689461Recruiting
Virtual reality for pain after hip replacement
This trial tests if using virtual reality can help reduce pain after hip replacement surgery. It may be a good option if you are having a hip replacement and have moderate to severe pain.
MalatyaAges 18–99 - NCT07547774Recruiting
Sleep Quality Before Breast Surgery and Recovery Outcomes
This study examines how well you sleep before breast cancer surgery and whether it affects your recovery afterward. Researchers will ask about your sleep habits and track your healing to understand the connection.
Ankara, YenimahalleAges 18–70 - NCT07541040Recruiting
Nerve Blocks for Breast Surgery Pain Relief
This trial tests two different nerve-block techniques to reduce pain after breast surgery. The study compares a serratus block with an ESP block—both are injections of numbing medication near nerves—to see which works better for managing pain without heavy opioid use.
İzmit, KocaeliAges 18–65 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07482709RecruitingPhase 1/Phase 2
Nerve block with or without ketamine for hysterectomy pain
This study compares two ways to reduce pain after a hysterectomy: a standard nerve block with bupivacaine (a numbing medicine) versus the same block plus ketamine (a medicine that can boost pain relief). The goal is to see if adding ketamine provides better comfort after surgery.
Karachi, SindhAges 25–65 - NCT07357233Recruiting
Comparing two methods for root canal pain relief in lower molars
This trial compares two different ways of cleaning and shaping the inside of a tooth (root canal) to see which one causes less pain afterward. It is for people with a specific type of tooth infection in a lower back molar.
AlexandriaAges 18–50 - NCT07307703Recruiting
TENS for pain and anxiety after gallbladder surgery
This trial tests whether TENS, a mild electrical therapy, can reduce pain and anxiety after gallbladder removal. If you are having planned gallbladder surgery and are in good health, you may be able to participate.
Niğde, AdanaAges 18 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07229495RecruitingPhase 4
Tegileridine for pain after scoliosis surgery in teens
This trial tests a new pain medicine, tegileridine, for teenagers having spine surgery for scoliosis. It aims to see if it controls pain well after the operation, and if it's safe.
Zhengzhou, HenanAges 10–17 - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years
Hear when a new Postoperative Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 539 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.