Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 538 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07619651Recruiting
Pain relief methods after hypospadias repair in young boys
This trial compares two different numbing techniques to help manage pain after hypospadias surgery (a procedure to correct the urinary opening in boys). The goal is to find which method works better and is safer for young children.
KayseriAges 6 months–7 years - NCT07612761Recruiting
Pain Relief Methods for Hip Fracture Surgery
This trial compares two different nerve-blocking techniques to help manage pain after hip fracture surgery. Both methods numb the area around your hip to reduce pain and may help you recover better.
Istanbul, IstanbulAges 18 years+ - NCT03596424Recruiting
Testing ketamine and dexmedetomidine during lung surgery
This trial studies whether the anesthesia medicines ketamine and dexmedetomidine can improve care during elective lung (video-assisted) surgery. It may help with comfort during and after the operation, depending on how these medicines affect pain and recovery.
Montreal, QuebecAges 18–80 - NCT07603934RecruitingEarly Phase 1
Testing Medications Inside Root Canals to Reduce Pain
This study tests different medications placed inside a tooth's root canal during treatment to see which one best reduces pain afterward. If you have a tooth with a dead nerve (necrotic pulp), this trial might help determine the best way to manage your pain during the healing process.
Cairo, Cairo GovernorateAges 18–40 - NCT07608939Recruiting
Pain relief after root canal treatment with different sealers
This study compares how much pain you experience after root canal treatment depending on which type of sealing material is used. Root canal treatment removes infected tissue from inside a tooth; this trial helps dentists find the approach that causes the least post-treatment discomfort.
LefkaAges 18–60 - NCT07603921Recruiting
Local Pain Relief Injection During Lung Surgery
This study tests whether injecting a numbing medicine and anti-inflammatory steroid around the surgical area before lung surgery reduces pain after the procedure. If it works, it could help patients recover more comfortably after thoracoscopic lung surgery (minimally invasive lung surgery using small cameras).
Beijing, Beijing MunicipalityAges 18–64 - NCT07599254RecruitingPhase 4
Pain Relief After Root Canal Retreatment
This study tests two different ways of cleaning and treating a tooth that had a root canal treatment before. Researchers want to see which method causes less pain after the procedure.
KayseriAges 18–60 - NCT07590752RecruitingPhase 2/Phase 3
Pain Relief Comparison for Abdominal Surgery
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
Sahiwal, Punjab ProvinceAges 25–65 - NCT07591233Recruiting
Pain Relief Injection During Laparoscopic Surgery
This trial tests whether injecting a numbing medication mixed with a steroid into the surgical area before making cuts can reduce pain after common laparoscopic procedures like gallbladder removal or hernia repair. The goal is to help patients recover with less pain and fewer pain medications.
Beijing, Beijing MunicipalityAges 18–64 - NCT07591207Recruiting
Pain relief patch after laparoscopic abdominal surgery
This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–64 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07585721Recruiting
Pain Relief After Root Canal Treatment: Two Different Medications
This study compares two types of medications placed inside a tooth after root canal treatment to see which one reduces pain better. You'll be asked about your pain levels after treatment, and researchers will measure a pain-related substance in your saliva.
CairoAges 18–45 - NCT07577154Recruiting
Brain-Monitoring Anesthesia for Pediatric Throat Surgery
This trial tests a special brain-monitoring device (called Conox) during anesthesia for children having their tonsils and adenoids removed. The goal is to help doctors give the right amount of anesthetic medicine by watching your child's brain activity in real time.
KayseriAges 3–12 - NCT06479161RecruitingPhase 2
Oral tranexamic acid study for knee replacement patients
This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.
Hartford, ConnecticutAges 18–89 - NCT06191159Recruiting
Comparing scar looks after different mastectomy incision methods
This trial compares three different ways surgeons make the incision (cut) during a mastectomy to see which one leads to the best-looking scar. You may be eligible if you are having a mastectomy without immediate reconstruction.
Vancouver, British ColumbiaAges Any age - NCT07561333Recruiting
Pain Relief Methods for Knee Replacement Surgery
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
Çorum, CentreAges 18–80 - NCT07561853Recruiting
Nerve block comparison for pain relief after mastectomy
This study compares two different numbing treatments (nerve blocks) to see which provides better pain relief during and after breast surgery. If you are having a mastectomy, this trial may help reduce your pain after the operation.
SakaryaAges 25–65 - NCT07566663Recruiting
Pain Relief Before Gallbladder Removal Surgery
This study tests whether a pain-relief medication called Anrikefon, given before laparoscopic gallbladder removal surgery, helps reduce pain after the procedure. Laparoscopic surgery uses small cuts and a camera, so it's less invasive than open surgery.
Beijing, Beijing MunicipalityAges 18–65 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT07519109RecruitingPhase 1
SYH9089 for pain after abdominal surgery
This study tests an injected medicine (SYH9089) to see if it safely controls pain after abdominal surgery. It may help you recover with less discomfort.
Changsha, HunanAges 18–75 - NCT07524673Recruiting
Comparing two nerve blocks for chest surgery pain
This study tests two different numbing techniques (nerve blocks) to see which one works better for pain relief after minimally invasive chest surgery. Both methods inject medicine near nerves to reduce post-surgery pain.
Sivas, MerkezAges 18 years+
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 538 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.