Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 561 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07215780Recruiting
Sitz baths after pelvic organ prolapse surgery
This study compares sitz baths to regular care after surgery for pelvic organ prolapse. It aims to see if sitz baths can help reduce pain and improve recovery. If you are having prolapse repair surgery, you may be able to join.
Bridgeport, ConnecticutAges 18 years+ - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT07410780Recruiting
Pain after root canal with two different sealers
This trial compares two types of root canal filling materials—bioceramic and calcium hydroxide—to see which one causes less pain after the procedure. If you have a tooth with a live but inflamed nerve, you may be able to join.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT06633068RecruitingPhase 2
Pain relief study: nalbuphine added to numbing medicine for thyroid surgery
This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.
Giza, الجيزةAges 18–60 - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07626463Recruiting
Local anesthetic injection to reduce pain after laparoscopic surgery
This trial tests whether injecting a local anesthetic (numbing medicine) and a steroid around the surgical area before surgery reduces pain after laparoscopic procedures like gallbladder, appendix, or hernia repair. The goal is to help patients recover more comfortably with potentially less pain medication needed.
Beijing, Beijing MunicipalityAges 18–64 - NCT07603921Recruiting
Local Pain Relief Injection During Lung Surgery
This study tests whether injecting a numbing medicine and anti-inflammatory steroid around the surgical area before lung surgery reduces pain after the procedure. If it works, it could help patients recover more comfortably after thoracoscopic lung surgery (minimally invasive lung surgery using small cameras).
Beijing, Beijing MunicipalityAges 18–64 - NCT07411521Recruiting
Comparing two pain relief methods after planned cesarean
This trial compares two ways to manage pain after a planned cesarean section: one combines a spinal and epidural injection, the other is a newer type of nerve block. The goal is to see which provides better pain relief with fewer side effects.
Bursa, NilüferAges 18–45 - NCT07231926Recruiting
Spinal morphine for recovery after keyhole lung surgery
This trial tests whether giving a small dose of morphine into the fluid around the spinal cord (intrathecal) can improve pain relief and recovery after keyhole lung surgery. It aims to help patients feel better faster and have fewer complications.
ErzurumAges 18–70 - NCT07141459Recruiting
Laser disinfection for failed root canal treatment
This trial tests if using a special laser (810 nm diode) to disinfect the tooth after a second root canal treatment can reduce pain and inflammation. It aims to help patients whose previous root canal failed and who have a small infection around the tooth root.
CairoAges 20–40 - NCT07743736Recruiting
Aromatherapy and massage after cesarean delivery
This trial tests whether aromatherapy and massage help new mothers recover after a cesarean birth. It may reduce pain and improve well-being after delivery.
Uşak, UşakAges 18–40 - NCT06067893Enrolling by invitationPhase 4
Low dose sedation medicine for pain after scoliosis surgery
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Kansas City, MissouriAges 10–21 - NCT05833048Recruiting
Pain-relief nerve block during cardiac surgery
This study tests whether a numbing “nerve block” placed in the rectus sheath area can reduce pain for people having certain heart surgeries with chest tubes. If you qualify, it may help your comfort during recovery, but it also depends on how suitable you are for local anesthesia.
New York, New YorkAges 18–85 - NCT07716566Recruiting
Nerve block for pain after kidney transplant
This trial tests a nerve block called a quadroiliac plane block to see if it helps control pain after kidney transplant surgery. If you are having a kidney transplant, this study might help reduce your pain and need for pain medication.
Istanbul, IstanbulAges 18–80 - NCT07733128Recruiting
Pain relief with buprenorphine patch after lung surgery
This study tests a skin patch that releases buprenorphine, a pain medicine, to control pain after lung surgery. It may help reduce pain and the need for other pain medicines.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT07426796Recruiting
Comparing two pain blocks for pediatric testicle surgery
This trial compares two types of numbing injections for pain after surgery to fix an undescended testicle in young boys. It aims to find which injection works better for comfort during recovery.
IstanbulAges 1–7 - NCT07426731Recruiting
Comparing two pain blocks for hypospadias surgery in boys
This trial tests two different ways to numb the area for hypospadias repair surgery in young boys. It aims to find which method works better to manage pain after the operation.
IstanbulAges 1–7 - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT07188779RecruitingPhase 2
Impact of a special gel on tonsillectomy recovery in children
This trial tests whether applying a special gel called RADA16 to the surgical site after tonsillectomy (removal of tonsils) can help children heal better and with less pain. It may offer a new way to improve recovery after this common surgery.
Livingston, New JerseyAges 3–17 - NCT07603934RecruitingEarly Phase 1
Testing Medications Inside Root Canals to Reduce Pain
This study tests different medications placed inside a tooth's root canal during treatment to see which one best reduces pain afterward. If you have a tooth with a dead nerve (necrotic pulp), this trial might help determine the best way to manage your pain during the healing process.
Cairo, Cairo GovernorateAges 18–40 - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120 - NCT07519109RecruitingPhase 1
SYH9089 for pain after abdominal surgery
This study tests an injected medicine (SYH9089) to see if it safely controls pain after abdominal surgery. It may help you recover with less discomfort.
Changsha, HunanAges 18–75 - NCT03037684Recruiting
Electrical skin stimulation for nerve and chronic pain
This trial tests whether painless electrical stimulation through the skin can reduce neuropathic pain or long-lasting pain after surgery. It may help some people by changing how pain signals travel in the nervous system.
NottwilAges 18–65
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 561 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.