Clinical trials
Primary Hypertension clinical trials
Below are recruiting primary hypertension clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85 - NCT07310719Recruiting
Comparing laser versus eye drops for new glaucoma patients
This trial compares two first treatments—laser therapy (SLT) or daily eye drops (latanoprost)—to lower eye pressure in people newly diagnosed with open-angle glaucoma or high eye pressure. It aims to find which approach works better as an initial therapy.
Ikeja, LagosAges 18–90 - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT07228065Enrolling by invitation
Combination pill study for better blood pressure control
This trial tests whether switching to a single pill that combines two blood pressure medicines helps control high blood pressure better than taking two separate pills. It might make treatment simpler and more effective.
Milwaukee, WisconsinAges 18–80 - NCT05917275RecruitingPhase 4
Testing tests to predict how you’ll respond to blood pressure medicines
This study uses blood and other body measurements to predict how well certain blood pressure medicines will work for you. It may help doctors choose the best treatment sooner, based on your personal “multi-omics” (biomarker) results.
NijmegenAges 18–75 - NCT07192783Recruiting
Lavender inhalation for anxiety, sleep, and blood pressure
This study tests whether inhaling lavender aroma can help lower anxiety, improve sleep, and reduce blood pressure in people with high blood pressure. It is a simple, non-drug approach that you can try at home.
Ardahan, ArdahanAges Any age - NCT07181213Enrolling by invitation
Genetic links to high blood pressure
This trial is for people who took part in a large study (SCAPIS) and have both a certain genetic trait and high blood pressure. The goal is to understand how your genes may affect blood pressure.
Linköping, Östergötland CountyAges 50 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT07693699Recruiting
Helping with home blood pressure monitoring in primary care
This study provides support for getting and using a home blood pressure monitor if you have high blood pressure. It tests a training pathway to help you track your blood pressure at home.
Chicago, IllinoisAges 18 years+ - NCT07045623Recruiting
Better care and education for high cholesterol
This study compares two ways of managing high cholesterol: a more intensive program with extra support versus the usual care and education. It's for people with high blood pressure or diabetes who are already part of a community health program.
Gyeonggi-do, Suwon-siAges 30–80 - NCT07540143Recruiting
Blood pressure management program for young women
This study tests a program to help women aged 18–44 with high blood pressure who are taking blood pressure medication. The program uses phone and internet tools to help you manage your blood pressure better at home.
Chicago, IllinoisAges 18–44 - NCT06549673Recruiting
Stopping beta blocker in controlled cirrhosis
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
SydneyAges 18 years+ - NCT06523465RecruitingPhase 4
Statin plus amlodipine for primary aldosteronism
This trial tests whether combining a statin (usually for cholesterol) with amlodipine (a blood pressure medication) can better treat primary aldosteronism, a hormonal condition that causes high blood pressure. If you have this condition, this study may offer a new way to manage it.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06310148Recruiting
Preventing chronic disease in Hong Kong adults aged 45+
This study looks at a new program in Hong Kong that helps people without diabetes or hypertension learn how to prevent or manage chronic diseases. One group gets extra support through a local health centre, and the other group follows usual care.
Hong KongAges 45 years+ - NCT06465537Recruiting
Gene editing therapy for glaucoma with MYOC mutation
This trial is testing a one-time gene-editing treatment for people with glaucoma caused by a MYOC gene mutation. The goal is to lower eye pressure and possibly reduce the need for eye drops.
Beijing, Beijing MunicipalityAges 18–65 - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT07598669Recruiting
Austrian Primary Biliary Cholangitis Registry Study
This is a registry study that collects health information from people with primary biliary cholangitis (PBC), a rare liver disease where the immune system damages bile ducts. By joining, you help researchers better understand PBC and improve care for patients with this condition.
Klagenfurt, CarinthiaAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT06947460RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant lupus, sclerosis, and Sjögren's lung disease
This trial tests a special immune cell therapy (CAR-T cells targeting CD19 and BCMA) for people with lupus nephritis, systemic sclerosis, or Sjögren's-related lung blood vessel disease that hasn't improved with usual treatments. The goal is to see if this one-time cell infusion can calm the overactive immune system and improve symptoms.
Beijing, China,BeijingAges 10–65
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Common questions
- Are there clinical trials for primary hypertension?
- Yes. Clin2 currently lists 58 recruiting primary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.