Clinical trials
Primary Hypertension clinical trials
Below are recruiting primary hypertension clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04808596Recruiting
Pulmonary hypertension registry and blood sample study
This study builds a registry and collection system for people with pulmonary hypertension, confirmed by a specific heart test. By joining, you help researchers learn more about the condition and may support future studies.
Kansas City, KansasAges 18 years+ - NCT07236125Recruiting
Nitrate-rich foods and mouth bacteria in children with high blood pressure
This study looks at how eating nitrate-rich vegetables (like spinach and beets) might affect the helpful bacteria in your child's mouth and their blood pressure. It's for children ages 10 to 18 who have primary hypertension (high blood pressure not caused by another condition) and are otherwise healthy.
Istanbul, FatihAges 10–18 - NCT06646354Enrolling by invitationPhase 3
Study of two experimental drugs for high blood pressure and cholesterol
This trial tests whether taking two experimental drugs together can safely lower both high blood pressure and high cholesterol. It may be an option if you have both conditions and your blood pressure is not extremely high.
SeoulAges 19 years+ - NCT07728643Recruiting
Blood vessel particles in children with new high blood pressure
This study looks at tiny particles in the blood (called extracellular vesicles) that may signal early blood vessel changes in children with new high blood pressure. If your child is between 6 and 17, has just been diagnosed with high blood pressure and hasn't started treatment, and is otherwise healthy, this trial may help doctors better understand how high blood pressure affects kids.
OsijekAges 6–17 - NCT03388476Enrolling by invitation
Breathing carbon dioxide measurement to detect lung high blood pressure
This trial tests whether measuring carbon dioxide you breathe out can help detect pulmonary hypertension earlier. It may help doctors spot this lung blood vessel condition sooner, especially around the time you get a heart test.
Giessen, HesseAges 18 years+ - NCT07607275RecruitingPhase 4
Chinese herbal medicine for managing high blood pressure
This trial tests whether a traditional Chinese herbal medicine called Yufeng Ningxin can help lower blood pressure in adults with newly diagnosed or ongoing high blood pressure. Researchers will measure how well it works compared to standard treatment.
BeijingAges 18–65 - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Phoenix, ArizonaAges 18 years+ - NCT07307924Enrolling by invitation
Can motivational talks help with high blood pressure?
This study tests whether talking with a health coach (motivational interviewing) can help people with high blood pressure better understand their condition, feel more confident managing it, and stick with their treatment. It focuses on people living in semi-rural areas.
Kütahya, Kütahya/ SimavAges 25–59 - NCT07383220Recruiting
Electrical stimulation and exercise for resistant high blood pressure
This trial tests if adding electrical stimulation to exercise can improve blood flow in people with resistant high blood pressure. It may help those whose blood pressure stays high despite taking multiple medications.
Port Said, Port Said GovernorateAges 50–60 - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT07051811Recruiting
Blood vessel treatment for hard-to-control high blood pressure
This trial tests a new device that uses ultrasound to treat nerves in the kidney arteries that may be overactive and raising your blood pressure. It's for people whose blood pressure stays high despite taking at least two medications.
Beijing, Beijing MunicipalityAges 18–75 - NCT07470580Recruiting
Heat treatment vs surgery for adrenal gland tumor
This study compares two treatments for a certain type of adrenal gland tumor (Conn's adenoma) that causes high blood pressure. One is a heat-based procedure called radiofrequency ablation and the other is surgery to remove the tumor. The goal is to see which is better at controlling blood pressure.
ToulouseAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT04409431Recruiting
Spironolactone plus adrenal nerve treatment for adrenal overactivity
This trial studies whether blocking part of the adrenal blood supply (“adrenal artery ablation”) along with spironolactone can improve hormone-driven high blood pressure caused by primary aldosteronism. It may help people who have confirmed adrenal overactivity and do not want surgery.
Chongqing, Chongqing MunicipalityAges 30–60 - NCT06941116Recruiting
Steroid test to screen for a common cause of high blood pressure
This trial tests whether a simple steroid-based test can help identify a specific type of high blood pressure called primary aldosteronism. If you have high blood pressure that needs medication, this study may help find a treatable cause.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07137364Recruiting
Testing spironolactone with blood pressure drugs for PA
This trial looks at whether adding spironolactone to your current blood pressure medicines works better for people with primary aldosteronism (a condition where your adrenal glands make too much aldosterone, raising blood pressure). You may qualify if you have this form of high blood pressure but have declined surgery or don't have an adenoma.
Chongqing, Chongqing MunicipalityAges 30–65 - NCT06769269Recruiting
Hypertension registry study in Morocco
This study is creating a registry of people with high blood pressure in Morocco. It aims to understand different types of hypertension, related health problems, and how to personalize treatment.
Meknes, MoroccoAges 18 years+ - NCT06580613Recruiting
Better blood pressure management in primary care
This trial tests a new way to manage high blood pressure in primary care. It aims to help people better control their blood pressure using home monitoring and digital tools.
HelsingborgAges Any age - NCT07361276Recruiting
Observational study on high blood pressure treatment in public clinics
This study looks at how doctors treat high blood pressure in public health clinics. By reviewing medical records, researchers hope to understand what treatments are used and how well they work.
FlorianópolisAges 18 years+ - NCT06740838Recruiting
Overnight dexamethasone test for aldosterone screening
This trial is testing a new way to screen for a hormone problem called primary aldosteronism (which can cause high blood pressure) by giving a steroid pill (dexamethasone) overnight. You may be eligible if you have high blood pressure and an adrenal growth, and are already scheduled for a related hormone test.
Gdansk, Pomeranian VoivodeshipAges 40–75 - NCT06569589Recruiting
Sodium MRI for primary aldosteronism
This study uses a special MRI to measure sodium levels in your body to better understand and treat primary aldosteronism, a condition that can cause hard-to-control high blood pressure. Participating may help doctors learn how to manage your condition more effectively.
SingaporeAges 21–70 - NCT07688928Recruiting
Finerenone vs spironolactone for high blood pressure from aldosteronism
This trial compares two medicines, finerenone and spironolactone, to see which works better and is safer for lowering blood pressure in people with primary aldosteronism. It may help you if you have high blood pressure caused by too much aldosterone.
DhakaAges 18 years+ - NCT07027254Recruiting
Can a special PET scan improve surgery for primary aldosteronism?
This study uses a new type of PET scan (called Gallium-68 Pentixafor PET-CT) to help doctors better identify the source of a hormone problem causing high blood pressure. The goal is to see if this scan leads to better surgical outcomes compared to standard methods.
Seoul, Gangnam-guAges 19 years+ - NCT06228677Recruiting
Catecholamine levels during adrenal artery embolization
This trial measures hormone levels in blood during a procedure to treat high blood pressure caused by an adrenal gland problem. It may help doctors understand how the body responds during treatment.
Chengdu, SichuanAges 18 years+
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Common questions
- Are there clinical trials for primary hypertension?
- Yes. Clin2 currently lists 58 recruiting primary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.