Clinical trials
Pulmonary Hypertension (Diagnosis) clinical trials
Below are recruiting pulmonary hypertension (diagnosis) clinical trials, each written for real people, not researchers. We’re tracking 119 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT04031508Enrolling by invitationPhase 2
Omega-3 in an IV for newborns with breathing circulation problems
This trial tests whether giving an omega-3 fat medicine through an IV (along with standard care) improves breathing and blood-flow problems in newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension. It may help reduce strain on the lungs and heart by targeting inflammation and blood-vessel changes.
Mexico City, Mexico CityAges 1 hour–2 weeks - NCT03980717Recruiting
Balloon procedure for severe congenital diaphragmatic hernia in pregnancy
This trial tests whether placing a tiny balloon in the fetus’s windpipe can help lungs develop and improve severe pulmonary (lung) blood pressure in babies with severe congenital diaphragmatic hernia (CDH). It may lower the chance of breathing and circulation problems after birth, but it requires a specialized procedure and close follow-up in Houston.
Houston, TexasAges 18–45 - NCT07816185RecruitingPhase 3
Inhaled study drug for pulmonary hypertension with lung scarring
This study tests an inhaled medication called mosliciguat for people with pulmonary hypertension (high blood pressure in the lungs) caused by certain types of lung scarring. It may help improve your ability to exercise and manage symptoms.
Kissimmee, FloridaAges 18–85 - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07143539Recruiting
Early exercise rehab after hospital stay for pulmonary embolism
This study tests if starting a supervised exercise program early after a hospital stay for a blood clot in the lungs (pulmonary embolism) helps patients recover better and feel less breathless. It is for people at higher risk of ongoing symptoms after their clot.
AarauAges 18 years+ - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT06941441RecruitingPhase 3
Exercise and medicine study for pulmonary arterial hypertension
This trial tests whether adding the study drug sotatercept to your current PAH therapy along with a home exercise program can help you feel better and be more active. It's for people with certain types of PAH who are stable on their current treatment.
Seattle, WashingtonAges 18 years+ - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Scottsdale, ArizonaAges 18–100 - NCT06605794Recruiting
FreeFlow heart shunt for severe idiopathic pulmonary hypertension
This trial tests a new device called FreeFlow, which creates a small opening in the wall between the top chambers of the heart to relieve pressure. It is for people with severe idiopathic pulmonary hypertension who still have serious symptoms despite standard medications.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06549452Recruiting
Mobile health app to help teens with pulmonary hypertension exercise
This trial tests whether a smartphone app can help adolescents with pulmonary hypertension stay active and improve their health. If you are a teen with stable PH and can use an activity tracker, this study may be a good fit.
Nashville, TennesseeAges 10–21 - NCT06350032RecruitingPhase 3
Testing treprostinil safety in children with PAH
This trial tests a medicine called treprostinil in children with severe pulmonary arterial hypertension (high blood pressure in the lungs). The study aims to see if it is safe and tolerable for kids who need this kind of therapy.
Vienna, State of ViennaAges Up to 18 years - NCT06317805RecruitingPhase 4
Three-medicine start vs. two oral pills for new PAH
This study compares starting treatment with three medicines, including a continuous infusion (treprostinil), versus two oral medicines for people newly diagnosed with moderate-to-high risk pulmonary arterial hypertension (PAH). The goal is to see which approach improves heart function and symptoms more effectively.
LinzAges 18–70 - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07623525RecruitingPhase 1/Phase 2
DIAG723 study for hereditary hemorrhagic telangiectasia
This study tests a new drug called DIAG723 in adults with hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and bleeding. Depending on which part of the study you qualify for, the drug may help reduce nosebleeds, improve anemia, or help with lung blood vessel problems caused by HHT.
Camperdown, New South WalesAges 18 years+ - NCT07613099RecruitingPhase 3
Testing a new PET scan to detect lung and heart scarring
This study tests a new imaging scan (called 18F-FAPI PET/CT) that may help detect scarring in the lungs, heart, or blood vessels. If you have a heart, lung, or blood vessel condition that could cause scarring, this scan might show damage earlier and help doctors plan better treatment.
Bethesda, MarylandAges 18–100 - NCT07724197Recruiting
Using a new imaging test to find blood clots in the lungs
This study tests a new, non-invasive imaging method called pulsatile electrical impedance tomography (EIT) to help diagnose and monitor acute pulmonary embolism (blood clots in the lungs). It may provide a faster or safer way to detect clots compared to standard CT scans, especially for patients who cannot have contrast dye.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07057648Recruiting
Robot-assisted lung biopsy for lung nodules in South Korea
This trial uses a robot-assisted bronchoscope to take tissue samples from lung nodules. It may help diagnose lung cancer or other conditions without major surgery.
UlsanAges 19 years+ - NCT05841615Recruiting
Atrial fibrillation and high blood pressure ablation plus kidney nerve treatment
This trial tests whether treating atrial fibrillation with a catheter procedure plus treating high blood pressure through kidney nerve treatment works better together. It may help control rhythm and blood pressure, but you must meet several heart, kidney-artery, and safety requirements.
Xiamen, FujianAges 18–75 - NCT06962436Recruiting
Comparing Robotic vs. Ultrathin Bronchoscopy for Lung Nodules
This trial compares two types of bronchoscopy (thin-tube lung camera) methods to see which one better samples lung nodules. You may be able to join if you have a suspicious lung nodule and need a biopsy.
Jinan, ShandongAges 18 years+ - NCT07648082Recruiting
Understanding Breathlessness in Lung Disease
This study explores how people experience and perceive breathlessness, whether they have a known lung condition or are healthy. Researchers want to understand breathlessness better to potentially improve how it's managed and treated.
Leicester, LeicestershireAges 18–100 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT05952999Enrolling by invitation
Studying Hospital-At-Home care done from home
This trial looks at how well a “Hospital at Home” program works when people start from the emergency department or are already in the hospital and can be cared for at home. It may help teams improve care at home for certain medical conditions and situations.
Peoria, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for pulmonary hypertension (diagnosis)?
- Yes. Clin2 currently lists 119 recruiting pulmonary hypertension (diagnosis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension (diagnosis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension (diagnosis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Hypertension
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Embolism (Diagnosis)
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.