Clinical trials
Pulmonary Hypertension clinical trials
Below are recruiting pulmonary hypertension clinical trials, each written for real people, not researchers. We’re tracking 247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03149341Enrolling by invitation
MRI and computer-heart simulations for heart disease
This study uses MRI scans and computer simulations to learn more about how the heart and blood flow work in people with certain heart or lung conditions. It may help researchers better understand heart problems and improve future care.
Palo Alto, CaliforniaAges Any age - NCT06544148Recruiting
Measuring lung artery pressure with a chest belt in ICU patients
This study tests a new way to measure blood pressure in your lung artery using a special belt that sends small electrical signals through your chest. It may help doctors monitor your heart and lungs without extra invasive procedures.
BernAges 18 years+ - NCT06317805RecruitingPhase 4
Three-medicine start vs. two oral pills for new PAH
This study compares starting treatment with three medicines, including a continuous infusion (treprostinil), versus two oral medicines for people newly diagnosed with moderate-to-high risk pulmonary arterial hypertension (PAH). The goal is to see which approach improves heart function and symptoms more effectively.
LinzAges 18–70 - NCT06476470Recruiting
Taiwan ILD registry for understanding lung disease
This registry is gathering information from people with different types of interstitial lung disease (ILD) across Taiwan. It aims to better understand the disease and improve future care.
TaichungAges 18 years+ - NCT06605794Recruiting
FreeFlow heart shunt for severe idiopathic pulmonary hypertension
This trial tests a new device called FreeFlow, which creates a small opening in the wall between the top chambers of the heart to relieve pressure. It is for people with severe idiopathic pulmonary hypertension who still have serious symptoms despite standard medications.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07623525RecruitingPhase 1/Phase 2
DIAG723 study for hereditary hemorrhagic telangiectasia
This study tests a new drug called DIAG723 in adults with hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and bleeding. Depending on which part of the study you qualify for, the drug may help reduce nosebleeds, improve anemia, or help with lung blood vessel problems caused by HHT.
Camperdown, New South WalesAges 18 years+ - NCT07613099RecruitingPhase 3
Testing a new PET scan to detect lung and heart scarring
This study tests a new imaging scan (called 18F-FAPI PET/CT) that may help detect scarring in the lungs, heart, or blood vessels. If you have a heart, lung, or blood vessel condition that could cause scarring, this scan might show damage earlier and help doctors plan better treatment.
Bethesda, MarylandAges 18–100 - NCT04062565RecruitingPhase 3
Testing treprostinil plus riociguat for advanced pulmonary artery hypertension
This study tests whether taking injected treprostinil together with riociguat can improve how the heart and lung blood vessels work in people with advanced pulmonary artery hypertension (PAH). It may help improve blood-flow measurements and the structure of the heart.
Tucson, ArizonaAges 18 years+ - NCT06865118Recruiting
Home management of heart issues in scleroderma
This study tests whether people with systemic sclerosis (scleroderma) and pulmonary arterial hypertension (PAH) can safely monitor their heart health at home using a smartphone or other internet-connected device. If you have PAH and are comfortable using technology, this trial may help make care more convenient.
OsloAges 18 years+ - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT06941441RecruitingPhase 3
Exercise and medicine study for pulmonary arterial hypertension
This trial tests whether adding the study drug sotatercept to your current PAH therapy along with a home exercise program can help you feel better and be more active. It's for people with certain types of PAH who are stable on their current treatment.
Seattle, WashingtonAges 18 years+ - NCT06350032RecruitingPhase 3
Testing treprostinil safety in children with PAH
This trial tests a medicine called treprostinil in children with severe pulmonary arterial hypertension (high blood pressure in the lungs). The study aims to see if it is safe and tolerable for kids who need this kind of therapy.
Vienna, State of ViennaAges Up to 18 years - NCT06968962Recruiting
Starting PAH treatment: one drug first or two drugs together?
This study compares starting with one medication versus two medications together for people with pulmonary arterial hypertension (PAH). It aims to find out which approach works better for low- or intermediate-risk patients.
Hangzhou, ZhejiangAges 18–80 - NCT06649110RecruitingPhase 1/Phase 2
A study of LTP001 for healthy people and those with PAH
This study tests an investigational medicine called LTP001 for pulmonary arterial hypertension (PAH). Part A checks safety in healthy volunteers, and Part B tests if it helps people with PAH by improving blood flow in the lungs.
Scottsdale, ArizonaAges 18–100 - NCT06549452Recruiting
Mobile health app to help teens with pulmonary hypertension exercise
This trial tests whether a smartphone app can help adolescents with pulmonary hypertension stay active and improve their health. If you are a teen with stable PH and can use an activity tracker, this study may be a good fit.
Nashville, TennesseeAges 10–21 - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Fresno, CaliforniaAges 18–75 - NCT05967299RecruitingPhase 1
IV ZMA001 study in healthy adults
This Phase 1 trial tests how an IV medicine called ZMA001 behaves in healthy people and checks for early safety. It may help future studies of the drug by confirming dosing and effects in people before testing in patients.
Bethesda, MarylandAges 18–60 - NCT05452889RecruitingEarly Phase 1
PET scan study in pulmonary hypertension related to scleroderma
This early study uses a PET scan (a type of imaging test) to better understand lung blood-vessel disease in people who have pulmonary hypertension related to scleroderma. It may help researchers find how imaging signals relate to disease and risk.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07617376RecruitingPhase 4
Flu shot before leaving hospital after heart problems
This study tests whether giving a flu vaccine to patients before they leave the hospital after a heart condition improves their health. The vaccine may help protect your heart and prevent serious flu complications while you recover.
WroclawAges 18 years+ - NCT05841615Recruiting
Atrial fibrillation and high blood pressure ablation plus kidney nerve treatment
This trial tests whether treating atrial fibrillation with a catheter procedure plus treating high blood pressure through kidney nerve treatment works better together. It may help control rhythm and blood pressure, but you must meet several heart, kidney-artery, and safety requirements.
Xiamen, FujianAges 18–75 - NCT06099015Recruiting
Cera vascular plug study for blocking blood vessels
This study tests a device called the Cera Vascular Plug System to block blood flow in certain arteries or veins. It may help patients who need this type of treatment for conditions like abnormal blood vessels or bleeding.
Bad HersfeldAges 18–85 - NCT06753786Recruiting
Blood thinner timing study for bleeding stroke patients
This study looks at when it is safest to start blood thinners to prevent blood clots (deep vein thrombosis) after a type of bleeding stroke called hypertensive intracerebral hemorrhage. Researchers want to find the best time to start this prevention treatment.
MoscowAges 18 years+ - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05952999Enrolling by invitation
Studying Hospital-At-Home care done from home
This trial looks at how well a “Hospital at Home” program works when people start from the emergency department or are already in the hospital and can be cared for at home. It may help teams improve care at home for certain medical conditions and situations.
Peoria, IllinoisAges 18 years+
Hear when a new Pulmonary Hypertension trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pulmonary hypertension?
- Yes. Clin2 currently lists 247 recruiting pulmonary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.