Clinical trials
Radiation clinical trials
Below are recruiting radiation clinical trials, each written for real people, not researchers. We’re tracking 1,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04838899Recruiting
Radiation for limited, progressing prostate cancer on abiraterone
This study tests whether a very focused type of radiation (SABR) can control a small number of prostate cancer spots that are starting to grow while you’re already on abiraterone. It may help by treating only the areas that are progressing, while other areas remain controlled.
Toronto, OntarioAges 18 years+ - NCT04682158RecruitingPhase 2
Propranolol added to standard chemoradiation for esophageal cancer
This trial studies whether adding propranolol (a common blood-pressure/heart medication) to standard chemotherapy and radiation can improve outcomes for people with esophageal adenocarcinoma. You would start propranolol around the time of treatment, with careful heart monitoring and study follow-up.
Buffalo, New YorkAges 18 years+ - NCT05412082RecruitingPhase 1
Smart chemo and radiation plan for locally advanced rectal cancer
This Phase 1 study tests a “smart” total treatment plan using chemotherapy (chemo) and radiation before surgery for people with locally advanced rectal cancer. The goal is to see if this approach is safe and can work well while helping plan treatment based on your situation.
Miami, FloridaAges 18 years+ - NCT05354570RecruitingPhase 2
Radiation for thymic cancer that has spread to lung lining
This Phase 2 study tests a precise type of chest radiation that targets cancer in the lung lining (pleura) while trying to protect healthy lungs and organs. It may help people with thymic cancer that has spread to the pleura, including cases that return after prior treatment.
Basking Ridge, New JerseyAges 18–79 - NCT04318717RecruitingPhase 2
Pembrolizumab plus radiation for resected mucosal melanoma
This trial studies whether giving pembrolizumab (an immunotherapy) together with a targeted form of radiation can help after surgery for mucosal melanoma. It aims to lower the chance of the cancer coming back and improve outcomes in people whose tumor was removed.
St Louis, MissouriAges 16 years+ - NCT04402788RecruitingPhase 2/Phase 3
Radiation added to immune therapy for extensive small cell lung cancer
This trial tests whether adding radiation therapy to standard immune therapy (atezolizumab) after initial chemo can help people with extensive-stage small cell lung cancer live longer and control the cancer better. You must have a good response (partial response) or stable disease after initial treatment, plus several lab/imaging checks to confirm safety.
Birmingham, AlabamaAges 18 years+ - NCT03546829RecruitingPhase 1
Testing targeted radiation plus short anti-microbial treatment
This early safety study tests a combination of focused radiation and a targeted anti-microbial (antibiotic/antifungal/antiviral/anti-parasite) plan for certain lung cancer that is starting to progress in a few spots. It aims to see whether this approach is safe and helps control the small areas of progressing cancer after prior treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02422550Recruiting
MRI imaging methods to improve radiation planning and response checks
This study tests MRI scanning and image analysis methods to help doctors plan radiation treatment more accurately and assess how well it’s working. You might help improve how MRI is used for radiation planning and follow-up.
Basking Ridge, New JerseyAges 18 years+ - NCT05301283RecruitingPhase 2
Adaptive radiation therapy before surgery for soft-tissue sarcoma
This trial tests a personalized (“adaptive”) radiation plan before surgery for high-grade soft-tissue sarcoma that can be removed. It may help shrink the tumor and improve how well surgery can treat the cancer.
Tampa, FloridaAges 18 years+ - NCT07150546RecruitingPhase 1
Radiation and Peptide Therapy for Large Gut Neuroendocrine Tumors
This trial combines external radiation with a targeted radioactive drug (PRRT) to treat large, slow-growing neuroendocrine tumors in the gut that have spread and are not removable by surgery. It aims to see if this combination works better than either treatment alone.
Atlanta, GeorgiaAges 18 years+ - NCT03516461Recruiting
Fecal transplant study for bowel injury after radiation
This study tests whether transferring stool bacteria (a fecal microbiota transplant) can improve “radiation enteritis,” a bowel problem that happens after radiation treatment. It may help restore gut bacteria and reduce symptoms after your radiation therapy.
Nanjing, JiangsuAges 18–85 - NCT06369610RecruitingPhase 2
Less hormone therapy with radiation for prostate cancer
This trial tests whether some men with high-risk prostate cancer can safely receive less hormone therapy when combined with radiation. It aims to reduce side effects while still effectively treating the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT01696721Recruiting
Pediatric radiation therapy registry for children under 22
This study is a registry that collects information from children and teens who receive radiation therapy at participating hospitals. It helps researchers learn how radiation is used in pediatrics and may improve future care.
Palo Alto, CaliforniaAges Up to 21 years - NCT07530172RecruitingPhase 2
Radioembolization vs. External Radiation for Liver Cancer
This study compares two ways of delivering targeted radiation to treat hepatocellular carcinoma (liver cancer): radioembolization, which uses tiny beads to deliver radiation directly through blood vessels, and external beam radiation therapy, which aims radiation from outside the body. The trial will help doctors understand which approach works better for patients with a limited number of tumors.
Detroit, MichiganAges 18 years+ - NCT06499870RecruitingPhase 2
Study of two drugs with radiation for high-risk prostate cancer
This trial tests whether combining two hormone therapy drugs, relugolix and enzalutamide, with radiation therapy can help treat very high-risk prostate cancer. The goal is to see if this combination is safe and effective for men whose cancer has a high chance of coming back.
Chicago, IllinoisAges 18 years+ - NCT06434350RecruitingPhase 1/Phase 2
Enfortumab vedotin and radiation for advanced bladder cancer
This trial tests a drug called enfortumab vedotin combined with radiation therapy for people with locally advanced bladder cancer that hasn't spread to distant organs. The goal is to see if this combination works better than radiation alone and helps control the cancer.
Houston, TexasAges 18 years+ - NCT05829291Recruiting
Alpha Radiation Seeds for Liver Cancer Spread Treatment
This trial tests a new treatment called DaRT (alpha radiation seeds) implanted directly into liver tumors that have spread from colorectal cancer. The seeds deliver targeted radiation to shrink tumors while reducing damage to healthy liver tissue, as part of a two-stage surgical plan.
Montreal, QuebecAges 18 years+ - NCT06410443Recruiting
Steroid treatment for radiation-induced bowel injury
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
Shenyang, LiaoningAges 18 years+ - NCT06746428Recruiting
Activity coaching during pelvic radiation for endometrial cancer
This study tests whether coaching on physical activity can help women with endometrial cancer feel better during pelvic radiation therapy. You will use a website or app to track your activity and get support from a coach.
Alexandria, VirginiaAges 18 years+ - NCT06008730RecruitingPhase 2
Proton beam radiation after lung cancer surgery
This trial tests if proton beam radiation therapy is safe and effective after surgery for non-small cell lung cancer that has spread to lymph nodes in the chest. It is for people who have already had chemotherapy before their surgery.
Atlanta, GeorgiaAges 18 years+ - NCT06453486RecruitingPhase 2
High dose radiation for pancreatic cancer after chemo
This trial tests whether giving a strong, focused dose of radiation can help people with locally advanced pancreatic cancer that has shrunk or stayed stable with first-line chemotherapy. It aims to improve outcomes for those who cannot have surgery.
Toronto, OntarioAges 18 years+ - NCT07476209Recruiting
Salivary gland procedure vs light therapy for dry mouth from radiation
This trial compares two treatments—a salivary gland procedure (sialendoscopy) and a light therapy (photobiomodulation)—to prevent dry mouth caused by radiation therapy for head and neck cancer. If you are about to start radiation and meet the dose limits, you may be eligible.
AlexandriaAges 18 years+ - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT07121335Recruiting
SABR for limited metastatic cancer
This trial tests a precise, high-dose radiation treatment (SABR) for people whose cancer has spread to a few spots (up to 5) and is not growing in the brain or been previously treated with radiation in those same spots.
SeoulAges 18 years+
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Common questions
- Are there clinical trials for radiation?
- Yes. Clin2 currently lists 1,052 recruiting radiation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.