Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,324 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04944914RecruitingPhase 3
Camrelizumab with targeted radiation for limited nasopharyngeal cancer spread
This trial tests whether combining camrelizumab (an immune medicine) with stereotactic body radiotherapy (high-precision radiation) works better than camrelizumab alone. It’s for people whose nasopharyngeal cancer has spread to a small number of spots in the body and may help control those metastases longer.
Guangzhou, GuangdongAges 18–70 - NCT04952480RecruitingPhase 2
Adaptive chest radiation for newly diagnosed small cell lung cancer
This study tests a customized (“adaptive”) way to give radiation to the chest for newly diagnosed small cell lung cancer. It aims to improve how well treatment targets the tumor while safely adjusting to tumor changes during therapy.
Edmonton, AlbertaAges 18 years+ - NCT04986293Recruiting
CPAP or BiPAP to reduce motion during radiation
This study tests whether using a breathing machine (CPAP or BiPAP) can help keep you still during radiation treatment. This may improve how accurately radiation is delivered for certain cancers treated with curative intent.
Groningen, Provincie GroningenAges 18 years+ - NCT04989647RecruitingPhase 3
Stage IB1 to IIA cervical cancer surgery with possible radiation
This Phase 3 trial studies how best to treat intermediate-risk cervical cancer using radical surgery, with or without additional radiation after surgery. It may help find which approach lowers the chance the cancer comes back for patients with certain tumor risk features.
PragueAges 18–85 - NCT05037461Recruiting
MR-guided radiation for pancreas tumors in MEN1 patients
This study tests a precise, MRI-guided radiation plan for certain small pancreas neuroendocrine tumors in people with MEN1. It may help control tumor growth when surgery is needed or when remaining small tumor spots are left after prior surgery.
UtrechtAges 18 years+ - NCT05102747Recruiting
Surgery-like brain radiation for up to 5 metastases
This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).
BordeauxAges 18 years+ - NCT05124236Recruiting
Pre-surgery vs post-surgery focused radiation for brain metastases
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
InnsbruckAges 18 years+ - NCT05142982Recruiting
Radiation or watchful waiting after chemo for seminoma
This study compares giving radiation versus observation (no immediate radiation) for men with advanced seminoma whose PET-CT scan shows a leftover mass after first-line chemotherapy. It aims to see which approach controls the disease better while protecting quality of life.
Mumbai, MaharashtraAges 18–80 - NCT05165056Recruiting
Light therapy to prevent vaginal side effects from radiation
This study tests whether photobiomodulation (a light-based therapy) can help prevent and lessen vaginal problems caused by radiation for endometrial cancer. If you get radiation to the pelvis, the trial aims to improve comfort and reduce tightening or damage over time.
Genk, LimburgAges 18 years+ - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05216900Recruiting
Breast reconstruction with radiation given before surgery
This study looks at how breast reconstruction works when radiation is planned around the time of surgery, including in some people before surgery depending on lymph node results. It may help improve safety and outcomes for people needing mastectomy and chest/radiation therapy.
Bilthoven, UtrechtAges 18–75 - NCT05328505Recruiting
Imaging-guided radiation for prostate cancer that came back
This trial tests whether a special scan (PSMA PET) can help doctors aim and adjust radiation more precisely when prostate cancer returns after surgery. It may help by increasing dose to areas that look involved while lowering dose to uninvolved pelvic areas.
London, OntarioAges 18 years+ - NCT05334459Recruiting
Radiation and medicines after surgery for new metastatic breast cancer
This trial looks at giving radiation and anti-cancer medicines after surgery to treat newly diagnosed (de novo) metastatic breast cancer. It may help patients by improving local control of the breast area while also treating cancer throughout the body.
AnkaraAges 18–80 - NCT05343325RecruitingPhase 2
Neoadjuvant low-dose radiation with chemo-immunotherapy for head and neck cancer
This Phase 2 study tests whether giving low-dose radiation before surgery—along with chemotherapy and an immunotherapy drug—can work better and be safe for treating locally advanced head and neck squamous cell cancer. It may help shrink tumors before surgery and reduce the chance of the cancer coming back.
Zhuhai, GuangdongAges 18–70 - NCT05352321Recruiting
Surgery plus targeted chemoradiation versus standard chemoradiation
This trial compares two treatment plans for newly diagnosed, operable nasopharyngeal cancer: adding surgery plus targeted chemoradiation versus standard chemoradiation alone. It aims to see whether the surgery-based plan improves control of the cancer and related outcomes.
Guangzhou, GuangdongAges 18–70 - NCT05354596Recruiting
SBRT radiation trial for central lung tumors
This trial studies a focused, high-dose radiation treatment called SBRT for lung tumors that are hard to operate on, including very central tumors near major airways or organs. It may help people control tumor growth while limiting radiation exposure to nearby critical structures.
AalborgAges 18 years+ - NCT05370144Recruiting
Pre-surgery chemotherapy and radiation for esophagus cancer
This study tests a new pre-surgery treatment plan that combines chemotherapy with focused, shorter-course radiation for esophagus or stomach-where-it-meets-the-esophagus (GEJ) adenocarcinoma. The goal is to shrink the tumor before surgery and improve treatment outcomes.
Calgary, AlbertaAges 18–80 - NCT05397262Recruiting
Bladder cancer treatment with radiation plus heat therapy
This trial studies adding “heat treatment” (hyperthermia) to standard bladder cancer care using radiation, sometimes with chemotherapy. It may help the radiation work better, but your eligibility depends on cancer stage, your general health, and certain heart and metal-safety issues.
ErlangenAges 18 years+ - NCT05406167Recruiting
Tracking quality of life during radiotherapy with a new system
This study collects information about how you feel and how treatment is delivered while you receive radiotherapy using the RefleXion Medical radiotherapy system. It may help doctors improve care and better understand what affects quality of life during treatment.
Duarte, CaliforniaAges Any age - NCT05413473RecruitingPhase 1/Phase 2
Testing image-guided radiotherapy using MRI scans
This trial studies a way of planning and delivering radiation using MRI pictures to help target tumors more accurately. It may benefit people by improving how radiation is aligned, and it’s being tested for safety and effectiveness compared with the usual CT-based planning.
Edmonton, AlbertaAges 18 years+ - NCT05416164Recruiting
Testes less radiation after a complete response to medicines
This study checks whether some people with breast cancer who have no remaining cancer after medicine (neoadjuvant systemic therapy) can safely receive less radiation. It may help reduce side effects while still keeping cancer controlled.
Amsterdam, North HollandAges 18 years+ - NCT05431764RecruitingPhase 2
PD-1 treatment plus radiation for limited metastatic nasopharyngeal cancer
This Phase 2 trial tests adding a PD-1 “immunotherapy” medicine (a type of cancer-fighting antibody) along with stereotactic body radiotherapy (very focused radiation) to treat nasopharyngeal cancer that has spread to only a few places. It may help shrink remaining visible spots after initial local radiation and see whether this “consolidation” approach improves control of the cancer.
Guangzhou, GuangdongAges 18–70 - NCT05439031RecruitingPhase 2
Stereotactic radiation to reduce recurrent dangerous heart rhythm episodes
This Phase 2 study tests a precise form of radiation therapy to control recurrent ventricular tachycardia (VT), a dangerous fast heart rhythm. It may help people whose VT keeps coming back despite heart medicines and/or ablation, especially when ablation is not possible.
Amsterdam, North HollandAges 18 years+ - NCT05438836Recruiting
Adaptive radiation planning for anal cancer treatment
This trial tests an online, adaptive way to plan and adjust radiation during treatment for people with biopsy-proven anal cancer. The goal is to better target the cancer while keeping side effects as low as possible.
HerlevAges 18 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,324 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.