Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,309 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07072351RecruitingPhase 1/Phase 2
Radiation plus chemoimmunotherapy for gastroesophageal junction cancer
This trial tests a shorter course of radiation combined with chemotherapy and immunotherapy to shrink gastroesophageal junction cancer before surgery. It aims to make the tumor removable and improve outcomes.
Xiamen, FujianAges 18 years+ - NCT07005570RecruitingPhase 2
Short radiation and chemo with or without immunotherapy for rectal cancer
This trial tests if adding an immunotherapy drug (PD-1 inhibitor) and a targeted therapy (bevacizumab) to short-course radiation followed by chemo can improve outcomes for patients with locally advanced rectal cancer that is pMMR/MSS. The goal is to shrink the tumor before surgery and possibly avoid the need for more extensive treatment.
Guangzhou, GuangdongAges 18–75 - NCT07448077RecruitingPhase 2
Short radiation with immunotherapy for rectal cancer
This trial tests a combination of short-course radiation, chemotherapy, and an immunotherapy drug (Enlonstobart) for patients with a specific type of rectal cancer called pMMR. It aims to see if this approach can shrink tumors before surgery and improve outcomes.
Shijiazhuang, HebeiAges 18 years+ - NCT05912075RecruitingPhase 1
New pre-surgery radiation plus ASTX660 for rectal cancer
This early-phase trial tests adding ASTX660 (a new drug) to pre-surgery radiation for locally advanced rectal cancer. It aims to improve control of the tumor before surgery, making it more likely that the surgeon can remove it with clear margins.
Lyon, RhöneAges 18 years+ - NCT06595108Recruiting
Targeted therapy and radiation for advanced liver cancer
This trial tests a combination of immunotherapy (atezolizumab), targeted therapy (bevacizumab), and targeted radiation for advanced liver cancer that cannot be surgically removed. The goal is to see if this approach helps control the cancer.
Yongin-siAges 19–80 - NCT07339774RecruitingPhase 2
Traditional Chinese medicine for mouth sores from radiation
This trial tests whether a traditional Chinese medicine can help prevent or reduce the severity of mouth sores caused by radiation therapy for head and neck cancer. If you are scheduled to get radiation for non-spreading head or neck cancer, this treatment might help protect your mouth.
Chengdu, SichuanAges 18–65 - NCT07726407Recruiting
Surface-guided radiation for head and neck cancer
This trial tests a special camera system (SGRT) to help you stay still during head and neck radiation. It may make treatment more accurate and comfortable by using your own breathing to guide positioning.
Guangzhou, GuangdongAges 18–75 - NCT03742687Recruiting
Testing a shorter, stronger radiation schedule for lung cancer
This trial studies a different way to deliver radiation to people with locally advanced, non-operable non-small cell lung cancer. It may help by aiming to treat the tumor effectively with a different radiation timing and dose pattern.
AarhusAges 18 years+ - NCT04025164Recruiting
Shorter vs standard breast radiation after lumpectomy
This study compares a shorter course of radiation to a standard longer course after breast-conserving surgery (lumpectomy). It’s meant to see which schedule works just as well while focusing on safety and cancer control.
Guiyang, GuizhouAges 18–70 - NCT04083937Recruiting
Radiation after prostate surgery for men with prostate cancer
This study looks at different radiation approaches after prostate surgery to see which strategy works best. You may be able to join if your cancer is at a stage where radiation to the prostate bed is planned, and you have not had prior radiation.
HeidelbergAges 18 years+ - NCT04115267Recruiting
Registry study tracking side effects from radiation and medicines
This study follows people with cancer to better understand which treatments cause certain side effects when radiation is combined with targeted (molecular) medicines. Your participation may help doctors predict and manage side effects more safely in the future.
Montreal, QuebecAges 18 years+ - NCT04299646RecruitingPhase 2
Stereotactic radiation for limited spread in kidney cancer
This trial tests whether targeted, high-precision radiation (stereotactic radiotherapy) can control a small number of growing kidney cancer metastases while you continue systemic treatment. It may help people who have “oligoprogressive” disease, where only 1–3 spots are getting worse.
AlbiAges 18 years+ - NCT04506008RecruitingPhase 2
Radiation followed by surgery for soft tissue sarcoma
This trial tests a treatment plan where you first get a shorter (hypofractionated) course of radiation and then have surgery to remove the tumor. It may help control the cancer locally in certain soft tissue sarcomas and improve surgical outcomes.
Nashville, TennesseeAges 18 years+ - NCT04513444RecruitingPhase 2
Medical hypnosis to reduce anxiety during cancer radiotherapy
This Phase 2 study tests whether medical hypnosis can help people feel less anxious while they receive radiation treatment for cancer. It targets adults who have moderate to very high anxiety right after treatment planning.
ToulouseAges 18 years+ - NCT04583254RecruitingPhase 2
Shorter radiation plan for certain early cervical cancers
This trial tests a feasibility (“can it be done safely?”) approach that delivers radiation in a shorter schedule for some cervical cancer patients. It also uses weekly cisplatin chemotherapy and includes a radiation procedure called brachytherapy to improve treatment effectiveness.
Kelowna, British ColumbiaAges 18 years+ - NCT04636008RecruitingPhase 1/Phase 2
Immunotherapy with radiation for MSI-H or dMMR rectal cancer
This trial tests the drug sintilimab combined with a specific radiation schedule to treat rectal cancer that is MSI-H or dMMR (tumor DNA repair/instability markers). It may help shrink the tumor and improve outcomes when standard options are limited or not yet started.
Chengdu, SichuanAges 18 years+ - NCT05055648RecruitingPhase 3
Proton vs photon radiation for esophageal cancer before surgery
This trial compares proton therapy and standard photon therapy given before surgery for esophageal (or stomach–esophagus) cancer. It aims to see which radiation approach works better and is safer as part of a combined treatment plan.
LeuvenAges 18 years+ - NCT05059379RecruitingPhase 3
Different radiation fields after breast cancer surgery
This trial compares two ways of giving radiation to lymph node areas near the collarbone after surgery for invasive breast cancer. It aims to see which radiation approach works better and is safer for preventing cancer returning in these lymph nodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05192876Recruiting
Review of outcomes and side effects during radiation treatment
This study collects information about results and side effects from people receiving radiation therapy at a specific hospital. It may help improve how radiation treatment is planned and monitored in the future.
Winterthur, Canton of ZurichAges 16–105 - NCT05248633RecruitingPhase 2
Chemo plus radiation versus radiation alone for one plasmacytoma
This Phase 2 study compares giving chemotherapy with radiation versus radiation alone for people with a single plasmacytoma (a localized plasma-cell tumor). It aims to see whether adding chemotherapy improves control of the disease while keeping side effects acceptable.
BeijingAges 18–80 - NCT05439278RecruitingPhase 3
Radiation schedules plus temozolomide for elderly glioblastoma
This study compares a standard radiation schedule versus a shorter, higher-dose radiation schedule, both with the chemotherapy medicine temozolomide, in older adults with newly diagnosed glioblastoma. It aims to see which approach works better and is practical for people age 70 and older.
SeoulAges 70 years+ - NCT05512286Recruiting
Radiation experience after breast surgery with belly flap
This trial looks at how people feel (patient-reported outcomes) and how safe treatment is when radiotherapy is given after a mastectomy with a DIEP belly skin-flap reconstruction. It may help doctors understand which experiences to expect and how to improve care.
Nanning, GuangxiAges 18 years+ - NCT05514327Recruiting
Radiation plus CAR-T for relapsed lymphoma after chemo
This study tests an “ultra-fraction” radiation treatment given before CAR-T therapy to help control aggressive lymphoma that has come back or did not respond. It may help some people bridge (bridge = hold the disease stable) while they wait for CAR-T to work.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05554276RecruitingPhase 2
PD-1 immunotherapy, chemotherapy, and radiation for advanced cervical cancer
This trial tests whether chemotherapy plus an immune treatment called PD-1, along with radiation, can help people with cervical cancer that cannot be removed with surgery. It’s aimed at locally advanced, unresectable cervical squamous cell cancer.
ShanghaiAges 18–70
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,309 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.