Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,321 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03858205Recruiting
Low-dose radiation to relieve pain from bone tumors
This trial studies whether low-dose radiation can reduce pain from a specific bone lesion caused by multiple myeloma. It may help people whose main problem is painful bone metastasis, with targeted treatment to the painful spot.
Duarte, CaliforniaAges 18 years+ - NCT03856372Recruiting
Shorter radiation schedule after mastectomy for high-risk breast cancer
This trial compares a shorter radiation plan to a standard longer plan after mastectomy for people considered high risk. It may help reduce treatment time while still trying to prevent breast-cancer recurrence.
Suzhou, JiangsuAges 18–75 - NCT03909282Recruiting
Surgery now versus radiation then delayed surgery for DCIS
This trial compares two approaches for ductal carcinoma in situ (DCIS): having surgery first versus getting radiation first and then having surgery later. It aims to see which plan controls DCIS better while affecting treatment timing and outcomes.
Stanford, CaliforniaAges 18 years+ - NCT03914378Recruiting
Study how radiation and cisplatin affect hearing in head and neck cancer
This study looks at how radiotherapy, and possibly cisplatin chemotherapy, affect hearing in people treated for head and neck cancer. It may help doctors better predict hearing side effects and plan hearing monitoring or prevention.
ManchesterAges 18 years+ - NCT03920033Recruiting
Radiation schedule for prostate cancer PSA relapse after surgery
This trial compares two different radiation schedules to treat prostate cancer that returned based on rising PSA blood tests after prostatectomy (prostate removal). If you qualify, it may help you and your team choose a radiation approach with the goal of controlling PSA relapse.
SeoulAges 20 years+ - NCT03948100Recruiting
Yoga coaching for lung or esophageal cancer during radiation
This study tests whether a guided yoga program helps people with lung or esophageal cancer improve strength, daily functioning, and quality of life while they receive radiation therapy. It also involves a family caregiver, to support the patient during treatment.
Houston, TexasAges 18 years+ - NCT03978377Recruiting
Checks heart and lung effects after chest radiation
This study looks at how chest radiation treatment affects the heart and lungs in people with certain lung or esophagus cancers. It may help doctors better predict and prevent these side effects during curative (aimed at cure) radiotherapy.
LeuvenAges 18 years+ - NCT03978039Recruiting
Sarcoma patient registry for people treated in France
This trial builds a national database of people diagnosed with sarcoma in French cancer centers. It may help researchers better understand sarcoma types and care patterns, which can improve future treatment decisions.
BordeauxAges Any age - NCT03997643RecruitingPhase 2
Radiation plan trial to help protect swallowing after mouth cancer
This Phase 2 study tests whether changing the “radiation volume” (how much area is treated) can better preserve swallowing after surgery for oral cavity squamous cell cancer. It may help reduce swallowing problems while still treating the cancer safely.
Miami, FloridaAges 18 years+ - NCT07703033Recruiting
Heart Impact Study for Breast Cancer Radiotherapy
This study looks at how information about the heart may affect treatment decisions for people receiving radiation therapy for breast cancer. It aims to help reduce heart-related side effects from treatment.
CopenhagenAges 35 years+ - NCT06686771RecruitingPhase 3
Radiation for limited growth in advanced lung cancer on immunotherapy
This trial tests whether giving high-precision radiation to a few spots that are growing during immunotherapy (with or without chemotherapy) can help people with advanced lung cancer. It aims to see if treating these limited areas of resistance can extend the time the cancer stays under control.
Phoenix, ArizonaAges 18 years+ - NCT04035642Recruiting
Single high-dose MRI-guided radiation for intermediate prostate cancer
This trial tests whether a single, image-guided radiation treatment can treat intermediate-risk prostate cancer while better protecting the urethra (the urine tube). It may help patients get effective cancer control with potentially fewer urinary side effects, depending on the results.
LisbonAges 18 years+ - NCT04060706Recruiting
Testing new computer tools for radiation treatment planning
This study tests how well new computer methods (called algorithms and machine learning) can support radiation therapy decisions. You might benefit by helping improve how radiation is planned and checked, especially for cancers treated with curative-intent therapy.
Cambridge, CambridgeshireAges 18 years+ - NCT04085029Recruiting
Study registry for patients getting focused radiation for spread disease
This study keeps a registry (a record) of people with metastatic (spread) cancer who are receiving focused, high-dose radiation to body sites outside the brain. It aims to better understand outcomes and care patterns for these patients.
Cary, North CarolinaAges 18 years+ - NCT04094454Recruiting
Vaginal dilation during pelvic radiation for anal cancer
This trial studies a method to make vaginal dilation easier during pelvic radiotherapy in women with anal cancer. It may help reduce or prevent treatment-related vaginal narrowing and improve comfort and function.
HeidelbergAges 18 years+ - NCT04100174RecruitingPhase 2
HDR radiation boost for prostate cancer during standard treatment
This study tests adding a targeted “boost” of HDR (high-dose-rate) internal radiation to the prostate along with standard external beam radiation. It may help improve cancer control while keeping the treatment focused on the area seen on scans and biopsy.
Montreal, QuebecAges Any age - NCT04104529Recruiting
Registry study for adults getting metabolic radiotherapy
This trial collects health and lab information from adults treated with metabolic radiotherapy in the nuclear medicine department. It may help doctors better understand how these treatments work for thyroid cancer, neuroendocrine tumors, or prostate cancer.
Bordeaux, AquitaineAges 18 years+ - NCT04109755RecruitingPhase 2
Pembrolizumab plus radiation before surgery for rectal cancer
This trial tests whether giving pembrolizumab (an immunotherapy medicine) together with short-course radiation before surgery helps people with localized rectal cancer. It is mainly for tumors that are microsatellite stable (MSS).
GenevaAges 18 years+ - NCT04158843Recruiting
Local surgery vs comfort treatment for limited breast cancer spread
This trial compares a more direct local treatment (targeting a small, limited spot) versus a comfort-focused palliative approach for breast cancer that has spread only to one side of the upper arm bone or breastbone area. It aims to see which approach works better while keeping side effects manageable.
Hangzhou, ZhejiangAges 18–75 - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT04170946RecruitingPhase 1
Talazoparib plus chest radiation after extensive small-cell lung cancer
This Phase 1 trial tests whether the medicine talazopib, given along with chest radiation, can better control extensive-stage small-cell lung cancer after initial chemotherapy. It is for people whose cancer has not worsened after finishing standard chemotherapy.
Toronto, OntarioAges 18 years+ - NCT04188535Recruiting
MRI scans during radiation treatment
This study does repeated MRI (detailed brain/body imaging) while you receive radiation therapy. It aims to see how these serial scans relate to treatment and outcomes, which could help improve care planning for different cancers.
Boston, MassachusettsAges 18 years+ - NCT04210492RecruitingPhase 1/Phase 2
Radiation for centrally located lung cancer, tested in 3 treatments
This trial tests a safer, lower-dose radiation approach given in three sessions for centrally located lung tumors. It aims to deliver effective treatment while protecting nearby sensitive structures like the heart, esophagus, and major airways.
Greenwich, ConnecticutAges 18 years+ - NCT04220749RecruitingPhase 2
Radiation vs mouth surgery for HPV-negative throat cancer
This Phase 2 trial compares two standard cancer treatments—radiation or surgery through the mouth—for HPV-negative oropharyngeal throat cancer. It aims to find out which approach works better while keeping side effects and quality of life acceptable.
London, OntarioAges 18 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,321 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.