Clinical trials
Randomized Controlled Trial clinical trials
Below are recruiting randomized controlled trial clinical trials, each written for real people, not researchers. We’re tracking 627 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06941675Recruiting
Automated insulin system for LADA diabetes
This trial tests a hybrid closed-loop insulin pump system for people with LADA (a slow-progressing form of autoimmune diabetes). It aims to see if the system can improve blood sugar control and reduce hypoglycemia.
Taiyuan, ShanxiAges 18–70 - NCT06947928RecruitingPhase 2/Phase 3
Vaccine plus immunotherapy for Merkel cell cancer
This trial tests an experimental vaccine (IFx-Hu2.0) followed by the immunotherapy drug pembrolizumab in people with advanced Merkel cell carcinoma who have not been treated with checkpoint inhibitors before. The goal is to see if this combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07269457RecruitingPhase 2
Vitamin D3 for recovery after mild to moderate brain injury
This trial tests if taking vitamin D3 can help reduce swelling and speed up recovery after a mild to moderate traumatic brain injury. It is for people who have low vitamin D levels.
LagosAges 18–65 - NCT07285226Recruiting
Creatine for muscle loss in older adults
This trial tests whether taking creatine HCl can help older adults with muscle loss (sarcopenia) improve muscle strength. If you are over 60 and have weak grip strength, this study might be for you.
BelgradeAges 60 years+ - NCT07489937Recruiting
Arm exercise effects on the shoulder tendon
This study compares how two different arm exercises affect the shoulder tendon (supraspinatus) in people with and without shoulder pain. It may help find better ways to exercise without causing injury.
Gainesville, FloridaAges 18–45 - NCT07604909RecruitingPhase 2
Serplulimab plus chemotherapy for early-relapsed colorectal cancer
This trial tests a new immunotherapy drug called serplulimab combined with standard chemotherapy or targeted therapy for colorectal cancer that has come back within a year after surgery. The goal is to see if adding this immune-boosting drug helps control the cancer better than chemotherapy alone.
ShanghaiAges 18 years+ - NCT07642661RecruitingPhase 2
Folinic Acid for Autism in Young Children
This study tests whether folinic acid (a B-vitamin supplement) can help improve autism symptoms in children ages 3–6. Folinic acid may support brain function, and researchers want to see if it works better than placebo (a dummy pill).
Jerusalem, N/A = Not ApplicableAges 3–6 - NCT07647094RecruitingEarly Phase 1
Chemotherapy plus immunotherapy for advanced squamous lung cancer
This trial tests a combination of three drugs—two chemotherapy medications (carboplatin and nab-paclitaxel) plus an immunotherapy drug (serplulimab)—as a first-line treatment for advanced squamous cell non-small cell lung cancer. The goal is to see if this combination works better than standard treatment and is safe for patients who haven't received prior systemic cancer treatment.
Quzhou, ZhejiangAges 18–75 - NCT07619924Enrolling by invitationEarly Phase 1
Phage Cocktail for Hard-to-Treat Skin Infections
This study tests a new treatment called a phage cocktail (viruses that kill bacteria) for skin infections caused by bacteria that don't respond well to regular antibiotics. The treatment is applied directly to the wound to see if it's safe and effective.
Xi'an, ShaanxiAges 18–75 - NCT06028412Enrolling by invitation
Lobectomy vs. Sublobar Resection for Small NSCLC
This trial compares two types of lung surgery for early-stage non-small cell lung cancer. You may qualify if you have a small tumor (2 cm or less) with specific features on a CT scan. The goal is to see which surgery offers better outcomes.
Xi'an, ShannxiAges 18–75 - NCT06221709Recruiting
Radiofrequency for hip arthritis pain: a clinical trial
This trial tests whether a treatment called continuous radiofrequency can reduce pain from hip arthritis. It is for people with moderate arthritis in one hip who have had pain for more than six months.
Brasília, Federal DistrictAges 18 years+ - NCT07498127Enrolling by invitationPhase 2
Probiotics for colds in young children
This trial tests whether taking probiotics can help young children recover faster from common colds. If your child has a mild or moderate cold and is not taking other probiotics, they may be able to join.
Xuhui, Shanghai MunicipalityAges 3 months–6 years - NCT07098169Recruiting
Testing a program to improve self-awareness for schizophrenia
This trial tests a program called iTEST that helps people with schizophrenia or schizoaffective disorder improve how accurately they understand their own thoughts. The program combines device use with feedback from a clinician or loved one to support better self-awareness.
San Diego, CaliforniaAges 18–65 - NCT04480203Recruiting
Digital coping tools after new breast cancer diagnosis
This trial tests two online programs designed to help people cope after being diagnosed with breast cancer. It may help you manage stress and emotions during treatment or recovery.
OsloAges 20–69 - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT07081997RecruitingPhase 3
Higher-dose palopegteriparatide for hypoparathyroidism
This trial is for adults with hypoparathyroidism who are already taking a drug called palopegteriparatide (TransCon PTH) at a certain dose. It tests whether higher doses of this drug can better control calcium levels and reduce the need for other supplements.
Reno, NevadaAges 18 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT05996328Recruiting
Meal delivery study for older veterans with heart failure
This study tests if providing ready-to-eat meals to older veterans recently hospitalized with heart failure can help them recover and avoid going back to the hospital. It aims to make it easier to follow a heart-healthy diet at home.
Birmingham, AlabamaAges 60 years+ - NCT06407271Recruiting
Implant crown shape and gum health study
This study tests whether the shape of the implant crown (the part above the gum) affects the health of the gum and bone around a single front tooth implant. It's for people with a missing upper front tooth, healthy gums, and thick gum tissue.
Budapest, Pest CountyAges 18 years+ - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85 - NCT06561087RecruitingPhase 2
Nivolumab injection for high-risk mouth lesions
This trial tests whether injecting nivolumab directly into high-risk pre-cancerous mouth spots can prevent them from becoming cancer. You randomly receive either the drug or a placebo, and the study monitors how the spots change over time.
Houston, TexasAges 18 years+ - NCT06484374Recruiting
AI-robot guided surgery for large basal ganglia bleeding
This trial tests a new, less invasive brain surgery using a robotic arm guided by artificial intelligence (AI) to remove a large blood clot caused by a hemorrhagic stroke in the basal ganglia. It may be an option for people who can have surgery soon after the stroke and were previously independent.
NanjingAges 18 years+ - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT05765175Recruiting
Radioablation versus repeat ablation for hard-to-treat VT
This trial compares a heart procedure using targeted radiation (called radioablation) to a repeat catheter ablation for people with high-risk, hard-to-control ventricular tachycardia (VT). It aims to find which approach is safer and works better after standard ablation and amiodarone have not stopped the abnormal rhythm.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for randomized controlled trial?
- Yes. Clin2 currently lists 627 recruiting randomized controlled trial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized controlled trial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized controlled trial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.