Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,384 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05911230Recruiting
MRI test to tell tumor return from temporary treatment effects
This study uses an advanced MRI scan to help doctors tell the difference between true tumor regrowth and “pseudoprogression,” which is a temporary treatment-related change that can look like progression. If it works, it may guide the safest next steps, including whether surgery is helpful.
BaselAges 18 years+ - NCT06801730RecruitingPhase 2
Irinotecan liposomes plus bevacizumab for recurrent glioma
This trial tests a combination of two medications—irinotecan liposomes (a chemotherapy drug wrapped in fat particles) and bevacizumab (a drug that cuts off blood supply to tumors)—for people whose glioma (a type of brain tumor) has come back or worsened after initial treatment. The goal is to see if this combination can help control the tumor.
Lishui, ZhejiangAges 18–75 - NCT06800768Recruiting
PET scan for finding thyroid cancer that has returned after surgery
This trial tests a special PET scan (68Ga-FAPI) to see if it can better find thyroid cancer that has come back or spread after surgery. It may help your doctor decide on the best next steps for your care.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07448727Recruiting
Early PET scan for head and neck cancer on immunotherapy
This trial uses a special PET/CT scan early in treatment to see if first-line immunotherapy is working for people with recurrent or metastatic head and neck cancer. It aims to learn if early response can predict outcomes and help guide care.
Rome, ItalyAges 18 years+ - NCT07447076RecruitingPhase 2
New treatments for recurrent ATRT brain tumor
This trial tests new treatments for children and young adults whose ATRT brain tumor has come back or grown. It aims to find if these therapies can help control the tumor.
San Francisco, CaliforniaAges 1–39 - NCT07447687RecruitingPhase 1/Phase 2
Soy tomato juice for pancreatitis symptoms
This trial tests whether drinking a special soy tomato juice can help people with chronic or recurrent pancreatitis feel better and have fewer flare-ups.
Columbus, OhioAges 18–80 - NCT07444814RecruitingPhase 1
HWK-007 for advanced solid tumors
This trial tests a new drug called HWK-007, which is designed to target and attack cancer cells while sparing healthy ones. It is for people with specific advanced solid tumors (lung, endometrial, or ovarian cancer) that have not responded well to standard treatments.
Little Rock, ArkansasAges 18 years+ - NCT07441499Recruiting
Detecting bladder cancer recurrence with a blood test
This study uses a blood test to find and monitor urothelial cancer (a type of bladder cancer) and to watch for signs it may come back. It may help patients and doctors make better decisions about follow-up care.
TianjinAges 18 years+ - NCT07439913Enrolling by invitation
Predicting cancer return and bladder control after robot prostate surgery
This study looks at factors that can predict whether prostate cancer will come back in the 10 years after robot-assisted prostate removal surgery, and how well bladder control (urinary continence) recovers. It helps doctors understand which patients might do better long-term.
Banská BystricaAges Any age - NCT07443774Recruiting
Sticking with hormone and CDK4/6 therapy after breast cancer surgery
This study is looking at how well people stick to a treatment plan that combines hormone therapy with a pill called a CDK4/6 inhibitor after surgery for early-stage breast cancer. The goal is to learn more about adherence so doctors can help patients stay on track.
GrenobleAges 18 years+ - NCT07443579Recruiting
Mammogram order study for breast cancer survivors
This trial tests if changing the order of mammogram views makes the exam more comfortable for women who have had breast cancer surgery and radiation. You may be able to join if you are due for your first check-up mammogram after finishing treatment.
Beaumont, DublinAges 18 years+ - NCT07444619RecruitingPhase 1
Combination drugs for returning soft tissue sarcoma in young people
This trial tests if combining four drugs (pazopanib, trabectedin, ipilimumab, and nivolumab) can help treat soft tissue sarcomas that have come back. It is for children and young adults up to age 30.
Houston, TexasAges 1–30 - NCT07428616RecruitingPhase 2
Study of Zanzalintinib for recurring meningioma
This trial tests a drug called Zanzalintinib for people with meningioma that has come back or grown despite past treatments. It aims to see if the drug can stop or slow tumor growth.
Birmingham, AlabamaAges 18 years+ - NCT06812039RecruitingPhase 2
Perioperative treatment for high-risk liver cancer using HAIC, donafenib, and sintilimab
This trial tests a combination of treatments—chemotherapy delivered through the liver artery (HAIC), a targeted drug (donafenib), and an immunotherapy (sintilimab)—given before and after surgery for liver cancer that has a high chance of coming back. The goal is to see if this approach can lower the risk of recurrence.
Fuzhou, FujianAges 18–75 - NCT06202118Recruiting
Alpha radiation therapy for breast cancer in older or frail patients
This trial tests a new type of radiation therapy (DaRT) that uses tiny, implantable seeds to deliver targeted alpha radiation to breast tumors. It is designed for older patients (65+) or those who are too frail for surgery, offering a less invasive option for controlling the cancer.
JerusalemAges 65–120 - NCT06751134RecruitingPhase 1
Engineered immune cells for relapsed neuroblastoma in children
This trial tests a new type of immune cell therapy (called CNK-UT) for children whose neuroblastoma has come back or hasn't responded to standard treatments. The goal is to see if these cells can find and attack the cancer. Participation may be an option if your child's tumor has a specific marker (B7-H3) and their overall health is stable enough.
Nanjing, JiangsuAges 1–12 - NCT05596630Recruiting
Stereotactic radiation for small liver cancer recurrence safety
This trial tests a precise type of radiation to treat small liver cancer that has come back after prior treatment. It aims to help with safety and long-term outcomes while protecting nearby organs and healthy liver.
Hangzhou, ZhejiangAges 18–80 - NCT04903899RecruitingPhase 2
Lutetium-DOTATATE for relapsed or hard-to-treat neuroblastoma in children
This Phase 2 trial tests a targeted radioactive medicine called 177Lutetium-DOTATATE in children with high-risk neuroblastoma that has returned or did not respond to treatment. It’s designed for tumors that show strong uptake on special scans, which may help the medicine find and treat cancer cells.
Copenhagen, CopenhagenAges 1.5 years+ - NCT07417397RecruitingPhase 3
TACE after surgery for high-risk liver cancer
This trial tests whether a liver-directed treatment called TACE (transarterial chemoembolization) after surgery can help prevent liver cancer from coming back in people with high-risk features.
NanningAges 18–70 - NCT07424092RecruitingPhase 2
Virus injection for children with recurrent brain tumors
This trial is testing a virus called DNX-2401, which is injected directly into the tumor, for children and young adults with high-grade brain tumors that have come back or are hard to treat. The goal is to see if this virus can shrink or control the tumor.
UtrechtAges 1–25 - NCT07424560Recruiting
Bladder Cancer DNA Testing Study
This study looks for specific DNA changes in bladder cancer tumors using a precise test. It aims to better understand the disease and may help guide future treatment choices.
Lanzhou, GansuAges 18 years+ - NCT07420959RecruitingPhase 1/Phase 2
ABBV-383 for Waldenström macroglobulinemia that came back
This trial tests a new drug called ABBV-383 for people with Waldenström macroglobulinemia that has returned or stopped responding to treatment. The drug is given as an infusion and aims to attack the cancer cells. This might help if you've already tried a BTK inhibitor.
Rochester, MinnesotaAges 18 years+ - NCT07418593RecruitingPhase 4
Blood test for pancreas function in chronic pancreatitis
This trial tests a new blood test to measure how well your pancreas works. It may help people with chronic pancreatitis understand their condition and quality of life.
Baltimore, MarylandAges 18 years+ - NCT07419464RecruitingPhase 2
Testing 5-FU for head and neck cancer that has returned
This trial tests the drug 5-fluorouracil (5-FU) in people with head and neck cancer that has come back or spread. It aims to see if 5-FU can help when other treatments have stopped working.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,384 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.