Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,424 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07498478RecruitingPhase 2
Tinengotinib and fulvestrant for advanced HR+ HER2- breast cancer
This trial tests a new drug called tinengotinib combined with the hormone therapy fulvestrant for people with HR-positive, HER2-negative breast cancer that has come back or spread. It is for those who have already tried a CDK4/6 inhibitor and at least one hormone therapy.
Guangzhou, GuangdongAges 18 years+ - NCT07500116Recruiting
Home monitoring after minor stroke or TIA
This study tests whether using a wearable and smartphone app at home can help monitor recovery after a minor stroke or mini-stroke (TIA) – possibly reducing hospital stays while keeping you safe. If you have mild symptoms that stabilized in the ER, and you have help at home, you may qualify.
BarcelonaAges Any age - NCT07500701RecruitingPhase 3
Comparing two radiation schedules for rising PSA after prostate surgery
This trial is testing two types of radiation therapy for men whose PSA level rises after prostate removal, but without clear signs of cancer spread on a PSMA PET scan. The goal is to see which radiation schedule works better to control the cancer.
Seoul, Gangnam-guAges 20 years+ - NCT07501650RecruitingPhase 1
Pembrolizumab plus ultrasound bubbles for head and neck cancer
This trial combines the immunotherapy drug pembrolizumab (Keytruda) with a special ultrasound technique that uses tiny bubbles to make the treatment work better. It is for people with HPV-negative head and neck cancer that has come back or spread to other parts of the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07506239Recruiting
Laser therapy for low-grade brain tumors in young people
This trial tests a laser treatment called LITT for low-grade glioma (a type of brain tumor) that has come back or is growing despite prior treatment. It aims to see if the laser is safe and effective in young people aged 2 to 25.
San Francisco, CaliforniaAges 2–25 - NCT07508618RecruitingPhase 4
Qidong Yixin Granule for preventing atrial fibrillation after ablation
This trial tests whether a traditional Chinese medicine granule, Qidong Yixin, can help prevent atrial fibrillation from coming back after a heart ablation procedure. It is for people with persistent atrial fibrillation who have not had good results from other heart rhythm medications.
HangzhouAges 18–80 - NCT07512232Recruiting
Rectal Lavage During Surgery to Lower Cancer Recurrence Risk
This trial tests whether rinsing the rectum with special fluid during minimally invasive surgery for mid-to-low rectal cancer helps prevent the cancer from coming back locally. The procedure aims to wash away cancer cells that might have leaked into the surgical area.
Guangzhou, GuangdongAges 18–75 - NCT07521137RecruitingPhase 2
Biweekly occidiofungin for recurring yeast infections
This study tests occidiofungin, a new antifungal medication inserted into the vagina twice a week to prevent recurring yeast infections (vulvovaginal candidiasis). The goal is to see if this treatment can stop yeast infections from coming back.
Birmingham, AlabamaAges 18–65 - NCT07540260Recruiting
Imaging-Guided Radiation Therapy for Advanced Kidney Cancer
This trial uses two types of PET scans to better target radiation therapy in patients with advanced clear cell kidney cancer that has spread or returned. The goal is to combine radiation with standard drug treatments to improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07542080Recruiting
Comparing Two Surgical Approaches for Recurring Bladder Leakage
This pilot study compares two different surgical techniques to treat stress urinary incontinence (leaking urine when you cough, sneeze, or exercise). Researchers want to see which approach works better for women whose leakage has returned after previous treatment.
LondonAges 18–100 - NCT07546383Recruiting
New Immunotherapy Combination for Advanced Head and Neck Cancer
This trial tests a new combination of two immunotherapy drugs (called iparomlimab and tuvonralimab), with or without chemotherapy, for head and neck squamous cell carcinoma that has returned or spread after previous treatment. The goal is to see if this combination can help people with this cancer live longer with fewer side effects.
Haikou, HainanAges 18–75 - NCT07560865RecruitingPhase 1
New Cell Therapy for Recurring Brain Cancer
This study tests FT536, a new cell-based treatment, for people with a specific type of brain cancer (WHO Grade 4 astrocytoma) that has come back after standard treatment. The trial combines the new therapy with surgery to see if it can help stop the cancer from growing further.
Minneapolis, MinnesotaAges 18–75 - NCT07566585RecruitingPhase 1
Safety study of BSB-2002 for relapsed or refractory AML with NPM1 mutation
This is a Phase 1 trial testing a new drug called BSB-2002 in patients with acute myeloid leukemia (AML) that has come back or stopped responding to previous treatments. The drug is designed specifically for patients whose cancer cells have a particular genetic change (NPM1 mutation) and may help control the cancer by activating the immune system.
St Louis, MissouriAges 18 years+ - NCT07573839Recruiting
Predicting bipolar disorder relapse using voice and video analysis
This study uses artificial intelligence to analyze speech patterns and facial expressions from people with bipolar disorder to predict who might have a relapse. If successful, it could help doctors identify warning signs earlier and prevent episodes before they happen.
ShanghaiAges 18–64 - NCT07581821RecruitingPhase 2
Immunotherapy plus targeted drugs for advanced nasopharyngeal cancer
This trial tests a combination of three drugs (sintilimab, anlotinib, and chemotherapy) for nasopharyngeal cancer that has returned or spread after initial treatment. The goal is to see if this combination helps slow or shrink the cancer.
Zhuhai, GuangdongAges 18–65 - NCT07589413Recruiting
Blood markers and fluid absorption during bladder cancer surgery
This study looks at how fluid absorbed during bladder cancer removal surgery affects cell-free DNA (tiny pieces of cancer DNA) in your blood. Researchers want to understand if these blood markers can help predict surgery outcomes and guide treatment decisions.
Lanzhou, GansuAges 18 years+ - NCT07589543RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Advanced Ovarian Cancer
This trial tests a new type of immune cell therapy (CAR-NK cells) designed to target and fight ovarian cancer that has returned or stopped responding to standard treatments. The therapy uses cells from your own body that have been modified in the lab to recognize and attack cancer cells.
Shenzhen, GuangdongAges 18–75 - NCT07594964RecruitingPhase 1
Safety Study of XH001 Injection for High-Risk Recurrent Solid Tumors
This early-stage trial tests a new injection called XH001 as an additional treatment after surgery for patients with high-risk cancers that have come back. The goal is to check if it's safe and whether it helps prevent the cancer from returning again.
BeijingAges 18–70 - NCT07601763Recruiting
Pulsed Field Ablation for Atrial Fibrillation Treatment
This trial tests a newer ablation technique called pulsed field ablation to treat atrial fibrillation, a heart rhythm disorder. The goal is to see if this method works well and is safe for patients who need treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07611136Recruiting
Brain Vessel Disease Progression After Different Stroke Types
This study examines how small blood vessel disease in the brain progresses differently depending on whether you've had a recent stroke. Researchers will use MRI scans to track changes over time and better understand this condition.
Ulm, Baden-WurttembergAges 18 years+ - NCT07611656Recruiting
Surgery to Fix Septate Uterus Before IVF Treatment
This study tests whether a minimally invasive surgery to remove a uterine septum (a wall dividing the uterus) improves pregnancy success rates in IVF. You would have the procedure before starting IVF treatment if your uterus has this condition and you've had difficulty getting pregnant.
Changsha, HunanAges 20–40 - NCT07611838Recruiting
Predicting ABPA Recurrence Using Blood and Immune Markers
This study helps doctors predict whether allergic bronchopulmonary aspergillosis (ABPA)—a serious lung condition caused by fungal allergy—will come back after treatment. Researchers will analyze blood samples and immune system markers to identify patients at higher risk of relapse, which could improve how doctors monitor and treat you.
Jinan, ShandongAges 18–80 - NCT07616986Recruiting
Laser heat treatment for early-returning brain cancer
This trial tests a minimally invasive laser procedure (LITT) to treat glioblastoma that comes back very soon after initial treatment. The goal is to see if laser heat can destroy the tumor before standard radiation and chemotherapy begin, potentially improving outcomes.
BernAges 18 years+ - NCT07625423RecruitingPhase 1
Gene therapy injection for advanced head and neck cancer
This trial tests a new treatment where a specially designed virus carrying an anti-cancer gene is injected directly into tumors in the head and neck area. It's for patients whose cancer has come back or spread after prior chemotherapy and who cannot have surgery or radiation.
Chengdu, ChinaAges 18–65
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,424 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.