Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 502 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03261544Recruiting
Compare hip abductor repair methods after hip bone replacement
This trial studies which surgical method best reconnects the hip “abductor” muscle after a proximal femur (upper thigh bone) replacement. It may help improve walking and recovery by guiding surgeons toward the most effective repair technique.
Durham, North CarolinaAges 16–75 - NCT07514650Recruiting
Citrate Blood Thinner Safety in Critical Kidney Care
This study tests whether a specific blood-thinning method using citrate works safely and effectively in critically ill patients whose kidneys have suddenly stopped working and need a special filtering machine. Researchers want to confirm that this approach prevents dangerous blood clots while keeping patients safe.
Barcelona, BarcelonaAges 18 years+ - NCT07516145Recruiting
Robotic catheter repair for leaky tricuspid heart valve
This trial tests a new robotic catheter procedure to repair a leaky tricuspid valve (the valve on the right side of your heart). Instead of open-heart surgery, doctors thread a tiny device through a vein in your neck to fix the valve. It may be an option if you have severe leaking and your heart team thinks surgery is too risky for you.
ShatinAges 18–90 - NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05202977Enrolling by invitation
TAVR valve replacement for older adults with aortic valve narrowing
This trial tests a newer transcatheter (catheter-based) aortic valve replacement device to improve symptoms and safety in older adults with severe aortic stenosis. You may qualify if you’re too high-risk for open-heart surgery and the valve/artery measurements fit the device.
Hefei, AnhuiAges 65 years+ - NCT07532785Recruiting
Water and Land Exercise Before Knee Replacement Surgery
This trial tests whether a 6-week program combining weekly water-based exercise and three times weekly land-based training can help reduce knee pain and improve strength before total knee replacement surgery. The program aims to help you recover better after your operation.
London, EnglandAges 18 years+ - NCT06578936Recruiting
Massage and warmth after knee replacement
This study tests whether gentle belly massage and a warm pack help people have a bowel movement more quickly after total knee replacement surgery done under spinal anesthesia. It looks at how these simple, drug-free treatments may help get your bowels working again after surgery.
AdanaAges 18 years+ - NCT03650010Recruiting
Study of ankle replacement outcomes over many years
This study looks at how well total ankle replacement surgery works and what the scans show over time. It mainly includes adults who had the surgery in a specific date range, to better understand results after ankle replacement.
Milan, MilanoAges 18 years+ - NCT06888908Recruiting
Blood volume changes during hip replacement surgery
This trial measures how blood volume and fluids shift in the body during and after hip replacement surgery. It helps doctors better understand fluid management for patients having this procedure.
CopenhagenAges 18 years+ - NCT06880497Recruiting
Comparing knee sounds after two types of knee replacement
This study compares how much noise the knee makes (and how it feels to the patient) after two different kinds of total knee replacement surgery. It aims to help patients know what to expect after surgery.
AuxerreAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06768762Recruiting
Home activity program for knee replacement recovery
This study tests a home-based physical activity program for adults who have had a knee replacement at least a year ago. It aims to help you become more active with remote support and coaching.
Columbia, South CarolinaAges 18 years+ - NCT06091397Recruiting
Italian ankle replacement survey study
This study tests a new Italian questionnaire for people who have had total ankle replacement surgery. It helps doctors understand how well patients forget about their new ankle in daily life.
BolognaAges 25–80 - NCT05642260Recruiting
Fall-prevention program after knee replacement for older women
This trial tests whether a structured fall-prevention program can reduce the number of falls in older women after total knee replacement surgery. It may help you stay safer as you recover and move around.
Kuwait CityAges 60 years+ - NCT05660525Recruiting
Helping rural smokers quit with pharmacist support and nicotine replacement
This study tests a smoking-cessation program delivered through community pharmacies in rural Appalachia. It may help people quit smoking using nicotine replacement (patch or lozenges) plus support from pharmacists.
Charlottesville, VirginiaAges 18 years+ - NCT04604509RecruitingPhase 4
Smoking quit plan using counseling and nicotine-free medicines
This trial tests whether a quit program that combines counseling with medicines (nicotine replacement, varenicline, or bupropion) helps people stop or cut down smoking. It’s also delivered through telehealth, with repeated check-ins to see how well the plan works and whether it’s safe for you.
Houston, TexasAges 18 years+ - NCT03636464Recruiting
Antibiotic testing in people on kidney dialysis
This trial studies how common antibiotics move through the body when someone is on kidney replacement therapy (dialysis), including when dialysis starts during treatment. The results may help doctors choose the right antibiotic dose and timing for better infection treatment.
Abu DhabiAges 18 years+ - NCT06447922Enrolling by invitation
Metal Levels After Knee Replacement
This study measures metal levels in the blood after knee replacement surgery. It may help researchers understand how metal from the new joint affects the body.
Rochester, MinnesotaAges 18–100 - NCT06875154Enrolling by invitation
How original tricuspid valve disease affects new valve lifespan
This study looks at how the type of tricuspid valve problem you had originally (narrowing, leaking, or both) might affect how long a replacement valve lasts. If you have had only tricuspid valve replacement surgery, this trial could help doctors understand your long-term outcome better.
MaastrichtAges 18 years+ - NCT02803294RecruitingPhase 4
Study of heart valve replacement outcomes in Chinese patients
This study records results of a minimally invasive procedure to replace a narrowed or leaking heart valve. It may help doctors understand how well the treatment works and what complications happen in Chinese patients.
Hanzhou, ZhejiangAges 18 years+ - NCT07601269RecruitingEarly Phase 1
New Mitral Valve Implant for Heart Valve Disease
This early-stage trial tests a new device called the ReValve System that replaces a damaged mitral valve (the valve that controls blood flow in your heart). The study is for people with a weakened heart who have leaking mitral valves and are experiencing heart failure symptoms.
São Paulo, São PauloAges 18 years+ - NCT06285162Recruiting
Nerve health monitor during ICU dialysis
This trial uses a special monitor (called ANI) to check how well your nervous system is working while you are on continuous kidney dialysis in the ICU. It may help doctors better understand your body's response to fluid removal.
BronAges 18 years+ - NCT07431762RecruitingPhase 4
Aspirin vs. Warfarin after bioprosthetic valve surgery
This trial compares aspirin to warfarin in the first six months after receiving a bioprosthetic (tissue) heart valve. It aims to find which treatment better prevents blood clots without causing excessive bleeding.
OsakaAges 19 years+
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 502 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.