Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05710809Recruiting
Exercise and health check study for older colorectal cancer patients
This trial looks at sarcopenia (loss of muscle strength/size) and vertigo (feeling dizzy or off-balance) in older adults with colorectal cancer. It tests whether a structured, exercise-based approach can help these issues alongside cancer care.
CopenhagenAges 65 years+ - NCT06278909Recruiting
Nerve stimulation for stubborn anxiety
This study tests a new, non-invasive treatment using mild electrical stimulation on a nerve in your face (trigeminal nerve) to help with anxiety that hasn't improved with other treatments. It aims to see if this approach is safe and helpful for people with generalized anxiety disorder who have not responded to standard medications.
Kingston, OntarioAges 18–65 - NCT07218809RecruitingPhase 3
Comparison of AZD5335 vs standard treatments for advanced ovarian cancer
This trial tests a new drug, AZD5335, against standard treatments (mirvetuximab soravtansine or chemotherapy) for women with platinum-resistant ovarian cancer. It aims to see if AZD5335 works better based on the level of a protein called FRα on your tumor cells.
Birmingham, AlabamaAges 18 years+ - NCT07213804RecruitingPhase 3
Study of sofetabart mipitecan for ovarian cancer
This trial tests a new drug called sofetabart mipitecan for people with ovarian cancer that has come back after treatment. It is for those whose cancer is either resistant to platinum chemo (Part A) or sensitive to it (Parts B and C). The study will see if the drug can help shrink or slow the cancer.
Birmingham, AlabamaAges 18 years+ - NCT07217301RecruitingPhase 3
Comparing TAK-928 to docetaxel for advanced lung cancer
This study tests a new drug called TAK-928 against the standard chemo docetaxel for people with advanced squamous non-small cell lung cancer. You may be able to join if you have already tried a checkpoint inhibitor and platinum chemotherapy, and your cancer has grown.
Jonesboro, ArkansasAges 18 years+ - NCT06829459RecruitingPhase 3
New drug combo vs chemo for resistant lung cancer
This trial tests a combination of two targeted drugs (Glumetinib and Osimertinib) against standard chemotherapy for people with non-small cell lung cancer that has stopped responding to initial targeted therapy. It may be an option if your tumor has a specific genetic change called MET amplification or overexpression.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07221279Recruiting
Walking study for weight and heart health in adults
This study tests if a specific number of daily steps can help overweight or obese adults improve body composition and reduce heart disease risk. It's for people who are otherwise healthy but may have high blood pressure or joint pain managed by medication.
Kennesaw, GeorgiaAges 20 years+ - NCT07221370RecruitingPhase 2/Phase 3
Vancomycin to prevent C. diff infection in ICU patients
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Moreno Valley, CaliforniaAges 18 years+ - NCT07218159Enrolling by invitation
Can a program help prevent partner violence?
This study looks at whether a program called IDEA3 can help prevent intimate partner violence. It is for college women who are already in the main IDEA3 study and have finished the 12-month survey.
Orlando, FloridaAges 17–26 - NCT07214441Enrolling by invitation
BE+ program for lung cancer survivors
This trial tests a program called BE+ for people who have finished treatment for non-small cell lung cancer. It aims to see if the program is practical and helpful for improving health after treatment.
Columbia, South CarolinaAges 21 years+ - NCT03903835RecruitingPhase 3
Biomarker-guided treatment for metastatic prostate cancer
This Phase 3 trial tests a prostate cancer treatment plan chosen using your tumor’s biomarker results. It aims to improve outcomes for men with metastatic prostate cancer starting first systemic treatment.
AalstAges 18 years+ - NCT05414292Recruiting
Testing rapamycin effect on exercise muscle function in older adults
This study looks at how rapamycin (a medication that affects a growth signal in the body) changes muscle responses when older adults do resistance exercise. It may help researchers understand whether this treatment could improve or alter muscle function with aging.
DerbyAges 50–90 - NCT05945524Recruiting
Study of how teclistamab works in multiple myeloma patients
This study looks closely at patients’ immune cells to understand why teclistamab helps in multiple myeloma. Your participation could help doctors better predict who benefits and how the treatment works.
Amiens, FranceAges 18 years+ - NCT07209761RecruitingPhase 3
New drug combo for drug-resistant TB (quabodepistat)
This study tests a new oral medication combination (quabodepistat with other drugs) for people with drug-resistant pulmonary TB. It aims to find a shorter, safer, and more effective treatment.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07207239Enrolling by invitation
Brain stimulation for treatment-resistant depression
This trial is testing a type of brain stimulation therapy called theta-burst rTMS to see if it helps with depression that hasn't improved with standard treatments. It also uses brain scans to predict who might respond best.
Budapest, Pest CountyAges 18 years+ - NCT07203378RecruitingPhase 2
Exercise program for energy and zest on Enhertu
This study tests whether a supervised exercise program can help reduce fatigue and improve energy for people with breast cancer who are taking the drug Enhertu. You would do both aerobic and resistance exercises over several weeks.
Salt Lake City, UtahAges 18 years+ - NCT06518915Recruiting
Baroloop trial for stubborn high blood pressure
This trial tests a device that helps control blood pressure by gently stimulating a nerve in your neck. It may help if your blood pressure stays high even while taking three different medications.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06931730Recruiting
Exercise and cognitive training for overweight individuals
This trial tests a program that combines exercise, cognitive training, and social activities to help people with overweight or obesity manage their energy balance. It may improve overall health and weight control.
Rome, ItalyAges 6–11 - NCT07199959Recruiting
Study on why entrectinib stops working in ROS1 lung cancer
This study looks at why the targeted drug entrectinib stops working in some people with ROS1-positive lung cancer. Participants will give blood or tumor samples before and after treatment to help researchers understand resistance.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07198724RecruitingPhase 1/Phase 2
A study of elacestrant plus Enhertu for advanced breast cancer
This trial tests a new combination of two targeted drugs (elacestrant and Enhertu) for people with a specific type of advanced breast cancer (HR-positive, HER2-low or ultra-low) that did not respond to standard treatments like CDK4/6 inhibitors. The goal is to see if this combination works better than current options.
Boston, MassachusettsAges 18 years+ - NCT07200830RecruitingPhase 3
Testing different schedules of a targeted radiation drug for advanced prostate cancer
This trial tests two different dosing schedules of a drug called Lutetium-177 PSMA RLT, which delivers radiation directly to prostate cancer cells. It is for men with advanced prostate cancer that has stopped responding to hormone therapy and has spread, who have not yet had chemotherapy for this stage of the disease.
Anchorage, AlaskaAges 18 years+ - NCT06621914Recruiting
Blood flow restriction training for military with leg injuries
This trial tests a low-weight exercise program using a special cuff on the leg (blood flow restriction) to see if it helps military personnel recover from leg injuries faster. It could be an option if pain is stopping you from doing normal rehab.
Loughborough, LeicestershireAges 18–55 - NCT06942559Recruiting
Brain stimulation for treatment-resistant OCD
This trial tests a new type of brain stimulation (TMS) that is timed to your brain's natural rhythms, targeting a part of the brain linked to OCD. It may help people whose OCD has not improved with standard treatments.
Toronto, OntarioAges 18–65 - NCT07192120RecruitingPhase 1/Phase 2
MHB048C for advanced solid tumors
This trial is testing a new medicine called MHB048C for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it can help shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,198 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.