Clinical trials
Rotator Cuff clinical trials
Below are recruiting rotator cuff clinical trials, each written for real people, not researchers. We’re tracking 142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT04864158Recruiting
Shoulder implant versus exercise program for damaged rotator cuff
This trial compares a shoulder implant (prosthesis) with an active exercise program for people whose rotator cuff has caused shoulder joint damage. The goal is to see which approach helps function and comfort better over time.
Aarhus NAges 60–85 - NCT03617562Recruiting
Compare two surgeries for large rotator cuff tears
This trial compares two different operations to treat large, hard-to-repair rotator cuff tears. If your tear is too damaged to be repaired in the usual way, the study tests whether one surgical approach may work better than a partial repair.
Toronto, OntarioAges 18–65 - NCT06257979Recruiting
Infection check during repeat rotator cuff surgery
This study looks for unexpected bacteria in the shoulder during repeat rotator cuff surgery. It aims to learn how often these hidden infections happen so doctors can better treat patients.
BeaumontAges 18 years+ - NCT07820592Enrolling by invitation
Pre-surgery exercises to speed recovery after rotator cuff repair
This study tests whether doing exercises before your shoulder surgery helps you recover faster and better after rotator cuff repair. If you are scheduled for arthroscopic shoulder surgery, this program might help you regain strength and movement more quickly.
TemucoAges 50 years+ - NCT07375277Recruiting
Biceps tendon transfer for large rotator cuff tears
This study tests a new surgical technique that uses your biceps tendon to help repair a large rotator cuff tear. It may be an option if you have not improved after at least 3 months of other treatments.
BalıkesirAges 18 years+ - NCT07239349Recruiting
Acne face wash to reduce shoulder surgery infection risk
This study tests whether using a special acne face wash before shoulder surgery can lower the risk of infection. If you have a rotator cuff tear and are scheduled for arthroscopic repair, you may be able to join.
TaipeiAges 18 years+ - NCT07154641Recruiting
Shoulder tendon transfer vs. reconstruction for large tears
This trial compares two surgeries to repair large rotator cuff tears (torn shoulder tendons). One moves a nearby tendon, the other uses a patch. It aims to find which works better for pain and mobility.
Athens, AtticaAges 18 years+ - NCT07076069RecruitingPhase 4
Rotator cuff repair pain study: fewer narcotics
This trial tests a mix of pain medicines (multimodal regimen) to see if it reduces the need for strong narcotics after arthroscopic rotator cuff repair. If you have a torn rotator cuff that hasn't healed with other treatments and you are scheduled for surgery, you may be able to join.
The Bronx, New YorkAges 18 years+ - NCT06868108Enrolling by invitation
Rotator cuff repair with flexible anchors: study of healing
This study follows people who had rotator cuff repair using a special stitching system with anchors (FSSA). It checks how well the tendon heals by looking at MRI scans taken about a year after surgery.
Charlotte, North CarolinaAges 18–70 - NCT06744218Recruiting
Remote rehab after rotator cuff surgery
This study tests if doing physical therapy at home via video calls works as well as going to a clinic after rotator cuff repair surgery. It may help you recover more conveniently.
Lagosanto, FerraraAges 40–70 - NCT06414005RecruitingPhase 2/Phase 3
TPX-115 injection for partial-thickness rotator cuff tear
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07658326Recruiting
Stress and rotator cuff surgery study
This study looks at how stress before surgery might affect recovery in people having rotator cuff surgery. You may be able to join if this is your first surgery for a torn rotator cuff and you don't have certain other health problems.
CornebarrieuAges 18 years+ - NCT06766630RecruitingPhase 2/Phase 3
Silk mesh for rotator cuff tear repair
This trial tests a new silk-based surgical mesh to help repair large rotator cuff tears. It's for people who have not gotten better with other treatments and need surgery.
Hangzhou, ZhejiangAges 50–75 - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT07219654RecruitingPhase 2
Study of TPX-115 for partial rotator cuff tear
This study tests an experimental treatment called TPX-115 for people with a partial-thickness rotator cuff tear. It aims to see if the treatment can reduce pain and improve function compared to standard care.
La Mesa, CaliforniaAges 18 years+ - NCT06969625Recruiting
Shoulder Block for Pain Relief After Rotator Cuff Surgery
This study tests a special numbing injection (shoulder block) to see how well it controls pain after arthroscopic rotator cuff repair. If you are having this type of shoulder surgery and are generally healthy, this trial may help you recover with less pain.
Zagazig, Al SharqiaAges 21–65 - NCT06971497Recruiting
ActivBraid implant for rotator cuff repair study
This study tests a special implant (ActivBraid) to help repair a torn rotator cuff. If you have a moderate-sized tear and haven't had prior shoulder surgery, you may be able to join.
Cleveland, OhioAges 18–75 - NCT06823206Recruiting
Movement training for shoulder pain from rotator cuff issues
This trial tests whether learning movement techniques combined with sensorimotor training (exercises that improve how your brain controls your shoulder) can help reduce chronic shoulder pain caused by rotator cuff problems. It may be a good fit if you have had shoulder pain for over three months with changes seen on MRI or ultrasound.
Hong KongAges 50 years+ - NCT05400798Enrolling by invitation
Study of injected regenerative cells for rotator cuff tears safety
This study checks the long-term safety of an injection made from your own fat cells for people with a chronic rotator cuff tear. It is mainly focused on monitoring side effects and outcomes over time.
Phoenix, ArizonaAges 30–75 - NCT07232511Recruiting
Cuff-assisted exercise for shoulder pain
This study tests whether using a blood pressure cuff during gentle shoulder exercises can help reduce pain and improve movement. It is for people with ongoing shoulder pain related to the rotator cuff (the muscles and tendons that help lift and rotate your arm).
Valencia, ValenciaAges 18–65 - NCT05896475Recruiting
Looking for who may develop shoulder pain from silent tears
This study looks at risk factors that predict when an “asymptomatic” (painless) rotator cuff tear might start causing symptoms. You may benefit by getting careful assessment and monitoring of your shoulder health over time.
Ghent, Oost-VlaanderenAges 55–100 - NCT07628244Recruiting
Anesthesia methods for rotator cuff shoulder surgery
This trial compares two different anesthesia maintenance approaches during arthroscopic (keyhole) rotator cuff repair surgery to see which one provides better visibility for the surgeon. You would receive general anesthesia combined with a nerve block in your shoulder.
Nice, Alpes-MaritimesAges 18 years+ - NCT07228936Recruiting
Pectoralis minor tightness and rotator cuff tears
This trial looks at whether tightness in a small chest muscle (pectoralis minor) is linked to rotator cuff tears. If you have a partial rotator cuff tear or a healthy shoulder, you might be able to join to help answer this question.
Ankara, CankayaAges 18–55
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Common questions
- Are there clinical trials for rotator cuff?
- Yes. Clin2 currently lists 142 recruiting rotator cuff studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.