Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 399 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05894265Recruiting
Test collagen patch versus standard care after rotator cuff repair
This study compares a collagen “patch” placed during arthroscopic rotator cuff surgery versus the usual standard repair. It looks at safety and whether the patch improves healing and shoulder function after surgery.
Houston, TexasAges 18–80 - NCT05913609Recruiting
Yaari Extractor safety test for difficult shoulder delivery
This trial studies whether the Yaari Extractor device is safe and effective when a baby’s shoulder gets stuck during vaginal birth. It may help doctors deliver the baby using additional steps when standard moves are not enough.
Miami, FloridaAges 18 years+ - NCT05981911Recruiting
Study of Xience Skypoint stents in everyday heart care
This trial is checking how well Xience Skypoint stents work and how safe they are for people who need them to open blocked heart arteries. It's for patients getting these stents as part of their normal treatment.
SeoulAges 19 years+ - NCT06008938Recruiting
Study tracking HEMGENIX for hemophilia B
This study watches how well HEMGENIX works and how safe it is for people with hemophilia B who are getting the treatment. It also compares data from adults on standard factor IX shots.
Rochester, New YorkAges 18 years+ - NCT06089616Recruiting
Long-term safety study of palovarotene in FOP patients
This study tracks the long-term safety and how well palovarotene works in people with FOP who are already taking it as part of their regular care. By joining, you help doctors learn more about the medicine over time.
San Francisco, CaliforniaAges 8 years+ - NCT06099730Recruiting
Pulsed field ablation for atrial fibrillation
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
Jonesboro, ArkansasAges 18–80 - NCT06100991Recruiting
Generalized Pustular Psoriasis Drug Safety Registry
This registry tracks the safety and effectiveness of GPP treatments in real-world settings. It helps doctors and researchers learn how well current and future medicines work for people with generalized pustular psoriasis.
Waltham, MassachusettsAges 18 years+ - NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06122285Recruiting
Bulevirtide for chronic hepatitis delta
This study tests a daily shot of Bulevirtide for people with long-term hepatitis delta and early-stage cirrhosis. It aims to see if the medicine is safe and works well.
Milan, MIAges 18 years+ - NCT06158750Recruiting
Flow diverter for brain aneurysms: safety and effectiveness study
This trial tests a device called a flow modulation device to treat certain brain aneurysms. It aims to see if the device is safe and works well for people with aneurysms that have not burst.
BeijingAges 18–80 - NCT06201598Recruiting
Treatment for brain aneurysms with flow-diverter stents
This study is testing if a type of stent called a flow-diverter is safe and effective for treating brain aneurysms. It may help patients who have an aneurysm that was found by chance, is causing symptoms, or has already ruptured.
A CoruñaAges 18 years+ - NCT06202027Recruiting
CRYSVITA safety and effectiveness in Korean patients
This study looks at the safety and effectiveness of CRYSVITA (burosumab) in real-world use among patients in South Korea. If you are already prescribed CRYSVITA for X-linked hypophosphatemia, your doctor may ask you to join this survey to help track how well it works and any side effects.
Wŏnju, Gangwon-doAges 1 day+ - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT06252935Recruiting
Collagen membrane for gum and bone repair
This trial tests a new collagen membrane (FormaAid®) for repairing gum and bone damage from gum disease. It may help people with deep gum pockets and bone loss who are not smokers and have well-controlled health conditions.
Taipei, TaiwanAges 18–70 - NCT06293378Recruiting
Sulfasalazine for liver fibrosis and cirrhosis
This study tests if sulfasalazine, a medicine already used for other conditions, is safe and helpful for people with liver scarring (fibrosis or cirrhosis). It is for patients with cirrhosis caused by certain liver diseases, like PBC, hepatitis B, hepatitis C, or alcohol use.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06313749Recruiting
Trial of a new surgery for glaucoma not helped by eye drops
This study tests a new minimally-invasive surgery called MIMS to lower eye pressure in people with open-angle glaucoma that isn't well controlled even with multiple eye drop medications. The surgery makes a tiny opening to help fluid drain and reduce pressure in the eye.
Dallas, TexasAges 40–85 - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Birmingham, AlabamaAges 18 years+ - NCT06312722Recruiting
Optilume BPH catheter system for enlarged prostate symptoms
This trial tests a device called Optilume BPH Catheter System for men with enlarged prostate that causes bothersome urinary symptoms. It aims to see how safe and effective it is in real-world use, offering a possible treatment for blocked urine flow without surgery.
Little Rock, ArkansasAges 50 years+ - NCT07694921Enrolling by invitation
Non-invasive brain stimulation for Alzheimer's disease
This trial tests if a safe, non-invasive electrical stimulation can help people with Alzheimer's disease. It aims to improve thinking and memory skills.
Hangzhou, ZhejiangAges 60 years+ - NCT07089576Recruiting
Study of the Arcevo LSA device for aortic arch repair
This trial tests a new device called Arcevo LSA to treat certain types of aortic arch problems, like dissections (tears) or aneurysms (bulges). It is for people who need open surgery, and the device helps fix the left subclavian artery area.
Birmingham, AlabamaAges 18–80 - NCT06328608RecruitingPhase 2/Phase 3
PRX-102 for children with Fabry disease
This study tests a new enzyme replacement therapy called PRX-102 for children with Fabry disease. It aims to see if the drug is safe and helps manage symptoms like pain and eye or skin changes.
Phoenix, ArizonaAges 2–17 - NCT06388720RecruitingPhase 2
Two chemotherapy drugs for bladder cancer after BCG
This study tests a combination of two chemotherapy drugs, mitomycin-C and gemcitabine, given directly into the bladder for people with high-risk bladder cancer that hasn't been controlled with BCG therapy. It's an option for those who can't or don't want to have their bladder removed.
Goyang-siAges 20 years+ - NCT06401772Recruiting
Body posture to prevent repeat brain bleed after surgery
This trial tests whether lying in a specific body position after surgery can help prevent a chronic subdural hematoma from coming back. It is for people aged 60 and older who have had a small drainage procedure for this type of brain bleed.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06408259RecruitingPhase 3
Comparing ozanimod and fingolimod for children with MS
This study compares two oral medications, ozanimod and fingolimod, to see which one works better and is safer for children and teenagers with relapsing-remitting MS. Both drugs help reduce MS attacks and slow down the disease.
Loma Linda, CaliforniaAges 10–17
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 399 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.