Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07116174Recruiting
Testing a new amniotic membrane dressing for diabetic foot ulcers
This study tests a new wound dressing made from amniotic membrane, called Xcell Amnio Matrix, to see if it helps heal diabetic foot ulcers that have not healed with standard treatments. If you qualify, you would receive the dressing along with regular wound care.
Fresno, CaliforniaAges 18 years+ - NCT07105579RecruitingPhase 2
Blinatumomab and donor cells after transplant for high-risk B-ALL
This trial tests whether giving two drugs—blinatumomab (an immunotherapy) and donor lymphocyte infusions (white blood cells from your donor)—can help prevent leukemia from coming back after a stem cell transplant for high-risk B-ALL. It is for people who are in remission with no sign of leukemia cells.
HangzhouAges 14–65 - NCT07104955Recruiting
Study on software to improve team meetings
This trial tests a new software tool designed to help medical teams work together more effectively and safely during multi-disciplinary meetings. If you are part of a medical team that holds these meetings, your participation could help improve how decisions are made.
LondonAges Any age - NCT05349955Recruiting
Primary care diabetes guideline program for older adults
This trial tests whether a diabetes treatment plan (based on published guidelines) delivered by primary care doctors in the community is safe and helpful for older adults. It focuses on people with type 2 diabetes who also have kidney problems and/or higher heart and blood-vessel risk.
Suzhou, JaingsuAges 65 years+ - NCT07093489Recruiting
LC16m8 mpox vaccine study in the DRC
This study tests whether a single dose of the LC16m8 mpox vaccine is safe and works in people living in the Democratic Republic of Congo. It also monitors for side effects and tracks mpox cases to see how well the vaccine protects the community.
KinshasaAges 1 year+ - NCT07083206Recruiting
Pitavastatin/ezetimibe for high cholesterol
This trial tests a combination pill of two cholesterol-lowering medicines (pitavastatin and ezetimibe) in adults who have been taking either atorvastatin or rosuvastatin for at least 3 months. It aims to see if switching to this new combination is safe and effective.
Yongin-siAges 19 years+ - NCT07078383Recruiting
Study of the Rapidlink device for aorta repair
This trial tests a device called Rapidlink that helps repair blood vessels branching off the aorta during open heart surgery. It may be an option if you need open surgery to fix your thoracic aorta.
Los Angeles, CaliforniaAges 18 years+ - NCT06977750Recruiting
Gelatin fluid for safe blood volume during surgery
This trial is testing a special fluid called succinylated gelatin (a type of colloid) given during surgery to help maintain blood volume. It is for people having planned surgery lasting less than 6 hours and who are in generally good health, without major heart, liver, or kidney problems.
Changsha, HunanAges 18–65 - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
Huntsville, AlabamaAges 18 years+ - NCT07062094Recruiting
Safety and Effectiveness of the Orbera365 Balloon for Weight Loss
This study tests a temporary balloon placed in your stomach to help with weight loss. The balloon stays in place for about a year and is removed at the end of the study. It is for people with a BMI between 30 and 50 who are looking for a non-surgical option.
PragueAges 18 years+ - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT07052396Recruiting
Dupilumab for COPD: long-term real-world study
This study looks at how well dupilumab works over time for people with COPD who still have symptoms despite standard treatments and who have a certain type of inflammation (elevated eosinophils). It uses data from regular doctor visits and patient questionnaires to understand real-world benefits and safety.
AuerbachAges 18 years+ - NCT07037537Recruiting
Nipple-sparing mastectomy with immediate reconstruction (fat and implant)
This trial tests a breast cancer surgery that removes the breast but saves the nipple, followed by immediate reconstruction with an implant and some of your own fat. It's for women with early-stage cancer that hasn't spread to lymph nodes.
Zhengzhou, HenanAges 18–70 - NCT07025304Recruiting
Study of REFLEX ULTRA 45 for nasal turbinate reduction in China
This trial tests a new device called REFLEX ULTRA 45 that uses radiofrequency energy to shrink the nasal turbinates (the fleshy shelves inside your nose) to help you breathe easier. It is for people with long-term nasal stuffiness who have not gotten relief from nasal sprays.
Guangzhou, GuangdongAges 18–65 - NCT07018544Enrolling by invitation
Wegovy safety and effectiveness study in Korea
This study watches how Wegovy (semaglutide) works and its side effects when given by doctors to patients with obesity or overweight in South Korea. It is not testing a new drug, but collecting information from routine care.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT07009847Recruiting
Study of the R21/Matrix-M malaria vaccine
This study looks at how well the R21/Matrix-M malaria vaccine works and how safe it is in children who received it. It compares children who got malaria (or died) to healthy children who also got the vaccine.
Bousse, Burkina FasoAges 5 months+ - NCT07001280Recruiting
Garadacimab for hereditary angioedema (HAE)
This study looks at how well a drug called garadacimab works and how safe it is for people with hereditary angioedema (HAE), a condition that causes sudden swelling. It tests the drug in people who are starting it for the first time as part of their regular care.
Phoenix, ArizonaAges 12 years+ - NCT05541341Recruiting
Tisagenlecleucel outcomes study in relapsed B-cell blood cancers
This study looks at how safe and effective tisagenlecleucel is for people in Brazil who have certain B-cell blood cancers that came back or did not respond to treatment. You may be included if you already received tisagenlecleucel outside a research study and can consent to share your medical data.
Minas Gerais, Belo HorizonteAges birth–100 years - NCT06973031Recruiting
Testing a new system for treating atrial fibrillation
This trial tests a new device that uses pulsed electric fields to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to see if this approach is safe and effective for people with AF that comes and goes or lasts for a short time.
KaiserslauternAges 18–80 - NCT06977126RecruitingPhase 1
Porphysome nanoparticles for imaging advanced gynecological cancers
This early-phase trial tests a new imaging agent called Porphysome nanoparticles to see if it can help doctors see gynecological cancers more clearly on scans. It's for women with advanced cancer that cannot be cured, and who are already receiving standard treatments like chemotherapy.
Toronto, OntarioAges 18 years+ - NCT06962800RecruitingPhase 3
Study of felzartamab for adults with primary membranous nephropathy
This study tests whether felzartamab, given as an infusion, can help treat primary membranous nephropathy (a kidney disease causing protein in the urine and swelling). It may reduce protein loss and improve kidney function compared to standard care alone.
Huntsville, AlabamaAges 18–80 - NCT06968741Recruiting
Study of a new artificial urinary sphincter for men with stress incontinence
This study tests a new device called UrOActive that helps men with stress urinary incontinence (leaking urine when coughing, sneezing, or moving). It aims to see if the device is safe and works well to control leaks.
Los Angeles, CaliforniaAges 22 years+ - NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
Jonesboro, ArkansasAges 18 years+ - NCT06931951Recruiting
Acupuncture with medicine for knee pain after a car accident
This trial tests a type of acupuncture that injects medicine into specific points (pharmacopuncture) to treat severe knee pain from a recent traffic accident. It looks at whether this treatment is safe and effective for people who are already in the hospital for their injury.
DaejeonAges 19–69
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.