Clinical trials
Seizures clinical trials
Below are recruiting seizures clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06922175Recruiting
Study on cenobamate and healthcare use in epilepsy
This study looks at how cenobamate (a medication for seizures) affects healthcare use, like hospital visits or emergency room trips, in people with epilepsy whose seizures were not well-controlled by 2 to 5 other medicines. It is a real-world study, meaning it uses medical records to understand the impact.
Freiburg im Breisgau, GermanyAges 18 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Birmingham, AlabamaAges 18–66 - NCT06866691RecruitingPhase 4
Seizure prevention after traumatic brain injury
This trial tests two medicines, levetiracetam and lacosamide, to see which works better at preventing seizures in people who have had a traumatic brain injury. The goal is to find the safest and most effective way to protect your brain after injury.
Winston-Salem, North CarolinaAges 18 years+ - NCT05874154Recruiting
Nerve surgery vs botox for spastic foot after stroke
This trial compares two treatments—tibial nerve selective surgery and botulinum toxin (botox) injections—to improve a stiff, turning-in foot after stroke. It aims to use goal-based care to see which option works better for walking and foot function.
BronAges 18–100 - NCT06736002Recruiting
Vitamin D for epilepsy: fewer seizures, less fatigue
This trial tests whether high doses of vitamin D can help reduce seizures and improve fatigue and quality of life in adults with refractory epilepsy who have not responded well to at least two medications.
TainanAges Any age - NCT06617845Recruiting
Optimizing brain stimulation for epilepsy
This study aims to find the best settings for brain stimulation devices already implanted in patients with epilepsy. It may help improve seizure control by adjusting how the device works.
Rochester, MinnesotaAges 6 years+ - NCT06388161Recruiting
Autoantibody study in new focal seizures
This research study looks for specific immune system markers (autoantibodies) in the blood and spinal fluid of people who have recently started having focal seizures (seizures that start in one part of the brain) with no known cause. Finding these markers could help doctors understand why the seizures started.
Hangzhou, ZhejiangAges 14–100 - NCT06549426Recruiting
Treating seizure activity after cardiac arrest
This trial tests a treatment for seizure-like brain activity that can happen after a cardiac arrest. It aims to see if treating these seizures quickly can improve recovery for people who are in a coma.
BrusselsAges 18 years+ - NCT06545643Recruiting
Sleep-sensitive seizure risk test with wearable EEG
This study uses a comfortable headband to track your sleep and brain activity. It may help better understand when seizures are likely to happen.
Durham, North CarolinaAges 18 years+ - NCT02824822Recruiting
Genetic test study for heart rhythm risk in people with seizures
This study checks whether genetic markers are linked to heart rhythm problems in people with epilepsy or seizure-related events, and in some close relatives. It may help doctors better spot who is at risk for dangerous heart rhythm issues.
Rochester, MinnesotaAges 18–50 - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT06466681Recruiting
Attention changes after a seizure in epilepsy
This study looks at how attention and concentration change right after a seizure in people with epilepsy. It uses a short hospital stay to track these changes, which may help improve understanding and future treatment.
LilleAges 18–80 - NCT06442748RecruitingPhase 3
Short vs long seizure medicine in brain tumor patients
This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.
Udupi, KarnatakaAges 18 years+ - NCT06401707RecruitingPhase 2
Seizure prevention after cardiac arrest
This study tests a seizure-prevention medicine called perampanel for people whose hearts stopped beating (cardiac arrest) and are now in the ICU. The goal is to see if it helps prevent seizures that can happen after such an event.
San Francisco, CaliforniaAges 18 years+ - NCT06362161Recruiting
New FND treatment program and care pathway
This study is creating a new team-based treatment program for people with functional neurological disorder (FND). It tests whether a coordinated care pathway helps patients get better results from therapy and psychiatry.
Birmingham, AlabamaAges 8–89 - NCT06108102Enrolling by invitation
Post-stroke epilepsy research database study
This trial is creating a global research database to learn more about seizures that happen after a stroke. By joining, you help doctors better understand who gets these seizures and how to treat them.
New Haven, ConnecticutAges 18 years+ - NCT03492060Recruiting
Study of genetic variants in neurogenetic disorders over time
This study looks at how people’s genetic test results relate to health changes over time in conditions caused by gene differences. If you already have genetic confirmation of a disease-causing variant, you may be able to join.
New York, New YorkAges Any age - NCT05944692Recruiting
Tripolar EEG test during seizure monitoring
This study checks whether a new type of EEG recording (a brain wave test) can detect seizure activity in people with epilepsy. You may join if you are already scheduled for routine and video EEG testing (and possibly inpatient monitoring) as part of your clinical care, including a brain MRI.
Phoenix, ArizonaAges 6 years+ - NCT05864547Recruiting
Study risk factors for seizures after a first stroke
This study looks at what factors can make seizures happen after a first stroke. It may help doctors identify who is more at risk so future care can be better targeted.
TrondheimAges 18–85 - NCT05784805Recruiting
Focused ultrasound treatment during EEG monitoring for ongoing seizures
This trial tests whether a focused ultrasound treatment can change brain electrical activity seen on an EEG in people with ongoing seizure emergencies. It may help doctors learn safer ways to modulate seizure activity when standard medicines are not fully stopping it.
New Haven, ConnecticutAges 19–85 - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Phoenix, ArizonaAges 12 years+ - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05374824Recruiting
Palliative surgery versus more seizure medicines for Lennox-Gastaut
This trial compares two treatment approaches for children with Lennox-Gastaut syndrome: palliative (comfort-focused) surgery versus adding more anti-seizure medicines. It aims to see which option works better for seizure control and day-to-day well-being.
Chicago, IllinoisAges Up to 26 years
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Common questions
- Are there clinical trials for seizures?
- Yes. Clin2 currently lists 104 recruiting seizures studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a seizures trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.