Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05725837RecruitingPhase 2
Paroxetine for circulation problems in early septic shock
This Phase 2 trial tests whether paroxetine can improve heart and blood-flow function in adults with septic shock that started within the last 48 hours. If you’re eligible, you may be asked to take the study medicine soon after diagnosis to see if it helps your cardiovascular function.
Colatina, Espírito SantoAges 18 years+ - NCT05770622RecruitingPhase 4
Vancocin dosing check in young infants with infections
This trial studies a better way to monitor and adjust vancomycin (an antibiotic) dosing in very young infants. It may help your baby get the right dose while reducing the risk of under- or over-dosing.
Melbourne, VictoriaAges birth–3 months - NCT05788861Recruiting
Study for children with severe strep skin or bloodstream infection
This trial is for people under 18 who have a confirmed invasive Group A strep infection, meaning strep bacteria found in places that are normally sterile (like the blood or deep tissues). It tests whether a specific study approach can help improve outcomes for children with these serious infections.
CréteilAges 1 day–17 years - NCT05793008Recruiting
Studying heart stress syndrome in sepsis using heart scans
This study looks at Takotsubo (also called stress cardiomyopathy) and heart problems caused by sepsis using specialized heart imaging (including PET). The goal is to better understand what triggers these conditions and how the heart is affected, which may improve diagnosis and care.
RomeAges 18 years+ - NCT05815628Recruiting
Testing next-generation sequencing in neutropenic sepsis
This trial studies whether advanced genetic testing (next-generation sequencing) can help doctors better understand and manage neutropenic sepsis—a serious infection risk when white blood cell counts are too low. You may be considered if you develop fever or sepsis quickly (within 24 hours) while your counts are low.
CologneAges 18 years+ - NCT05830669Recruiting
Remote preconditioning therapy for newly sick sepsis patients
This trial studies whether a “remote preconditioning” treatment given during early sepsis can help protect the kidneys and improve outcomes. It is for adults in the ICU very soon after sepsis begins.
MünsterAges 18 years+ - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT06058819Recruiting
New blood test to guide antibiotic use in newborns
This study is testing a new blood test to see if it can help doctors decide when to use antibiotics for newborns who may have a late-onset infection. The goal is to reduce unnecessary antibiotic use.
BronAges 1 week–2 weeks - NCT06072430RecruitingPhase 3
Testing a new fluid for septic shock with low blood pressure
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
Chandler, ArizonaAges 18 years+ - NCT06076200Recruiting
How Piperacillin/Tazobactam works in pregnant women and newborns
This study looks at how the antibiotic Piperacillin/Tazobactam moves through the body of pregnant women and their newborns. It may help doctors decide the best dose to prevent infections in babies at risk.
JinanAges 18 years+ - NCT06087315Recruiting
Study of oxygen use in children's hospitals
This study looks at how hospitals in six countries use pulse oximeters and oxygen therapy to treat children. It aims to find ways to improve oxygen delivery and care for children with serious illnesses.
Phnom PenhAges birth–15 years - NCT06100614Recruiting
Using a blood test to reduce antibiotics in preterm newborns
This study checks if a blood test (presepsin) can help doctors safely stop antibiotics earlier in preterm babies at moderate risk of infection. The goal is to reduce unnecessary antibiotic use.
Amsterdam, North HollandAges Any age - NCT06143137Recruiting
Long-term recovery after septic shock treatment
This study checks on people who had septic shock and were in the ReActIF-ICE trial. It looks at how their immune system recovered over time after an experimental therapy.
MagdeburgAges 18–80 - NCT06145841Recruiting
Gene test to guide infection treatment in AIDS
This study is for people with HIV/AIDS who develop severe pneumonia or septic shock. It uses a special genetic test (metagenomic next-generation sequencing) to find the exact germ causing the infection so doctors can choose the right antibiotic.
Guangzhou, GuangdongAges 18–65 - NCT06193980Recruiting
ICU recovery exercise test study
This trial looks at how well your heart and lungs work together after a long stay in the ICU on a breathing machine. It uses a simple exercise test to check your recovery after leaving the hospital.
Winnipeg, ManitobaAges 18 years+ - NCT06226441Recruiting
Aminoglycoside antibiotics for sepsis with low kidney function
This study tests how well aminoglycoside antibiotics work in people with sepsis who also have low kidney function. It may help find the best way to treat serious infections in patients with kidney problems.
Larissa, ThessalyAges 18 years+ - NCT06253325Recruiting
Early detection of patients at risk for sepsis
This trial is looking for patients who have an infection and are showing early signs of getting sicker, like a high warning score. It aims to find out if doctors can identify those at risk of sepsis sooner so they can start treatment earlier.
Southampton, HampshireAges 18 years+ - NCT06280872Recruiting
Cord clamping study for moderate and late preterm babies
This trial studies a different way of clamping the umbilical cord after birth to see if it helps moderately preterm babies (born between 32 and 37 weeks). It may improve their health right after delivery.
BrusselsAges 7 months–8 months - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06338124Recruiting
Lab tests to predict outcomes in sepsis patients
This study looks at whether certain blood test results can help predict how well people with sepsis will do. Sepsis is a serious infection that can affect the whole body. You may be able to join if you have sepsis and are over 18.
AsyutAges 18–70 - NCT06372444Recruiting
Kidney injury in severe infections study
This study looks at how severe infections like sepsis can hurt the kidneys. By using special scans (PET-CT), researchers hope to better understand why this happens, which could lead to better treatments.
UppsalaAges 30 years+ - NCT06380842Recruiting
Organ function after necrosectomy for pancreatitis with sepsis
This study looks at how a surgery to remove dead tissue from the pancreas (called open necrosectomy) affects organ function in patients with acute pancreatitis and sepsis. It may help doctors understand how to better treat this serious condition.
Chengdu, ChinaAges 18 years+
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 268 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.