Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06440304RecruitingPhase 4
Comparing treatments for ICU patients with resistant Acinetobacter infections
This trial compares different treatment options for patients in the ICU who have a resistant bacterial infection called Acinetobacter baumannii. If you have this infection after surgery, the study aims to find the best way to treat it.
ZagrebAges 18–90 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06464510RecruitingPhase 3
Treating sepsis with norepinephrine plus early vasopressin
This trial tests whether giving a second medicine called vasopressin early (along with norepinephrine) helps people with sepsis and low blood pressure better than waiting to use vasopressin only if norepinephrine doesn't work. It may improve blood pressure control and reduce the need for strong medicines.
Caxias do Sul, Rio Grande do SulAges 18 years+ - NCT06476171Recruiting
Blood test study for heart surgery patients
This study looks at blood test results from people having heart surgery with a heart-lung machine. It will help doctors understand and improve the use of these tests.
MoscowAges 18–80 - NCT06481410Recruiting
Methylene blue for severe septic shock
This trial is testing whether a medication called methylene blue can help people with severe septic shock who are already on strong blood pressure support (norepinephrine). The goal is to see if it improves survival and reduces the need for other treatments.
Hangzhou, ZhejiangAges Any age - NCT06499701Recruiting
Study of Fluid Resuscitation in Early Sepsis
This trial studies how different fluids given to treat early sepsis affect the body's fluid balance. Participating may help researchers find better ways to treat sepsis-related low blood pressure and organ failure.
Bucharest, BucharestAges 18 years+ - NCT06505512Recruiting
Belly infection and kidney health ultrasound study
This study uses ultrasound to look at your belly organs and kidney blood flow in people with serious belly infections and sepsis. It may help doctors understand how infection affects the kidneys.
Zhangzhou, FujianAges 14–85 - NCT06516601Recruiting
Severe community-acquired pneumonia observational study
This study looks at patients with severe pneumonia caught outside the hospital. Researchers will review medical records to learn more about how this serious infection progresses.
Trieste, TSAges 18 years+ - NCT06517810Recruiting
QUELIMMUNE pediatric surveillance registry
This registry tracks children treated with QUELIMMUNE therapy to see how well it works over time. It helps doctors learn more about the treatment's safety and effects in kids.
Birmingham, AlabamaAges Up to 22 years - NCT06521502Recruiting
Studying inflammation in the heart and lungs in the ICU
This study collects blood samples from people in the ICU with sudden heart or lung problems caused by inflammation. The goal is to learn more about these conditions and improve future treatments.
Fresno, CaliforniaAges 18 years+ - NCT06545838Recruiting
Testing renin levels to predict septic shock severity
This trial checks if a blood test measuring renin (a kidney hormone) can help predict how severe septic shock will be and how well patients recover. It looks for early clues in ICU patients with sepsis.
MoscowAges 18 years+ - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06572995Recruiting
Fluid monitoring during septic shock recovery
This study is for adults in the intensive care unit with septic shock (a severe infection that drops blood pressure). It looks at how well your body holds fluid and whether treatment can be safely reduced.
BrestAges 18–99 - NCT06601998Recruiting
Heart health after severe pneumonia
This study looks at how heart health changes in people who have recovered from severe pneumonia, including COVID-19. It compares survivors to healthy people and those with heart risk factors.
AlexandroupoliAges 18 years+ - NCT06608849Recruiting
Long-term health effects after COVID-19
This study looks at how COVID-19 may affect the lungs, heart, and kidneys in the months or years after the infection. It compares three groups: people who never had COVID, people who had COVID but recovered without organ problems, and people who had organ problems during COVID. The goal is to understand what long-term complications might arise.
AthensAges 18 years+ - NCT06613256Recruiting
Study of blood vessel cells in different inflammatory conditions
This study looks at blood vessel cells in three groups: healthy adults, patients having major surgery, and critically ill patients with sepsis. It aims to understand how these cells change in different types of inflammation.
Guildford, SurreyAges 18 years+ - NCT06614088Recruiting
Calprotectin blood test for belly infections after surgery
This trial tests whether a blood test called calprotectin can help doctors spot infections in surgical patients with belly problems. It may help doctors decide if you need antibiotics or other treatments.
PisaAges 18 years+ - NCT06624436RecruitingPhase 4
Study of anti-inflammatory drugs in brief, controlled inflammation
This study tests how three different anti-inflammatory drugs (dexamethasone, tocilizumab, and anakinra) affect the body's immune response during a controlled, short-term inflammation. It is for healthy young men who can safely receive an experimental substance that temporarily mimics an infection.
Nijmegen, GelderlandAges 18–35 - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90 - NCT06637904Recruiting
TriVerity blood test for emergency patients with infection
This study tests a new blood test (called TriVerity™) that may help emergency room doctors figure out how sick you are if you have a suspected infection. If you qualify, doctors will check your blood and monitor your recovery through a short phone follow-up.
Peoria, IllinoisAges 18 years+ - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06680180Recruiting
Blood Clot Breakdown in Severe Infection and Injury
This trial studies how well the body's natural clot-busting system works in people with serious infections or major injuries. It may help doctors find better ways to treat these conditions.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06694181Recruiting
Safe and explainable AI for heart, sepsis, and breast cancer patients
This trial uses artificial intelligence (AI) to create prediction models for three groups: cardiology patients, sepsis patients, and breast cancer patients. It aims to make these models safe and easy to understand for doctors.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06709573RecruitingPhase 4
Early vs. late vasopressin for septic shock
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
Cleveland, OhioAges 18 years+
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 268 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.