Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07343206Recruiting
Early norepinephrine for sepsis with low blood pressure
This trial tests whether giving a medicine called norepinephrine early and adjusting the dose quickly can help people with sepsis who have very low blood pressure. It is for adults who are diagnosed within the last 3 hours and who have not already received this medicine.
Bangkok Noi, BangkokAges 18 years+ - NCT06545838Recruiting
Testing renin levels to predict septic shock severity
This trial checks if a blood test measuring renin (a kidney hormone) can help predict how severe septic shock will be and how well patients recover. It looks for early clues in ICU patients with sepsis.
MoscowAges 18 years+ - NCT06791889Recruiting
Tracking bacteria in blood of ICU sepsis patients
This study uses a highly sensitive blood test (DdPCR) to quickly find and monitor harmful bacteria in ICU patients with sepsis, aiming to improve early detection and treatment.
WuhanAges 18 years+ - NCT07287332Recruiting
BLOOM: Testing cefepime dosing in the ICU
This trial tests a way to give the antibiotic cefepime to ICU patients. It aims to see if the dosing can be adjusted more precisely for each person.
Rochester, MinnesotaAges 18 years+ - NCT07286643Recruiting
Ultrasound-guided sepsis care for patients with cirrhosis
This study tests whether using a special ultrasound of the heart can guide treatment for sepsis-related low blood pressure in patients with cirrhosis. It aims to improve care and outcomes for critically ill patients.
ChandigarhAges 18–65 - NCT05694624Recruiting
Study of sepsis-related kidney injury monitoring
This trial looks at acute kidney injury that can happen during sepsis (a serious body-wide infection or suspected infection). It may help improve how doctors detect and manage kidney problems early, especially in intensive care or around major surgery.
Tromsø, TromsAges 18–100 - NCT07273071RecruitingPhase 4
N-acetylcysteine for severe infections
This trial tests if N-acetylcysteine, a medicine that helps the liver and fights inflammation, can improve outcomes for adults with a severe infection and liver stress.
CopenhagenAges 18 years+ - NCT06898723RecruitingPhase 4
Shenfu injection to prevent heart problems in sepsis
This trial tests whether Shenfu injection can help prevent heart muscle damage in people with septic shock. If you have septic shock, you may be able to join this study to see if this treatment helps protect your heart.
Wuhu, AnhuiAges 18 years+ - NCT07232342Recruiting
Blood test for predicting sepsis outcomes after abdominal surgery
This trial tests whether a simple blood test (the capillary leak index) can help doctors better predict how sepsis will progress in people recovering from abdominal surgery. If you are in the ICU after surgery for an abdominal infection, this study may help guide your care.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT06072430RecruitingPhase 3
Testing a new fluid for septic shock with low blood pressure
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
Chandler, ArizonaAges 18 years+ - NCT07225257Recruiting
Recovering Physical Function After ICU Stay in Older Adults
This study looks at how to help older adults regain physical strength after a serious illness that required time in the ICU. It aims to find the best ways to help you recover daily activities like walking and moving around.
Lexington, KentuckyAges 18–99 - NCT06928649Recruiting
Studying cell damage in critically ill ICU patients
This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.
EdegemAges 18 years+ - NCT07211620Recruiting
Using procalcitonin blood tests to guide antibiotic decisions in the ICU
This study compares two ways of using a blood test called procalcitonin to decide when to start antibiotics in critically ill patients with a new infection. The goal is to reduce unnecessary antibiotic use while still effectively treating infections.
BudapestAges 18 years+ - NCT07179276Recruiting
Testing CO₂ gap to guide septic shock treatment
This trial checks if measuring the carbon dioxide gap (a sign of how well blood is flowing to organs) can help doctors improve treatment for people in septic shock. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AngersAges 18 years+ - NCT07134751Recruiting
Febrile Infants Swedish Study
This study looks at babies 60 days or younger who have a fever of 100.4°F or higher. It aims to better understand and manage fevers in young infants.
GothenburgAges Up to 2 months - NCT07109856Recruiting
A new tool to predict infection in newborns
This study tests a simple non-invasive score that uses blood flow in muscles to predict if a newborn has or will develop high inflammation levels (C-reactive protein). It may help doctors start treatment earlier in babies with breathing problems.
Graz, StyriaAges birth–6 hours - NCT07107555Enrolling by invitation
Study of severe tissue infections
This trial studies a rare but serious infection called necrotizing soft-tissue infection (NSTI), which destroys tissue quickly. It looks at how patients are treated in hospitals across Europe to improve care.
BarcelonaAges 18 years+ - NCT05575024Recruiting
Monitoring blood pressure and heart rhythm during kidney support in sepsis
This study looks at how stable blood pressure and heart rhythm are in people with sepsis who need continuous kidney filtration. If you qualify, it may help researchers better improve care for critically ill patients receiving this treatment.
SeoulAges 18 years+ - NCT07067866RecruitingPhase 3
Best way to stop vasopressin in sepsis patients
This trial compares two ways to safely stop the vasopressin medication in people with sepsis who are in the ICU. It aims to find the best approach to wean off this blood pressure support, which could help you recover more smoothly.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07068022Recruiting
Organ function score for pregnant and new mothers in ICU
This study is testing a new way to measure how well your organs are working if you are pregnant or have recently given birth and need care in the intensive care unit (ICU). The goal is to improve monitoring and treatment for mothers in critical care.
Avellaneda, Buenos AiresAges 18 years+ - NCT05349370Recruiting
Track how lactate levels change in septic shock
This study measures how quickly a blood marker called lactate rises or falls in people with septic shock. It may help doctors understand which patterns are linked to recovery and guide better treatment decisions.
Stockholm, Stockholm CountyAges 18 years+ - NCT07063095RecruitingPhase 3
Testing two antibiotics combined for serious bacterial infections
This study tests whether combining two antibiotics (ceftazidime and fosfomycin) works better than ceftazidime alone for hospitalized adults with serious bacterial infections. If you have a severe infection thought to be caused by Gram-negative bacteria, this trial may offer a new treatment option.
Geneva, Canton of GenevaAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06973174Recruiting
B. cereus infections in premature newborns
This study looks at a type of bacterial infection (Bacillus cereus) that can affect the blood or brain lining in premature babies. It helps doctors learn more about these infections so they can improve care.
Nice, Alpes MaritimesAges Up to 5 months
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.