Clinical trials
Sepsis clinical trials
Below are recruiting sepsis clinical trials, each written for real people, not researchers. We’re tracking 267 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT06527443Recruiting
Arterial stiffness in adults with sepsis
This study measures how stiff your arteries are during sepsis, which may help doctors understand your condition better. You need to be an adult in the ICU with sepsis and be tested within 24 hours.
AsyutAges 18 years+ - NCT06143137Recruiting
Long-term recovery after septic shock treatment
This study checks on people who had septic shock and were in the ReActIF-ICE trial. It looks at how their immune system recovered over time after an experimental therapy.
MagdeburgAges 18–80 - NCT07788144Enrolling by invitation
Blood-cleaning therapy for severe belly infections
This study tests a blood-cleaning treatment to remove harmful toxins from the blood of people with severe abdominal infections. It might help their organs recover faster.
SeoulAges 18 years+ - NCT07779720Recruiting
Personalized fluids for emergency sepsis care
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
Murray, UtahAges 18 years+ - NCT07774962Recruiting
Comparing fingertip refill time and blood oxygen use in septic shock
This study looks at two ways to check blood flow and oxygen use in people with septic shock, a severe infection-related condition. It aims to see if a simple bedside test (fingertip refill) and a blood measure (oxygen extraction ratio) agree, which could help guide treatment.
IstanbulAges 18 years+ - NCT06613256Recruiting
Study of blood vessel cells in different inflammatory conditions
This study looks at blood vessel cells in three groups: healthy adults, patients having major surgery, and critically ill patients with sepsis. It aims to understand how these cells change in different types of inflammation.
Guildford, SurreyAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT07739004Recruiting
Fever in Children: Predictors of Serious Illness
This study looks at children with fever to find early signs that might predict serious illness, helping doctors make better triage decisions in the emergency room.
Kayseri, TalasAges birth–18 years - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT07716956Recruiting
Magnesium therapy for severe septic shock
This trial tests whether raising magnesium levels in the blood to a normal upper range can help reduce the need for strong blood pressure medications in people with severe septic shock. It might help stabilize blood pressure and improve recovery.
Alexandria, Alexandria GovernorateAges 18 years+ - NCT07680816Recruiting
Study of gamma delta T cells in critically ill patients
This study looks at a type of immune cell called gamma delta T cells in patients who are very sick in the ICU, including those with and without sepsis. The goal is to understand how these cells work differently in these patients, which could help find better treatments.
Wuhan, Outside of the USAges 18–80 - NCT06680180Recruiting
Blood Clot Breakdown in Severe Infection and Injury
This trial studies how well the body's natural clot-busting system works in people with serious infections or major injuries. It may help doctors find better ways to treat these conditions.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT07653568Recruiting
Comparing two ultrasound methods to guide fluid therapy in septic patients on ventilators
This study tests whether a neck ultrasound (carotid Doppler) or a heart ultrasound (echocardiography) is better at determining how much fluid a septic patient on a ventilator needs. If you or your loved one is in the ICU with sepsis on a breathing machine, this trial helps doctors choose the best way to give fluids that can improve blood pressure and organ function.
Islamabad, Federal AreaAges 12 years+ - NCT07629154Recruiting
Safe Hospital Discharge Planning for Children
This study tests a new discharge process to help children recover safely at home after being treated in the hospital for an infection. The goal is to make sure children get the right follow-up care and support after they leave the hospital.
San Francisco, CaliforniaAges 5–16 - NCT06476171Recruiting
Blood test study for heart surgery patients
This study looks at blood test results from people having heart surgery with a heart-lung machine. It will help doctors understand and improve the use of these tests.
MoscowAges 18–80 - NCT07616817Enrolling by invitation
Expert Panel Study on Ultrasound Assessment of Septic Shock
This study gathers expert opinions from critical care doctors and specialists around the world who use bedside ultrasound (a portable imaging tool) to diagnose and categorize septic shock (a life-threatening infection condition). The goal is to develop standardized approaches to identifying different types of septic shock using ultrasound.
Albany, New YorkAges Any age - NCT06253325Recruiting
Early detection of patients at risk for sepsis
This trial is looking for patients who have an infection and are showing early signs of getting sicker, like a high warning score. It aims to find out if doctors can identify those at risk of sepsis sooner so they can start treatment earlier.
Southampton, HampshireAges 18 years+ - NCT07601711Recruiting
Sulbactam-Durlobactam for Drug-Resistant Bacterial Infections
This study tracks hospitalized patients receiving a specific antibiotic combination (sulbactam-durlobactam) to treat a serious, hard-to-treat bacterial infection called CRAB. Researchers want to understand how well this treatment works in real-world hospital settings.
Chengdu, SichuanAges 18 years+ - NCT07597122Recruiting
Blood markers study in septic shock patients
This research study measures special blood markers (microRNAs) in patients with septic shock or critical illness to understand how the body responds to severe infection. Results may help doctors better diagnose and treat sepsis in the future.
BernAges 18 years+ - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT06372444Recruiting
Kidney injury in severe infections study
This study looks at how severe infections like sepsis can hurt the kidneys. By using special scans (PET-CT), researchers hope to better understand why this happens, which could lead to better treatments.
UppsalaAges 30 years+ - NCT07582926Recruiting
Cortisol Levels and Outcomes in Critically Ill Infection Patients
This study examines how the body's stress hormone (cortisol) relates to survival in patients with severe blood infections in the ICU. Understanding this relationship may help doctors better predict and manage outcomes in critically ill patients.
AnkaraAges 18 years+
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Common questions
- Are there clinical trials for sepsis?
- Yes. Clin2 currently lists 267 recruiting sepsis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.