Clinical trials
Severe Traumatic Brain Injury clinical trials
Below are recruiting severe traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 234 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06571032Recruiting
EEG guidance for brain stimulation after severe injury
This study tests whether using brain wave monitoring (EEG) can help guide electrical stimulation treatment for people with severe traumatic brain injury. It aims to see if this approach can improve recovery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07625995RecruitingPhase 2
Fluid management strategies for traumatic brain injury patients
This study tests two different approaches to managing fluids given to brain injury patients in the ICU—one more restrictive and one more liberal—to see which is safer and more effective. The goal is to find the best balance that protects the brain while supporting overall health.
BrusselsAges 18 years+ - NCT04331392Recruiting
Online memory training for people with recent brain injury
This trial tests an online memory program for people with a recent traumatic brain injury (TBI) to help with thinking and memory. It may be useful if your injury is recent and you can safely do MRI scanning.
Toronto, OntarioAges 18–55 - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80 - NCT06184295Recruiting
Robotic balance training for better balance after brain injury
This study tests whether training on a robotic device can help improve balance and posture for people who had a traumatic brain injury (TBI) within the last 6 months to 5 years. It may help if you have some balance issues and can stand without support for 5 minutes.
West Orange, New JerseyAges 18–65 - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT07560631Recruiting
Facial Tracking to Monitor Brain Injury Recovery
This study uses camera technology to track subtle facial movements as a way to detect awareness and recovery in people with severe brain injuries. It may help doctors better understand and monitor patients who have suffered traumatic brain injury.
Stony Brook, New YorkAges 22–85 - NCT07549529Recruiting
Balance and Movement Problems After Concussion
This study looks at why some people have trouble with balance and movement after a concussion (mild traumatic brain injury). Researchers will test your balance and movement to understand these problems better and help improve how doctors treat them.
Portland, OregonAges 18–60 - NCT07490418Recruiting
Brain injury screening for mild head trauma or neurological symptoms
This trial tests a device (TES HT100) to screen for brain injuries in people with mild head trauma or certain neurological symptoms. It aims to quickly identify who might need imaging or follow-up care.
Castel Volturno, CEAges 18 years+ - NCT07485361Recruiting
Brain scanning in disorders of consciousness
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
Los Angeles, CaliforniaAges 18 years+ - NCT07473505Recruiting
Nerve block for PTSD in special operations veterans
This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.
Strongsville, OhioAges 18 years+ - NCT07463027Enrolling by invitation
Veteran brain injury rehab with integrated care
This trial tests a 3-week rehabilitation program for veterans with traumatic brain injury and other conditions. It aims to improve recovery through team-based care.
Milwaukee, WisconsinAges 18–65 - NCT06816199Recruiting
Hyperbaric oxygen for traumatic brain injury recovery
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) helps people recover from traumatic brain injury. It aims to see if this treatment is safe and can improve healing for patients starting rehabilitation.
Hangzhou, ZhejiangAges 18–90 - NCT07413562Recruiting
Nerve stimulation for memory problems after brain injury
This trial tests whether stimulating a nerve in the wrist (median nerve) can help improve thinking and memory problems in people who have had a recent traumatic brain injury. It is for adults with moderate injuries who have trouble with memory and thinking.
Beijing, Beijing MunicipalityAges 18–64 - NCT07404761Recruiting
Moving your arm after stroke or TBI
This study tests a device that uses mild electrical pulses and augmented reality (a computer overlay on real life) to help people who have arm or hand weakness after a recent stroke or brain injury regain movement.
HaifaAges 18 years+ - NCT05885529Recruiting
Blood and CT tests after a concussion to track brain injury
This study checks whether two blood proteins (GFAP and UCH-L1) can help identify which brain spots are linked to a significant head injury after a concussion. You may be able to help by providing a blood sample and getting a CT scan as part of usual care, so doctors can better sort out injury risk.
AngersAges 18 years+ - NCT07385105Recruiting
CBT for insomnia after mild brain injury
This study tests whether a type of talk therapy called cognitive behavioral therapy for insomnia can help people with mild traumatic brain injury sleep better. It focuses on those who have had sleep problems for over a month.
Columbia, MissouriAges 18–60 - NCT06127459Recruiting
Virtual reality to help kids with brain injury improve thinking skills
This trial tests if virtual reality exercises can help children aged 8-12 with mild or moderate traumatic brain injury improve their attention and thinking skills. It is designed for children whose challenges were confirmed by a psychologist and who speak Finnish.
OuluAges 8–12 - NCT07356167Recruiting
Neurosensory training for mild brain injury symptoms
This study tests a special training program that uses sound and head movements to help people with long-lasting symptoms after a mild brain injury or sudden sensory event. The goal is to see if this 'neurosensory' training can reduce problems like dizziness, headache, and brain fog.
Miami, FloridaAges 18 years+ - NCT07357090Recruiting
Carbon dioxide and brain waste clearance trial
This trial tests if breathing in carbon dioxide helps the brain clear waste. It may show how the brain heals after a traumatic brain injury (TBI).
Albuquerque, New MexicoAges 18–82 - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT07341074Recruiting
Early help for adults with mild traumatic brain injury
This study tests if offering early support soon after a mild head injury can help reduce ongoing symptoms. If you've recently had a mild traumatic brain injury (concussion) and are still having trouble, this program might help you recover better.
GroningenAges 18–70 - NCT06873477Recruiting
Brain injury study for children and young adults
This study looks at children and young adults who have brain damage from a severe head injury or lack of oxygen at birth. It aims to learn more about these conditions and how to help patients.
Rome, LazioAges Up to 20 years
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Common questions
- Are there clinical trials for severe traumatic brain injury?
- Yes. Clin2 currently lists 234 recruiting severe traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.