Clinical trials
Severe Traumatic Brain Injury clinical trials
Below are recruiting severe traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 234 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06036147Recruiting
Concussion Recovery Program for Teens
This study tests a remote program to help teens ages 11 to 18 recover from a concussion that happened 1 to 12 months ago. You'll learn ways to manage symptoms like headaches, tiredness, or trouble focusing, all from home.
Dallas, TexasAges 11–18 - NCT07292766Recruiting
Metabolic Profiles After Severe Head Injury
This study looks at chemical changes in the body after a severe head injury. It aims to find markers that may help guide treatment.
Aksaray, AnkaraAges 18–65 - NCT07269457RecruitingPhase 2
Vitamin D3 for recovery after mild to moderate brain injury
This trial tests if taking vitamin D3 can help reduce swelling and speed up recovery after a mild to moderate traumatic brain injury. It is for people who have low vitamin D levels.
LagosAges 18–65 - NCT05307640Recruiting
Support for caregivers after moderate to severe brain injury
This study tests a caregiver-focused program to improve well-being for people caring for someone who recently had a moderate to severe traumatic brain injury. It may help caregivers feel better and cope more effectively during the early recovery period.
Cincinnati, OhioAges 18 years+ - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT06560372Recruiting
Bleeding after head injury and brain blood vessel narrowing
This study looks at whether moderate to severe traumatic brain injury with bleeding around the brain can lead to a complication called cerebral vasospasm (narrowing of brain blood vessels). It's being done at Martinique University Hospital to understand how often this happens and how it affects recovery.
Fort-de-FranceAges 18 years+ - NCT05233475Recruiting
Rehab program after concussion in Danish adults
This trial tests a “get going” rehabilitation program for people who recently had a concussion (mild brain injury) from a head impact. It may help reduce concussion symptoms and improve day-to-day functioning in the months after injury.
Hammel, Deb´nmarkAges 18–60 - NCT06836856RecruitingPhase 1/Phase 2
Beta blockers after traumatic brain injury: a study
This trial tests whether giving a beta blocker drug after a moderate or severe traumatic brain injury can improve recovery. It is for patients who have a brain injury but only minor or no other injuries.
ZagazigAges 18–75 - NCT07237386Recruiting
Testing a smart insole for walking in people with brain or spinal cord injury
This study tests a special insole that measures how you walk, compared with a high-tech walking lab. It's for people with stroke, spinal cord injury, or brain injury who can walk on their own for 6 minutes.
GhentAges Any age - NCT07230002Recruiting
Navigating in virtual worlds after brain injury
This study looks at how people who had a moderate or severe traumatic brain injury at least 3 months ago walk and navigate in complex virtual environments. Participants will use virtual reality to test their movement strategies.
RennesAges 18–55 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT06851156Recruiting
Brain stimulation for disorders of consciousness after severe injury
This trial tests a new type of brain stimulation called transcranial temporal interference stimulation to see if it can help people with severe brain injury who are in a vegetative or minimally conscious state. It uses gentle electrical currents to try to improve awareness and recovery.
Xi'an, ShaanxiAges 18–65 - NCT06867666Recruiting
Behavioral sleep therapy for insomnia in Navy members with TBI
This study tests a behavioral talk therapy for insomnia (CBT-I) in active duty Sailors who also have a history of traumatic brain injury. You'll learn better sleep habits using an app and coaching, with the goal of improving your sleep and recovery.
San Diego, CaliforniaAges 18 years+ - NCT07180277RecruitingPhase 4
Steroid treatment for moderate to severe brain injury
This trial tests a steroid medicine called methylprednisolone to see if it can help people who have had a moderate to severe brain injury. It aims to reduce swelling in the brain and possibly improve recovery.
Suzhou, JiangsuAges 18–65 - NCT06162091Recruiting
Understanding recovery after severe brain injury
This study is for adults who recently had a severe brain injury (within the last 3 months) and are in the early stages of recovery. Researchers want to learn more about what affects recovery and how to improve outcomes.
MessinaAges 18 years+ - NCT06103201RecruitingPhase 1
Special MRI for Traumatic Brain Injury Recovery
This trial uses a special MRI scan to look at how your brain uses energy after a traumatic brain injury. The goal is to better understand brain healing and find new ways to help people recover.
Baltimore, MarylandAges 18–80 - NCT07119827Recruiting
Personality traits and recovery after brain injury
This study looks at how your personality might affect recovery after a serious brain injury or stroke. You and a family member will answer a short personality questionnaire to see if certain traits are linked to better recovery.
Verona, VRAges 18–80 - NCT07115459Recruiting
Brain Monitoring to Predict Recovery After Acute Brain Injury
This study is testing a new way to predict recovery for people with serious brain injuries in the ICU. It uses continuous brain monitoring to gather more information and help doctors make better treatment decisions.
Changsha, HunanAges 18–80 - NCT07097792Recruiting
Concussion recovery support program for headaches
This study tests a support program for young people who have had a concussion and are still having headaches. It aims to help them recover and feel better.
Seattle, WashingtonAges 18–29 - NCT07105358Recruiting
Vision recovery study after brain damage
This study tests whether the brain can improve vision after damage caused by stroke, tumor, or injury. It may help people with vision loss from a brain lesion find new ways to see better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07092423Recruiting
Special liquid tube feed for brain injury patients
This study tests a special liquid formula (semi-elemental nutrition) given through a feeding tube to people with severe traumatic brain injury. It aims to see if this formula is easier on the stomach and causes fewer digestive problems than standard tube feeds.
Xi'an, ShaanxiAges 18–75 - NCT07072624RecruitingPhase 4
Preventing seizures after severe head injury
This trial tests whether giving medication right after a serious head injury can prevent early seizures. It may help people with certain types of brain injuries seen on CT scans.
Chandigarh, PunjabAges 18–70 - NCT07074938Recruiting
Traditional Chinese medicine for brain injury recovery
This trial tests whether a traditional Chinese medicine called An Gong Niuhuang Wan can help people recover brain function after a traumatic brain injury and surgery. It may be a good fit if you are moderately affected (GCS 6–12) and your condition is stable enough to start treatment within three days.
Wuhan, HubeiAges 18–60 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for severe traumatic brain injury?
- Yes. Clin2 currently lists 234 recruiting severe traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.