Clinical trials
Shock clinical trials
Below are recruiting shock clinical trials, each written for real people, not researchers. We’re tracking 313 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06308055Recruiting
Impella heart pump study in ICU
This study is for people in the intensive care unit who are using a heart pump called Impella. It will collect information about how well the heart pumps blood during treatment to help doctors learn more.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT06178822Recruiting
New blood tests to diagnose sepsis in the ER
This study aims to find new ways to quickly diagnose sepsis (a severe response to infection) in patients arriving at the emergency room. If successful, these new tests could help doctors start treatment faster.
Almere Stad, FlevolandAges 18 years+ - NCT06193980Recruiting
ICU recovery exercise test study
This trial looks at how well your heart and lungs work together after a long stay in the ICU on a breathing machine. It uses a simple exercise test to check your recovery after leaving the hospital.
Winnipeg, ManitobaAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT06070350RecruitingPhase 3
Massive transfusion for life-threatening bleeding in children
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Tucson, ArizonaAges Up to 17 years - NCT05913622Recruiting
Testing heart pump unloading during VA ECMO in adults
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
BrugesAges 18 years+ - NCT05907239Recruiting
Shock wave therapy for jaw muscle pain
This trial tests whether focused shock wave treatment can reduce chronic jaw pain caused by jaw muscle problems. You might qualify if you have moderate to severe temporomandibular (jaw) pain for at least 3 months.
São Paulo, São PauloAges 18 years+ - NCT05817851RecruitingPhase 2
Vitamin C by vein after cardiac arrest shock
This Phase 2 study tests whether early high-dose vitamin C given through a vein can improve outcomes for people who remain unconscious after an out-of-hospital cardiac arrest with shock. It may help by supporting recovery during the time when the body is under severe stress.
AmiensAges 18 years+ - NCT05788120Recruiting
Study heart rhythm problems in adults on VA ECMO
This study looks at how often abnormal heart rhythms happen and how serious they are in adults who are supported with VA ECMO for severe heart failure. It mainly involves using medical information, aiming to better understand complications in this critical situation.
AngersAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT05534971RecruitingPhase 4
Testing safer ultrasound-guided central line placement in the ER
This Phase 4 study looks at how to place a large IV line (called a central line) in the emergency department using ultrasound guidance. It may help patients by improving how safely and effectively these lines are placed, especially in urgent situations.
The Bronx, New YorkAges 18 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05304728Enrolling by invitation
Hospital sepsis decision support program enrollment study
This study tests a computer system meant to help doctors recognize and manage sepsis (a serious body-wide response to infection) when people come to the emergency department or are admitted to the hospital. If you’re evaluated in a hospital setting for possible sepsis, you may be included to help improve care decisions.
Irvine, CaliforniaAges 18–89 - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99 - NCT04972526Recruiting
Registry for adult patients who get an ultrasound heart scan in ICU
This study is a registry, meaning it collects information from adult patients who—during routine emergency care in the ICU—receive a focused ultrasound of the heart (a test called TEE). It helps doctors learn how this test is used and what outcomes follow, with no extra treatment required.
Chicago, IllinoisAges 18 years+ - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT04770584Recruiting
Fear and avoidance study in PTSD and healthy volunteers
This study looks at how people with current PTSD—or people without PTSD—respond to fear and avoiding things they might find threatening. It may help researchers understand these patterns and how they differ after trauma.
Houston, TexasAges 18–70 - NCT02118467RecruitingPhase 4
Testing medicines that raise blood pressure in ICU shock patients
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
Chicago, IllinoisAges 18 years+ - NCT04295252Recruiting
Altshock-2 registry for people with cardiogenic shock
This study is a “registry,” meaning it collects health information from people hospitalized with cardiogenic shock. It may help doctors better understand the condition and improve care over time.
MilanAges 18 years+ - NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT04203979Recruiting
Sepsis care tailored to patients
This study looks at how to better recognize and manage sepsis (a serious body-wide reaction to infection) and tailor care to the individual. You may be eligible if you are newly admitted to the emergency department and your care is handled by a rapid response team for sepsis.
OsloAges 18 years+ - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+
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Common questions
- Are there clinical trials for shock?
- Yes. Clin2 currently lists 313 recruiting shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.