Clinical trials
Shoulder clinical trials
Below are recruiting shoulder clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06992375Recruiting
Shoulder manipulation study for volleyball players
This trial tests a shoulder manipulation technique in healthy volleyball players to see if it improves shoulder function and performance. It may help if you play regularly and haven't had recent injuries or surgeries.
GdanskAges 18–30 - NCT05848375Recruiting
Rotator cuff surgery done with special anesthesia alone
This trial studies rotator cuff repair surgery when the surgeon uses a regional anesthesia method (numbing the arm area) rather than general anesthesia alone. It may help people with certain types of rotator cuff tendon injuries who are good candidates for outpatient surgery and this anesthesia approach.
NantesAges 18 years+ - NCT05351112Recruiting
Shoulder fracture replacement study for adults using a Zimmer Biomet system
This trial studies how safe and well a specific shoulder replacement system works after certain serious shoulder injuries or failed prior treatments. You may be considered if you need shoulder surgery for complex proximal humerus fractures or related post-injury problems, and you can return for follow-up visits.
SalamancaAges 18 years+ - NCT04728282Recruiting
RTSA surgery with or without repairing the subscapularis
This study compares two surgical approaches for RTSA (reverse shoulder replacement): doing a tendon repair on the front of the shoulder or not. It may help show which approach leads to better recovery and shoulder function for people who need their first RTSA.
Winnipeg, ManitobaAges 18 years+ - NCT04949087Recruiting
Shoulder arthritis injection study for ongoing pain relief
This trial looks at how well medicine given directly into the shoulder joint reduces pain from primary shoulder osteoarthritis. If you have ongoing shoulder pain confirmed by X-ray, you may be eligible to receive an in-joint injection and be followed for response.
Chicago, IllinoisAges 18 years+ - NCT03711175Enrolling by invitation
Repairing a shoulder tendon after reverse shoulder replacement
This study looks at whether repairing a specific shoulder tendon (the subscapularis) improves outcomes after reverse shoulder replacement. You may be eligible if you’re getting a reverse shoulder implant because of severe arthritis and your tendon is strong enough to repair on MRI.
St Louis, MissouriAges 21 years+ - NCT04028401RecruitingPhase 3
Skin prep study to reduce bacteria in shoulder replacement surgery
This study tests whether a specific skin-cleaning method before shoulder replacement surgery can reduce a common bacteria (Cutibacterium acnes) found on skin and deeper samples. It may help lower the risk of infection or contamination during prosthetic shoulder surgery.
AngersAges 18 years+ - NCT02996656Recruiting
Antibiotic prevention for skin bacteria in shoulder surgery
This study checks whether giving an antibiotic “ahead of surgery” can reduce problems from common skin bacteria (Propionibacterium acnes) during primary shoulder surgery. It may help lower the risk of infection around the new joint/repair.
Montreal, QuebecAges 18 years+ - NCT02503228Enrolling by invitation
Registry study of a preserved bone-cartilage graft
This registry study follows people who get a preserved graft to repair damaged bone and cartilage in a joint. It helps doctors understand how well the graft is preserved and how patients do after surgery over time.
Columbia, MissouriAges 13 years+ - NCT06162858Recruiting
Study on arm motion after reverse shoulder replacement
This study looks at how well people can move their arms during daily activities after having a reverse shoulder replacement. It may help find ways to improve recovery and function.
GhentAges 60 years+ - NCT06268795Recruiting
Comparing biopsy vs. aspiration for shoulder/elbow revision surgery
This study compares two methods—biopsy (taking a small tissue sample) and aspiration (drawing fluid)—to see which one better detects infection in people having repeat shoulder or elbow replacement surgery. The results will help doctors choose the best test for future patients.
Wigan, LancashireAges 18 years+ - NCT05030220Recruiting
Testing testosterone and a skin bacteria during shoulder surgery
This study looks at how testosterone levels and a common skin bacteria (Cutibacterium) may relate to outcomes around elective shoulder replacement surgery. Results could help improve how doctors prevent and understand infection risk or healing after surgery.
Seattle, WashingtonAges 18–89 - NCT06741527Recruiting
Integrity Implant for rotator cuff repair study
This study is testing a new shoulder implant called the Integrity Implant System to see how well it works for people with rotator cuff tears. It may be a good fit if you need surgery to repair your torn tendon and meet the safety requirements.
Gilbert, ArizonaAges 18 years+ - NCT07537127Recruiting
Lidocaine to reduce shoulder pain after single-port surgery
This trial tests whether lidocaine (a numbing medication) injected during a minimally invasive single-port abdominal surgery can reduce shoulder pain after the procedure. Shoulder pain is a common side effect of this type of surgery, and the study aims to find a simple way to prevent it.
Beijing, Beijing MunicipalityAges 18–65 - NCT07553611Recruiting
Regional anesthesia and shoulder surgery recovery outcomes
This study compares different numbing techniques used during shoulder arthroscopy (a minimally invasive shoulder surgery) to see which one helps patients recover better, use less pain medication, and experience fewer complications like temporary paralysis of the breathing muscle under the rib cage.
Antalya, MuratpaşaAges 18–65 - NCT05898243Recruiting
Study of injuries after shoulder dislocation in adults over 40
This study follows people over age 40 who have their first traumatic “front” shoulder dislocation to learn what injuries happen and how they can be identified. It may help doctors better understand what to check for after this kind of injury.
Sabadell, BarcelonaAges 40 years+ - NCT07094178Recruiting
Steroid vs PRP shots for shoulder tendon pain
This trial compares two treatments for shoulder tendinopathy: a corticosteroid shot or a platelet-rich plasma (PRP) injection. It aims to find which one works better to relieve pain and improve function.
TunisAges 18 years+ - NCT06741579RecruitingPhase 3
Pain relief study for nerve injury pain
This trial tests how well two types of peripheral nerve stimulation (PNS) devices relieve chronic pain caused by a single nerve injury. It looks for people who already have a referral for PNS therapy as part of their usual care and who have gotten at least 50% relief from a diagnostic nerve block.
Palo Alto, CaliforniaAges 18 years+ - NCT07689045Recruiting
Comparing two nerve blocks for shoulder surgery pain
This trial compares two types of nerve blocks for pain control during and after Bankart or Latarjet shoulder surgery. The goal is to see which block provides better pain relief and preserves arm strength.
Cairo, Cairo GovernorateAges 18–65 - NCT06681311Recruiting
Core and shoulder exercises for master swimmers
This study tests whether adding core and shoulder stabilization exercises to swimming training can improve athletic performance and lower injury risk in master swimmers. It may help you swim stronger and stay injury-free.
Istanbul, MaltepeAges 25–50 - NCT06025448Recruiting
Comparing two types of reverse shoulder replacement
This study compares two types of reverse shoulder replacements: one that uses a small piece of your own bone (BIO-RSA) and another that uses a special metal implant (MIO-RSA) to fill the socket. The goal is to see which one stays more stable in the bone after surgery.
OsloAges 45–80 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT05675527RecruitingPhase 4
Platelet gel (PRP) for shoulder arthritis pain
This trial tests whether platelet-rich plasma (PRP), a blood-based treatment, can reduce pain from shoulder (glenohumeral) osteoarthritis. It also looks at whether PRP works for people who had temporary relief from a numbing/shock injection into the joint.
New York, New YorkAges 18–100 - NCT05677152RecruitingPhase 2
Anti-bone-drug test to help shoulder tendon healing after surgery
This Phase 2 trial studies whether an anti-osteoporosis medicine (zoledronic acid) can improve healing after surgery for a chronic rotator cuff tear in the shoulder. If you qualify, you would also follow a specific 4-week physical therapy plan using a shoulder support pad.
ViennaAges 50–70
Hear when a new Shoulder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for shoulder?
- Yes. Clin2 currently lists 349 recruiting shoulder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shoulder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shoulder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.