Clinical trials
Soft Tissue clinical trials
Below are recruiting soft tissue clinical trials, each written for real people, not researchers. We’re tracking 323 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07293702Recruiting
IASTM therapy for shoulder pain from impingement
This study tests a hands-on therapy called IASTM (instrument-assisted soft tissue mobilization) to see if it can reduce pain, improve movement, and help your shoulder feel more stable. It is for people with subacromial impingement syndrome, a common cause of shoulder pain.
IstanbulAges 40–60 - NCT07602049RecruitingPhase 2
Freezing Plus Immunotherapy for Advanced Soft Tissue Sarcoma
This trial combines cryoablation (a freezing technique to destroy tumors) with camrelizumab (an immunotherapy drug that helps your immune system fight cancer) for patients with advanced soft tissue sarcoma that hasn't responded to standard treatments. The goal is to see if this combination works better than current options.
Guangzhou, GuangdongAges 14–70 - NCT05146440RecruitingPhase 1/Phase 2
Test drug PM14 alone and with radiation for soft-tissue sarcoma
This early-phase study tests PM14 (a new cancer treatment) to see if it can shrink tumors in soft-tissue sarcoma. Some people also receive radiation, aiming to improve tumor control while keeping side effects manageable.
Zaragoza, AragonAges 18–75 - NCT06603714Enrolling by invitation
Soft tissue massage at different muscle lengths study
This trial tests how soft tissue mobilization affects muscles when stretched compared to relaxed. It may help improve flexibility or recovery in healthy people.
Izola, PrimorskaAges 18–25 - NCT06644287Recruiting
PET scan to track immunotherapy response in advanced sarcoma
This trial uses a special PET scan called 68Ga-grazytracer to see how well your soft tissue sarcoma responds to immunotherapy treatment. It may help doctors understand if the treatment is working.
Shanghai, Shanghai MunicipalityAges 6–80 - NCT06002607Recruiting
Shorter vs longer antibiotics for severe skin infections
This study compares a shorter course (about 7 days) of antibiotics to a longer course (about 14 days) for people who had surgery for a severe skin and muscle infection. The goal is to see if a shorter treatment works just as well.
Orange, CaliforniaAges 18 years+ - NCT06062927Recruiting
Genes and scans predict response to immunotherapy and targeted therapy for advanced sarcoma
This trial is testing whether a combination of two drugs—a targeted therapy (surufatinib) and an immunotherapy (envafolimab)—can help people with advanced soft tissue sarcoma that has spread or cannot be removed by surgery. Researchers will also use a person's genetic information and scans to see if they can predict who will benefit the most.
Beijing, Beijing MunicipalityAges 18–75 - NCT07330154Recruiting
Gel for Faster Healing After Gum Graft Surgery
This trial tests a new gel (Nano Bio Fusion Gingival Gel) to see if it helps the roof of your mouth heal faster after a gum graft. It compares the gel to a placebo (inactive gel). The study is for people who need gum graft surgery for receding gums.
Irbid, Irbid GovernorateAges 18 years+ - NCT07120386Recruiting
Comparing two wound vacuum methods for severe skin infections
This study compares two wound care methods after emergency surgery for a serious skin infection. One method uses a standard wound vacuum, and the other uses a wound vacuum that also irrigates (rinses) the wound to see if it helps with healing.
Saint Paul, MinnesotaAges 18 years+ - NCT04605770RecruitingPhase 2
Pemetrexed and cisplatin for advanced soft tissue cancer
This Phase 2 trial tests whether pemetrexed plus cisplatin can shrink advanced or metastatic soft tissue sarcoma. It may help people whose cancer has spread and who can safely receive chemotherapy.
SeoulAges 19 years+ - NCT05894018RecruitingPhase 2
Seed radiation plus fluzoparib for advanced soft tissue sarcoma
This trial tests whether combining seed radiation (iodine-125 placed in/near the tumor) with fluzoparib can better control advanced, hard-to-remove soft tissue sarcoma. It may help shrink tumors and slow progression, but you must meet several cancer, health, and safety requirements.
Guangzhou, GuangdongAges 18 years+ - NCT05961761RecruitingPhase 2
Testing propranolol plus pembrolizumab for advanced sarcoma
This Phase 2 trial tests whether combining propranolol (a blood-pressure/heart medicine) with pembrolizumab (an immune therapy) can help people with advanced angiosarcoma or undifferentiated pleomorphic sarcoma that has progressed after first-line chemotherapy. It aims to slow tumor growth and improve outcomes while also studying tumor markers from your biopsy tissue.
AarhusAges 18 years+ - NCT06637007RecruitingPhase 2
Chidamide plus AK112 for advanced sarcoma after first treatment
This trial tests two new drugs (chidamide and AK112) together for people with advanced bone or soft tissue sarcoma that has not responded to standard first-line treatment. The goal is to see if this combination can shrink tumors or slow their growth.
Taiyuan, ShanxiAges 18–75 - NCT06849986RecruitingPhase 2
Immunotherapy & AI for first-line soft tissue sarcoma
This trial tests a combination of immunotherapy (a treatment that helps your immune system attack cancer) and artificial intelligence (AI) technology as the first treatment for certain types of advanced soft tissue sarcoma. It aims to see if this approach can shrink tumors or stop them from growing better than current options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07052383RecruitingPhase 1
DIT309 for advanced bone and soft tissue sarcomas
This trial tests a new cell therapy called DIT309 for people with advanced bone or soft tissue sarcoma that hasn't responded to standard treatments. It aims to see if this therapy is safe and effective.
Shanghai, Shanghai MunicipalityAges 8 years+ - NCT02910895Recruiting
Test of lab-grown sarcoma samples to guide treatment research
This study uses tumor samples from soft tissue sarcoma to create lab models that researchers can test. It may help scientists better understand sarcoma and find more personalized treatment ideas for people like you.
AmsterdamAges 18 years+ - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT06367075RecruitingPhase 2
Cadonilimab plus adriamycin for advanced soft tissue sarcoma
This trial tests a combination of two drugs—cadonilimab (a type of immunotherapy) and adriamycin (chemotherapy)—for adults with advanced soft tissue sarcoma that hasn't been treated before. The goal is to see if this combination helps shrink tumors or slow their growth.
Wuhan, HubeiAges 18–75 - NCT05620693Recruiting
Cell therapy study for NY-ESO-1–positive soft tissue cancer
This trial tests an engineered immune cell treatment (NY-ESO-1 TCR-T) for people with advanced soft tissue sarcoma that has returned or spread after standard treatment. It aims to treat cancer cells that show a specific marker (NY-ESO-1) in the tumor.
Shenzhen, GuangdongAges 18–70 - NCT05876715RecruitingPhase 1/Phase 2
Testing 3 immunotherapy drugs for hard-to-remove soft tissue cancer
This Phase 1/2 study tests lurbinectedin plus two immune checkpoint medicines (ipilimumab and nivolumab) for soft tissue sarcoma that is hard to remove or has spread. It aims to see how well the combination works and how safe it is, especially for people with limited treatment options.
Santa Monica, CaliforniaAges 18–90 - NCT07727434Recruiting
Stress and Anxiety in People Having Biopsy for Bone or Soft Tissue Cancer
This study looks at how stress and anxiety levels change in people who are about to have a biopsy for a possible bone or soft tissue tumor. The goal is to better understand the emotional impact of waiting for results and starting treatment.
IstanbulAges 18 years+ - NCT03967834Recruiting
Study of immune features in rare soft tissue sarcoma
This study looks at immune system “fingerprints” using tumor tissue from people with rare soft tissue sarcoma. It may help researchers understand what drives these cancers and guide future treatments.
BesançonAges 18 years+ - NCT05468970Recruiting
Study of bone and soft tissue tumors and treatment outcomes
This study looks at people with bone or soft tissue tumors to understand their features, treatments used, and survival outcomes. It may help doctors learn which care approaches work best for different tumor subtypes.
Zhengzhou, HenanAges 6–99 - NCT05621668RecruitingPhase 1
First drug trial using engineered T-cells for sarcoma
This Phase 1 trial tests a new immune therapy made from your T-cells and engineered to target sarcoma tumors. It is designed to see if the treatment is safe and whether it can shrink advanced or metastatic soft tissue or bone sarcoma.
Houston, TexasAges 12 years+
Hear when a new Soft Tissue trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for soft tissue?
- Yes. Clin2 currently lists 323 recruiting soft tissue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.