Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05447299Enrolling by invitation
Muscle and spasticity testing using MRI modeling
This study uses an MRI scan and movement measurements to better understand muscle tightness (spasticity) in children with cerebral palsy. It may help researchers improve how spasticity is evaluated and modeled to support future treatments.
StockholmAges 5–18 - NCT05197764Recruiting
Track muscle growth in young children with spastic cerebral palsy
This study looks at how the muscles in the body grow in infants and young children with spastic cerebral palsy (a type of movement difference). It may help doctors better understand normal growth patterns and how care choices affect muscle development.
Leuven, Vlaams-BrabantAges 6 months–9 years - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99 - NCT04752774RecruitingPhase 1/Phase 2
Botox-like injection study for arm spasticity after stroke
This trial tests whether IPN10200, a Botox-like treatment, is safe and helps reduce stiff, tight upper-arm muscles caused by spasticity after stroke or brain injury. You may be able to join if you meet specific timing, prior-treatment, and muscle-stiffness measurements.
Downey, CaliforniaAges 18–70 - NCT03384927Enrolling by invitation
Dairy intake study for muscle stiffness in spasticity
This trial looks at whether eating dairy can reduce spasticity, or muscle stiffness/tightness. It’s testing dairy as an add-on by comparing your muscle symptoms and treatment goals during the study.
Glostrup MunicipalityAges Any age - NCT05497609Recruiting
Study of tiny muscle changes in children with cerebral palsy
This study follows children with cerebral palsy (and sometimes acquired brain injury) to learn how the muscles look and change over time at a very small, microscopic level. The results may help researchers better understand what’s happening in the muscles and guide future treatments.
StockholmAges 2–18 - NCT05506228Recruiting
Muscle biopsy during surgery study in brain injury conditions
This study looks at how muscles are affected in children and teens with cerebral palsy or an acquired brain injury. Researchers take a small muscle tissue sample during surgery that you were already having for medical reasons, to better understand muscle changes.
StockholmAges 2–18 - NCT05518565Recruiting
Study muscle changes in people with cerebral palsy
This study looks at how muscles work in the body in people with cerebral palsy or an acquired brain injury. It may help researchers understand muscle structure and changes over time, which could guide future treatments.
StockholmAges 2–18 - NCT05571033Recruiting
Training the ankle reflex in adults with spastic cerebral palsy
This study tests a method to retrain a reflex in the ankle to help reduce muscle tightness and improve movement in adults with spastic cerebral palsy. You would do controlled practice during the study while your usual medical care stays stable.
White Plains, New YorkAges 18 years+ - NCT07872839Enrolling by invitation
Study of arm muscle activity in spinal cord injury
This study looks at how arm muscles work together in people with spinal cord injury. It involves mild electrical stimulation to help understand muscle control, which may lead to better treatments.
TaipeiAges 20–65 - NCT07686809Recruiting
Leg therapy for children with one-sided weakness
This study tests a new leg exercise program to help children with hemiplegia walk better. The therapy may improve balance and movement in the affected leg.
CairoAges 6–8 - NCT06673849Recruiting
Rhythmic Stabilization vs. Ball Balancing for CP Children
This study compares two therapy techniques—rhythmic stabilization and ball balancing—to see which helps children with spastic diplegia CP improve balance and movement. It's for children aged 6 to 12 with mild spasticity and normal intelligence.
Lahore, Punjab ProvinceAges 6–12 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT06543758RecruitingPhase 4
Gait rehab with a wearable robot at home
This trial tests whether using a wearable robotic device at home can improve walking ability in people who have had a stroke. If you have trouble walking due to a stroke, this study may help you regain strength and mobility.
Yongin-si, Gyeonggi-doAges 19–79 - NCT07595744Recruiting
Sensory Walkway Training for Walking in Children With Cerebral Palsy
This study tests whether a special sensory walkway (a textured surface that stimulates the feet) can help children with diplegic cerebral palsy (a condition affecting movement in both legs) walk better and with improved coordination. The goal is to see if this training improves gait patterns and overall walking ability.
Dokki, Giza GovernorateAges 5–7 - NCT04630873RecruitingPhase 1
Botox dilution options for walking in hemiplegic gait
This Phase 1 study tests whether using a lower or higher dilution of Botox injections improves walking in people with hemiplegic gait. The goal is to see which dilution works better (and is safe) for walking and leg stiffness.
IoanninaAges 18 years+ - NCT07583498Recruiting
Treating Muscle Stiffness After Spinal Cord Injury With Oxygen Therapy
This study tests whether brief periods of low oxygen (called acute intermittent hypoxia) can reduce muscle stiffness and tightness that develops after a spinal cord injury. Researchers believe this approach may help improve arm and hand function.
Chicago, IllinoisAges 18 years+ - NCT06725836Recruiting
Spinal cord stimulation study for spinal cord injury
This study tests how spinal cord stimulation affects brain activity in people with spinal cord injuries. It aims to understand the physiological effects using EEG (a brainwave test).
Vladivostok, Primorskiy (Maritime) KrayAges Any age - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT07516067Recruiting
Spinal Cord Stimulation to Help Children With Cerebral Palsy Move Better
This study tests whether a mild electrical stimulation applied to the skin over the spine can help children with cerebral palsy improve their movement and walking. Researchers will compare children who receive this treatment with children who don't have cerebral palsy to see if it makes a real difference.
Pittsburgh, PennsylvaniaAges 5–17 - NCT07513714Recruiting
Electrical stimulation for arm recovery after stroke
This study tests a therapy using small electrical pulses to help people who have had a stroke move their arm and hand better. It is for people who already receive Botox injections for muscle tightness and have some movement in their arm.
Foggia, FoggiaAges 18–80 - NCT07478172Recruiting
Electrical muscle stimulation exercise for neuromuscular disease
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
Columbia, MissouriAges 18 years+ - NCT07467382Recruiting
Observing Achilles Tendon During Walking
This study observes how the Achilles tendon works during walking in people who have had a stroke, a spinal cord injury, or in healthy volunteers. It aims to better understand gait problems.
NantesAges 18 years+ - NCT07458555Enrolling by invitation
Anesthetic impact on FLIP measurements
This trial looks at how different anesthetics affect FLIP measurements during endoscopy or POEM for esophageal problems. FLIP helps doctors check how well the esophagus opens and closes.
Dallas, TexasAges 18–75
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 153 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.