Clinical trials
Spasticity clinical trials
Below are recruiting spasticity clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06547684Recruiting
Shock wave therapy for foot stiffness after stroke
This trial tests whether shock wave therapy can help relax the tight calf muscles that cause foot drop after a stroke. It may help you walk better and reduce foot stiffness.
Vila-real, CastellonAges 18 years+ - NCT06571929Recruiting
Augmented reality training for arm function in children with cerebral palsy
This study tests whether playing special augmented reality games (where virtual objects appear in the real world) can improve arm and hand function in children with spastic cerebral palsy. It compares game training to usual therapy.
São Carlos, São PauloAges 6–12 - NCT06572046Recruiting
Registry for hereditary spastic paraplegia (HSP)
This registry collects information from people with hereditary spastic paraplegia or spastic ataxia to help plan future treatments. It aims to better understand the condition and connect patients with potential therapies.
PisaAges Any age - NCT06598657Recruiting
Gentle ankle mobilization for spastic cerebral palsy
This study tests a gentle ankle movement therapy to improve walking in children with spastic cerebral palsy. It may help reduce leg stiffness and make walking easier.
Islamabad, Punjab ProvinceAges 8–18 - NCT05518188RecruitingPhase 1/Phase 2
Gene therapy trial for a childhood AP4M1 brain disorder
This trial studies a one-time gene therapy meant to help children with SPG50 disease caused by changes in the AP4M1 gene. Researchers will give the treatment and closely monitor safety and early signs of benefit.
Dallas, TexasAges 4 months–10 years - NCT06674057Recruiting
Taping with physical therapy for arm function after stroke
This study tests whether adding kinesio-taping to standard physical therapy helps improve arm movement and reduce stiffness in people recovering from a recent stroke.
IslamabadAges 40–65 - NCT06674785Recruiting
Shock wave therapy for shoulder spasticity after stroke
This trial tests if shock wave therapy can reduce shoulder stiffness caused by a stroke. It may help improve shoulder movement and daily comfort.
TaipeiAges 18 years+ - NCT06676332Recruiting
Training to improve movement and coordination in children with cerebral palsy
This trial tests whether a special training that combines mental imagery and sensory activities can improve muscle strength and coordination in children who have tight muscles in their legs. It is for children who can walk on their own or with some help.
CairoAges 8–12 - NCT06686719Recruiting
Stretching and relaxation for kids with spastic cerebral palsy
This trial compares three gentle stretching and muscle relaxation techniques to see which one best helps children with spastic cerebral palsy move more easily and feel less stiff. The goal is to find a safe, non-invasive way to improve daily function.
RawalpindiAges 8–18 - NCT07685327Recruiting
Mixed reality vs. physical therapy for balance in teens with cerebral palsy
This study compares two types of therapy to help teens with spastic diplegic cerebral palsy improve their balance and coordination. One group will use mixed reality (a blend of real and virtual environments) and the other group will do standard physical therapy exercises.
Mansehra, KpkAges 10–19 - NCT06726434Recruiting
Comparing freezing vs. surgery for foot spasticity after stroke
This trial compares a freezing procedure (cryoneurotomy) with standard surgery to treat foot stiffness after a stroke. It aims to see which method better corrects the foot turning inward and downward, helping you walk more easily.
GarchesAges 18 years+ - NCT06728787Recruiting
Robot-assisted walking for hereditary spastic paraplegia
This trial tests if robot-assisted walking therapy can help people with hereditary spastic paraplegia (a condition causing progressive leg stiffness and weakness) improve their walking ability. It may be an option if you can walk indoors on your own.
Bosisio Parini, Italy/leccoAges 4–70 - NCT06733025Recruiting
Comparing surgery and Botox for arm spasticity
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
MölndalAges 18 years+ - NCT06742697Recruiting
Exercise program to improve walking in Hereditary Spastic Paraplegia
This study tests a combined exercise program with flexibility, strength, aerobic, and movement training to see if it helps improve walking in adults with Hereditary Spastic Paraplegia. Participants attend at least 10 supervised sessions over several weeks.
Bosisio Parini, LombardyAges 18 years+ - NCT06925425Recruiting
Electrical stimulation for arm skills in children with cerebral palsy
This study tests if a special electrical stimulation therapy, used during specific tasks, can improve arm and hand control in children with spastic quadriplegic cerebral palsy. It aims to help kids with moderate to severe motor challenges gain better use of their upper limbs.
Alexandria, EgyptAges 2–6 - NCT07119801Recruiting
Shock wave therapy for arm stiffness after stroke
This trial tests whether shock wave therapy can help reduce muscle tightness in the wrist and hand after a stroke. It may be an option if you have had one stroke, are between 35 and 65 years old, and still have stiffness that bothers you.
DenizliAges 35–65 - NCT07190092Recruiting
Brain stimulation for post-stroke muscle stiffness and movement
This study tests a new type of brain stimulation (deep anterior cerebellar stimulation) to see if it can reduce muscle stiffness and improve movement in people who had a stroke 9–36 months ago and still have tightness or weakness that hasn't gotten better with therapy.
BydgoszczAges 18 years+ - NCT07202195Recruiting
Using stimulation suits at home for MS symptoms
This trial tests whether wearing a special suit at home can help manage muscle stiffness (spasticity) or lack of coordination (ataxia) caused by multiple sclerosis. The suit delivers gentle stimulation to improve movement in your arms or legs.
SteenokkerzeelAges 18 years+ - NCT07253857Recruiting
Hand and arm therapy for children with cerebral palsy
This study tests a special hand and arm therapy for children with spastic cerebral palsy. The therapy also includes leg exercises to improve movement. It may help your child use their hands and arms better.
Lahore, Punjab ProvinceAges 6–12 - NCT07321158Recruiting
Electrical stimulation for arm spasticity after first injury
This trial tests whether different pulse durations of electrical stimulation (NMES) can reduce muscle tightness (spasticity) in the arm after a first-time brain or spinal cord injury. It uses special brain-wave tests to measure changes.
Athens, AtticaAges 18 years+ - NCT02535936Recruiting
Brain plasticity study after rhizotomy surgery for spastic diplegia
This study looks at how the brain adapts after selective dorsal rhizotomy surgery in children with spastic diplegia. It may help doctors better understand recovery and treatment effects over time.
Houston, TexasAges 3–18 - NCT07438223Recruiting
Brain gym exercises for balance in children with spastic diplegia
This study tests whether simple 'brain gym' exercises can help children with spastic diplegia (a type of cerebral palsy) improve their balance and quality of life. It could be a good option if you have mild muscle stiffness and are between 6 and 8 years old.
Cairo, Faculty of Physical TherapyAges 6–8 - NCT07447934Recruiting
Vibration therapy for leg muscle stiffness
This trial tests if gentle vibrations can reduce muscle stiffness (spasticity) in the lower leg after a neurologic condition like stroke or brain injury. You may join if you've had spasticity for at least 6 months and can stand with or without help.
New York, New YorkAges 18–85 - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12
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Common questions
- Are there clinical trials for spasticity?
- Yes. Clin2 currently lists 154 recruiting spasticity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spasticity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spasticity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.