Clinical trials
Spinal Cord Diseases clinical trials
Below are recruiting spinal cord diseases clinical trials, each written for real people, not researchers. We’re tracking 260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT04196413RecruitingPhase 1
CAR T cell treatment for a specific brainstem glioma mutation
This Phase 1 study tests a custom immune therapy called GD2 CAR T cells in children and adults with a specific type of diffuse midline glioma (DMG) that has the H3K27M mutation. The goal is to see if the treatment is safe and can help control the cancer.
Stanford, CaliforniaAges 2–60 - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT05563103Recruiting
Combination therapy to improve spinal cord injury recovery
This trial studies a combination of treatments to help people with certain types of spinal cord injury regain some movement and feeling over time. If you meet the specific injury and health criteria, you may be asked to do simple walking and assessment tests during treatment.
Chicago, IllinoisAges 18–70 - NCT05534321RecruitingPhase 1/Phase 2
Preventive radiation for high-risk spinal bone metastases
This trial tests whether preventive (before serious problems happen) radiation to the spine can help people with high-risk, mostly symptom-free bone metastases. It may reduce the chance of pain escalation or dangerous complications from cancer in the spine.
Miami, FloridaAges 18 years+ - NCT07299734RecruitingEarly Phase 1
Augmented reality + electrical stimulation for hand grasp
This trial tests a system that combines a video-like overlay (augmented reality) with small electrical pulses to help you grasp objects. It may improve your hand function and control.
Toronto, OntarioAges 18–65 - NCT06553469Recruiting
Sacral nerve modulation for bladder and bowel problems after spinal cord injury
This trial tests if sacral nerve modulation can improve bladder and bowel control in people with spinal cord injury. Patients receive a temporary stimulator first, and if it helps, they may get a permanent implant.
Jinan, ShandongAges 18 years+ - NCT06611748Recruiting
Hand function restoration after spinal cord injury
This trial tests a device to help people with cervical spinal cord injury improve hand function. It's for those with certain levels of paralysis and some residual arm strength.
Cleveland, OhioAges 18 years+ - NCT06486038Recruiting
Spinal cord MRI for better neck surgery outcomes
This study uses an MRI of the spinal cord to better understand damage from a narrowed neck canal. It helps doctors improve outcomes for people who are about to have neck surgery.
RozzanoAges 18–80 - NCT07678437Enrolling by invitation
Blood flow restriction exercise for strength after spinal cord injury
This trial tests whether controlled exercise with blood flow restriction (a gentle technique) can help you regain strength after an incomplete spinal cord injury. It is for people currently receiving care at Quality Living, Inc.
Omaha, NebraskaAges 19–75 - NCT03364660Recruiting
Epidural stimulation to improve standing and walking after spinal injury
This study tests a nerve-stimulation treatment placed near the spinal cord to help people with long-term, non-worsening spinal cord injuries. It aims to see if stimulation can improve key functions like movement, bladder control, and breathing/standing safety.
Louisville, KentuckyAges 18 years+ - NCT03509571Recruiting
Keto diet to support recovery after spinal cord injury
This trial studies whether a ketogenic (keto) diet can improve movement recovery after spinal cord injury. It may help your body’s healing and brain/spinal cord recovery, but you must meet specific health and safety requirements.
Columbus, OhioAges 19–60 - NCT03736382Recruiting
Study how mild low-oxygen affects sleep apnea and blood pressure
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
Detroit, MichiganAges 18–60 - NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT04047992Recruiting
Training seated balance with the Indego leg device
This study tests whether using the Indego device can improve balance and movement for people with spinal cord injury (SCI). You would practice standing or balance tasks with the device if you meet the safety and fit requirements.
The Bronx, New YorkAges 18 years+ - NCT04721717Recruiting
Workshop for healing writing after paralysis
This trial tests whether a structured writing workshop can help people living with paralysis and their ALS caregivers. It focuses on communication through words (spoken or written) to support well-being.
Birmingham, AlabamaAges 18 years+ - NCT04732065RecruitingPhase 1
ONC206 for certain brain tumors in children and young adults
This Phase 1 study tests ONC206, a new targeted medicine, for diffuse midline gliomas (DMG) with a specific gene change (H3K27 altered) and for some other recurrent brain/spinal cord cancers. It is designed to find the right dose and see whether it can control or shrink tumors after initial treatment or when the cancer returns.
San Francisco, CaliforniaAges 2–21 - NCT04755699RecruitingEarly Phase 1
Electrical stimulation study for hand or limb movement recovery
This early-stage study tests whether regular, skin-based electrical stimulation can help people with paralysis or weakness regain movement. You would attend frequent clinic sessions for months, while the team checks your ability to follow instructions and your safety.
Manhasset, New YorkAges 18–75 - NCT04782947RecruitingPhase 2/Phase 3
Training with back stimulation after traumatic spinal cord injury
This trial studies whether epidural (back-of-spine) stimulation plus guided resistance training can improve strength and function after a traumatic spinal cord injury. It may help people who have an intact nerve pathway below their injury level and can safely use a rehab exoskeleton.
Richmond, VirginiaAges 18–60 - NCT04819737Recruiting
MRI scan study to better detect spinal cord changes in MS
This study tests new MRI scan methods to more clearly find spinal cord lesions in people with multiple sclerosis (MS). It may help improve how MS spinal cord changes are seen on scans.
BaselAges 18 years+ - NCT04936074Recruiting
Fusion vs no fusion after neck cord decompression
This trial compares two surgery approaches for people with a gradually worsening spinal cord problem in the neck: doing fusion (joining bones together) versus not doing fusion after decompression (making more space for the spinal cord). It aims to see which approach works better and is safer for symptoms and recovery.
UppsalaAges 18 years+ - NCT04967274Recruiting
Study testing how the spinal cord controls movement after injury
This trial studies how nerve pathways in the spinal cord help control movements in people with spinal cord injury. It may help researchers better understand movement control and could lead to improved rehab strategies.
ZurichAges 18–80 - NCT05227092Recruiting
MRI scan method test for early spinal lesions in MS
This trial tests a new 3D MRI scan technique to find small, focused spinal cord lesions earlier in people with multiple sclerosis or early MS signs. It may help doctors detect changes sooner, even if lesions are not clearly visible on the first scan.
BordeauxAges 18 years+ - NCT05459207Recruiting
Body fat and pain after spinal cord injury
This study looks at how body composition (amount and distribution of body fat) relates to pain in people with spinal cord injury. It may help researchers understand why pain differs from person to person after spinal cord injury.
Coral Gables, FloridaAges 18–70
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Common questions
- Are there clinical trials for spinal cord diseases?
- Yes. Clin2 currently lists 260 recruiting spinal cord diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal cord diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal cord diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.