Clinical trials
Staphylococcus Aureus clinical trials
Below are recruiting staphylococcus aureus clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06637332RecruitingPhase 4
Comparing two drugs for MRSA bloodstream infections
This trial compares two antibiotics, vancomycin and daptomycin, to see which works better for treating MRSA bacteria in the blood. Patients are randomly assigned to one of the drugs and will be monitored closely for results and side effects.
Blacktown, New South WalesAges 18 years+ - NCT06650501RecruitingPhase 4
Comparing two blood thinners for staph bloodstream infections
This study compares two types of blood thinners (dabigatran vs. a common Xa inhibitor like apixaban) in people with a staph infection in their blood. The goal is to see which is safer and works better.
Montreal, QuebecAges 18 years+ - NCT06650488RecruitingPhase 4
Clopidogrel vs. Aspirin for Heart Protection in Blood Infection Patients
This trial tests whether switching from aspirin to clopidogrel better protects your heart and blood vessels during recovery from a serious staph infection in the blood. You may be eligible if you currently take aspirin for heart or stroke prevention.
Montreal, QuebecAges 18 years+ - NCT04886284RecruitingPhase 2
Cefazolin plus ertapenem for MSSA bloodstream infection
This Phase 2 study tests whether adding ertapenem to cefazolin can improve treatment of staphylococcus (“S. aureus”) bloodstream infection that is likely methicillin-susceptible (MSSA). It aims to start the right antibiotics quickly, before MRSA status is fully confirmed, using early testing and a treatment plan guided by infectious-disease specialists.
Calgary, AlbertaAges 18–100 - NCT06726395RecruitingPhase 4
Comparing two antibiotics for staph bloodstream infection
This trial compares two antibiotics, cloxacillin and benzylpenicillin, to see which works better for patients with a bloodstream infection caused by a specific type of staph bacteria that responds well to penicillin. It may help guide more effective treatment.
LundAges 18 years+ - NCT07376889RecruitingPhase 4
Combination antibiotics for blood staph infection
This study tests different combinations of antibiotics to treat a staph infection in the blood. If you're in an Intermountain hospital with this infection, the trial may help doctors find the most effective treatment for you.
Brighton, ColoradoAges 18 years+ - NCT06336824RecruitingPhase 3
Switching from IV to oral antibiotics for staph bloodstream infection
This trial tests whether switching from IV antibiotics to oral antibiotics after 3–7 days is safe and effective for people with uncomplicated Staphylococcus aureus bloodstream infections. It may help you avoid a longer hospital stay and reduce IV-related complications.
Johor Bahru, JohorAges 18 years+ - NCT05117398RecruitingPhase 3
Dalbavancin vs standard antibiotics for catheter bloodstream infection
This trial tests whether dalbavancin (an antibiotic given as a dose or doses) works as well as standard antibiotics to treat bloodstream infections related to a removed IV catheter caused by Staphylococcus aureus. It may help reduce treatment time and dosing complexity if you qualify.
GarchesAges 18 years+ - NCT05137119RecruitingPhase 4
Adaptive study of treatments for staph bloodstream infection
This trial tests the best treatment approach for bloodstream infections caused by Staphylococcus aureus (“S. aureus”). It uses a flexible design to decide which treatment track you fit into, and may help improve recovery while avoiding unnecessary medications.
Houston, TexasAges Any age - NCT05655091RecruitingPhase 2
Personalized IV antibiotics for serious Staph aureus infections
This Phase 2 study tests whether continuous IV antibiotics plus “drug level monitoring” (TDM) works better than the usual treatment for complicated Staph aureus infections. It may help ensure the antibiotic dose stays in an effective range while you’re being treated.
BaselAges 18 years+ - NCT07148960Enrolling by invitationPhase 4
Does early dual therapy improve outcomes for staph bloodstream infections?
This study looks at whether giving two antibiotics early for a serious staph infection in the blood leads to better results than the standard one antibiotic. It uses existing hospital monitoring and follow-up visits to track progress.
Morgantown, West VirginiaAges 18 years+ - NCT06574399Recruiting
Staph blood infection study: understanding severity
This study looks at different types of Staph aureus blood infections to understand which ones are more likely to cause severe illness or death. It may help doctors predict who needs more aggressive treatment.
SevilleAges 18 years+ - NCT07253688RecruitingPhase 3
Rifampin for staph infections on artificial heart valves
This trial tests adding the antibiotic rifampin to standard treatment for staph infections on prosthetic heart valves. It aims to see if this combination improves outcomes.
Montreal, QuebecAges 18 years+ - NCT06594250Recruiting
Nasal staph bacteria in patients with staph bloodstream infection
This trial studies the bacteria living in the nose of patients with a staph bloodstream infection. It aims to better understand why some infections persist, which could lead to better treatments.
Saint-EtienneAges 18 years+ - NCT06457386Recruiting
Echocardiogram vs no echocardiogram for low-risk Staph blood infection
This study compares two approaches for people with a blood infection caused by Staphylococcus aureus who are at low risk for heart infection (VIRSTA score <3). Half of the participants will get a standard echocardiogram (heart ultrasound), and the other half will not, to see if skipping the test is safe and effective.
ParisAges 18 years+ - NCT06378359Recruiting
Preventing staph infections with pre-surgery decolonization
This trial tests if a simple at-home treatment (using a nasal ointment and special body wash) before surgery can prevent staph infections at the surgical site. It's for adults having outpatient surgery in several specialties, like orthopedics or general surgery.
Minneapolis, MinnesotaAges 18 years+ - NCT06872099Recruiting
MRSA in hospital children: studying antibiotics and nose bacteria
This study looks at how antibiotics affect MRSA (a type of staph infection) in the noses of hospitalized children. It may help doctors better understand MRSA to improve treatment.
Pavia, PaviaAges 1–16 - NCT05094570RecruitingPhase 4
Dupilumab for nasal polyps with staph bacteria
This trial studies whether dupilumab (an injection) can reduce staph bacteria in the nose and make the nose’s microbes more diverse in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). If you already have a plan to start dupilumab as standard care, the study may help doctors better understand why it works.
Charlottesville, VirginiaAges 18–65 - NCT06749457RecruitingPhase 1/Phase 2
Study of a new drug for healthy adults and kidney patients on dialysis
This trial tests a new drug called AZD7760 in two groups: healthy adults (Phase I) and adults with end-stage kidney disease who are on hemodialysis through a central venous catheter (Phase IIa). The goal is to see how safe the drug is and how the body processes it. This could lead to a new treatment option for people on dialysis.
Huntsville, AlabamaAges 18–55 - NCT06168474Recruiting
Simplified consent process for staph infection trial
This study tests a simpler way to explain the trial and get your consent. If you have a staph bloodstream infection, you may be able to join and help improve how consent is done for future patients.
Calgary, AlbertaAges Any age - NCT07612813RecruitingPhase 1
Safety study of AZD7760 in healthy Japanese adults
This is a Phase 1 safety study of a new investigational drug called AZD7760 in healthy Japanese volunteers. The trial will test how the body handles the drug and monitor for any side effects.
Sumida-kuAges 18–55 - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT05899140RecruitingPhase 4
Clindamycin added to treat certain skin infections
This trial tests whether adding clindamycin helps treat skin and soft-tissue infections caused by Staphylococcus aureus. You may be eligible if your infection was diagnosed recently and a sample was collected soon after hospital admission.
MasokoriAges 18 years+ - NCT06283355RecruitingPhase 1
Comparing one vs. multiple nasal treatments in NICU babies
This study tests whether giving one versus multiple doses of a special nasal treatment (called nasal microbiota therapy, or NMT) changes the types of helpful bacteria in your baby's nose. The goal is to see if the treatment keeps bad bacteria, like staph, from growing.
Baltimore, MarylandAges birth–60 years
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Common questions
- Are there clinical trials for staphylococcus aureus?
- Yes. Clin2 currently lists 27 recruiting staphylococcus aureus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a staphylococcus aureus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a staphylococcus aureus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.