Clinical trials
Stenosis clinical trials
Below are recruiting stenosis clinical trials, each written for real people, not researchers. We’re tracking 495 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06991517Recruiting
TAVR sizing study for bicuspid aortic valve patients
This study tests a special sizing method (ABC algorithm) to help doctors select the right valve for people with a bicuspid aortic valve. It aims to improve outcomes for those getting a Sapien 3 valve through a catheter (TAVR).
St Leonards, New South WalesAges Any age - NCT06964035Enrolling by invitation
How original valve problem affects new valve's long-term health
This study looks at how the original problem with your aortic valve (narrowing, leaking, or both) might affect how long the replacement valve stays healthy. If you had both your aortic and mitral valves replaced, doctors want to track how well the new valve works over time.
Maastricht, MaastrichtAges 18 years+ - NCT06953206Recruiting
Long-term study of a new heart valve for aortic stenosis
This study is testing a new heart valve called the SAPIEN 3 Ultra RESILIA valve for people with severe aortic stenosis. Researchers want to see how well it works and how safe it is over 10 years after a minimally invasive valve replacement procedure called TAVI.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT06924151Recruiting
Surgery for Aortic Valve in Low Risk Patients
This trial tests if surgery to replace your aortic valve is safe and effective for people with severe aortic stenosis who are at low risk for complications. It compares surgery to another procedure to see which works best.
Matsudo, ChibaAges Any age - NCT06924593Recruiting
Shunt for carotid artery narrowing
This study tests a new device that is placed through the carotid artery in the neck to temporarily block blood flow during a procedure to open up a narrowed carotid artery. It might be an option for people who have high-risk features that make traditional surgery more challenging.
BeijingAges 18 years+ - NCT06925282Recruiting
Breathing help during airway surgery
This study looks at what factors make some patients need extra breathing support during airway surgery when using a special oxygen delivery method called THRIVE. The goal is to better understand who might need additional help to keep their oxygen levels safe.
SeoulAges 18 years+ - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT06911463Enrolling by invitation
Pain relief for TAVI valve procedure
This study tests two numbing injections for people having a new aortic valve placed through a leg artery (TAVI). One injection is near the hip bone, the other in the groin area. The goal is to see which one provides better pain control while keeping you awake and comfortable.
CairoAges 20 years+ - NCT06902740RecruitingPhase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing
This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06891079Enrolling by invitation
Guiding TAVI with a new angiographic method
This study tests a new way to use X-ray images during a TAVI procedure to check how well the new valve is working right away. It may help doctors make real-time adjustments to improve the outcome.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04861805Recruiting
Transcatheter aortic valve replacement study for high-risk seniors
This study tests a self-expanding artificial aortic valve placed through a blood vessel (no open-heart surgery) in older adults with severe aortic valve narrowing. It may help improve symptoms and heart function by treating the blocked valve.
Bahía BlancaAges 65 years+ - NCT06754956Recruiting
MRI Study of Artery Plaques Using Different MRI Scanners
This study investigates the build-up of fatty deposits called plaques in arteries of the brain and neck using two different strengths of MRI scanners. It aims to understand how well these MRI techniques can image the plaques, which could help doctors better diagnose and manage stroke risk.
ShanghaiAges 18–95 - NCT06875154Enrolling by invitation
How original tricuspid valve disease affects new valve lifespan
This study looks at how the type of tricuspid valve problem you had originally (narrowing, leaking, or both) might affect how long a replacement valve lasts. If you have had only tricuspid valve replacement surgery, this trial could help doctors understand your long-term outcome better.
MaastrichtAges 18 years+ - NCT06861361Recruiting
Surgery versus transcatheter valve replacement in younger patients
This trial compares two ways to replace a narrowed aortic heart valve in patients aged 65 to 75. It aims to find which approach—surgical valve replacement or a catheter-based procedure—works better for people in this age group.
GrazAges 65–75 - NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06828770Recruiting
Minima stent system long-term safety study
This study checks the safety of the Minima Stent System over time. It is for people who need a stent to keep their blood vessel open. The study wants to see how the device works in real-world use.
Los Angeles, CaliforniaAges Any age - NCT06830499Recruiting
Sapien 3 valve for younger Chinese patients with severe aortic stenosis
This trial tests a newer artificial heart valve (Sapien 3) placed through a small tube in the leg, for younger people (50–70) with severe aortic stenosis. It aims to see if this less invasive option works well in this age group.
Xi'an, ShaanxiAges 50–70 - NCT06833762Recruiting
Predicting improvement after TAVI using exercise tests
This trial looks at whether a simple exercise test (called CPET) can help predict how much your heart function will improve after TAVI, a procedure to replace a narrowed heart valve. If you're scheduled for TAVI through your leg artery and are 18 or older, you might be able to join.
BarcelonaAges 18 years+ - NCT06816485Recruiting
New balloon safety in TAVI for severe aortic stenosis
This trial studies a new balloon used during a TAVI procedure to replace your aortic valve without open-heart surgery. It aims to see if the balloon is safe and works well for people with severe aortic stenosis.
BarcelonaAges 18 years+ - NCT06822400Recruiting
Study of Tetralogy of Fallot in Newborns
This trial looks at newborns with Tetralogy of Fallot, a heart condition present at birth. It aims to study the best way to treat these babies in the first month of life.
Beijing, Beijing MunicipalityAges 1 minute–6 months - NCT06818435Recruiting
Registry study of the Myval heart valve for severe aortic stenosis
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
CarnaxideAges 18 years+ - NCT06807099Recruiting
Stent graft for dialysis access problems
This trial tests a special stent graft called WRAPSODY CIE to treat narrowed or blocked veins in the arm used for dialysis. It aims to keep your access working well so you can continue receiving hemodialysis.
Dothan, AlabamaAges 18 years+ - NCT06777368Recruiting
Redo TAVR for failed transcatheter aortic valves
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
Birmingham, AlabamaAges 18–105 - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90
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Common questions
- Are there clinical trials for stenosis?
- Yes. Clin2 currently lists 495 recruiting stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.