Clinical trials
Stenosis clinical trials
Below are recruiting stenosis clinical trials, each written for real people, not researchers. We’re tracking 495 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Gilbert, ArizonaAges 18 years+ - NCT04392206RecruitingPhase 1
Study paste to prevent narrowing in new arm dialysis fistulas
This Phase 1 study tests a treatment (called AMSCs) to help stop scar-like narrowing at the connection point of a new arm dialysis fistula. If it works and is safe, it could improve long-term fistula function so dialysis can work better.
Jacksonville, FloridaAges 18–85 - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT04275726Recruiting
Myval heart valve study for adults needing TAVI
This trial studies whether the Myval THV (a new heart valve) is safe and effective for adults who need TAVI, a procedure to replace a narrowed heart valve without open-heart surgery. You may be considered if a heart team says you’re a good candidate for this valve procedure and you’re willing to join the study.
MinskAges 18 years+ - NCT04261478Recruiting
Treatment for stroke caused by blocked brain and neck arteries
This trial studies a procedure that opens blocked blood vessels in and behind the brain during a stroke, sometimes after standard clot-thinning medicine. It may help people who have brain tissue that can still be saved and a major blockage in both the neck and brain arteries.
Montreal, QuebecAges 18 years+ - NCT04234841Recruiting
Study of outcomes after aortic valve replacement
This study follows adults who are having aortic valve replacement (through surgery or a catheter) to see how often certain outcomes happen after the procedure. You may be asked for blood tests and scans at set times, and some people may also be offered a special CT scan.
Stevenage, HertforshireAges 18 years+ - NCT04240119Enrolling by invitation
Study blood vessel growth markers in certain brain artery narrowing
This study looks at “angiogenic markers,” which are blood measures that may reflect how blood vessels grow, in people with significant narrowing of a brain artery. It aims to better understand these changes and how they relate to cerebrovascular disease.
Ages 18 years+ - NCT03728049Recruiting
Blood test during TAVI to improve heart valve procedure outcomes
This study checks whether a quick bedside blood test helps guide care during a minimally invasive TAVI procedure (a new valve put in without open-heart surgery). It may improve safety and outcomes by helping the team manage bleeding-related decisions in real time.
Clermont-FerrandAges 18 years+ - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT03628313Recruiting
Aortic Valve Narrowing: Long-term Outcomes Study
This study follows patients with aortic stenosis (a narrowing of the heart valve that controls blood flow from the heart) to understand how the condition progresses over time and what outcomes patients experience. By reviewing medical records and contacting patients for follow-up, researchers hope to better predict who is at higher risk and inform treatment decisions.
Amiens, FranceAges 18–100 - NCT03588481Recruiting
Check DeSyne X2 coronary stent in a heart registry
This study adds people to a registry to track outcomes after getting a specific heart stent called DeSyne X2. It may help doctors understand how well this stent works and how it affects recovery over time.
IncheonAges 19 years+ - NCT03303612Recruiting
Check monitoring vs guided pacing after valve replacement
This study compares two ways to decide when someone needs a pacemaker after they get a new heart valve (TAVI) and develop a new, persistent left bundle branch block (LBBB). It may help reduce unnecessary procedures while still keeping heart rhythms safe.
Edmonton, AlbertaAges 18 years+ - NCT03072927Recruiting
Study of Medicare patients after mild back decompression
This study uses Medicare records to look at outcomes for people who receive MILD or an interspinous process decompression procedure for lumbar spinal stenosis with nerve symptoms. It may help confirm how well these less-invasive procedures work in real-world patients.
Athens, AlabamaAges 18 years+ - NCT02748941Recruiting
Imaging study of narrowed neck arteries after stroke
This study looks at new imaging markers in people with significant narrowing of the carotid artery (the main artery in the neck). It compares people who recently had a stroke from that artery with people who have no recent stroke, to better understand stroke risk and artery disease.
BronAges 18 years+
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Common questions
- Are there clinical trials for stenosis?
- Yes. Clin2 currently lists 495 recruiting stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.