Clinical trials
Stenosis clinical trials
Below are recruiting stenosis clinical trials, each written for real people, not researchers. We’re tracking 495 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06898086Enrolling by invitation
TAVI with or without heart artery check for severe aortic stenosis
This trial compares two approaches for replacing a tight aortic heart valve (TAVI) through a leg artery: doing it with or without a routine check of your heart's arteries (coronary angiogram). If you have severe aortic stenosis and are scheduled for TAVI, this study helps find out whether skipping the artery check is safe and effective.
GrazAges 18 years+ - NCT06886802Recruiting
Study of a new neck surgery for spinal stenosis
This study is looking at a new, less invasive neck surgery for people with cervical spinal stenosis (narrowing of the spinal canal in the neck). It tests whether this surgery helps relieve symptoms like pain, numbness, or weakness in the arms or legs.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT06863883Recruiting
Aortic stenosis study: looking at outcomes after TAVI
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
GothenburgAges Any age - NCT06859255Recruiting
Comparing heart valves for small aortic openings
This trial compares different types of heart valves (surgical and less-invasive) used in people with a small heart valve opening. It aims to see which valves work best, and will follow up with patients who already had the procedure.
Bari, ApuliaAges Any age - NCT05002751Recruiting
Measuring how radiation affects vaginal narrowing in cervical cancer
This study measures how radiation therapy changes the vagina’s flexibility and shape in people with newly diagnosed, advanced cervical cancer that has spread to nearby lymph nodes. The goal is to better understand what happens over time, which may help guide prevention and treatment of vaginal narrowing.
La Jolla, CaliforniaAges 18–99 - NCT06448949Recruiting
Blood flow study after flow diverter for brain aneurysm
This study uses detailed 3D X-rays and ultrasound to understand how blood flows through a mesh tube (flow diverter) placed in a brain aneurysm. It may help doctors predict and prevent narrowing inside the tube.
Guangzhou, GuangdongAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Huntsville, AlabamaAges Any age - NCT06761170RecruitingPhase 2
Spray Freezing for Non-Cancerous Airway Narrowing
This trial is testing a treatment called spray cryotherapy, which uses extreme cold to open up a narrowed airway. It may help people with non-cancerous (benign) narrowing of the windpipe or voice box area that is causing symptoms like trouble breathing.
Boston, MassachusettsAges Any age - NCT06749145Enrolling by invitation
Using deep learning to find aortic stenosis earlier
This study tests if a deep learning tool can help detect aortic stenosis, a heart valve condition, in older adults during routine primary care visits. If you are 70 or older and have not had a recent echocardiogram, you may be able to join.
New Haven, ConnecticutAges 70 years+ - NCT06749132Enrolling by invitation
AI-powered monitoring for mild aortic valve disease
This study uses an artificial intelligence (AI) program to analyze past heart ultrasound images and predict if your aortic valve condition (mild thickening or narrowing) may get worse over time. The goal is to catch changes early and personalize your follow-up care.
New Haven, ConnecticutAges 65 years+ - NCT06713889Recruiting
Study of heart valve disease and events
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
LyonAges 18 years+ - NCT06679517Enrolling by invitation
Long-term follow-up for severe aortic stenosis patients considered for TAVI
This study follows patients with severe aortic stenosis (a heart valve condition) who are being evaluated for a keyhole procedure called TAVI. It aims to understand their long-term outcomes after the standard evaluation process.
FerraraAges 18 years+ - NCT06638268Recruiting
TAVI for severe aortic stenosis in cardiogenic shock
This study tests whether a procedure called TAVI (a valve replacement done through a tube in the leg) can help people with severe aortic stenosis who are in cardiogenic shock, a dangerous condition where the heart can't pump enough blood. The goal is to see if urgent valve replacement improves survival.
Copenhagen OAges Any age - NCT06597188Enrolling by invitation
TAVR vs. Surgery for severe bicuspid aortic valve stenosis
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
Chengdu, SichuanAges 18–75 - NCT06589063Recruiting
TAVR for severe low flow, low gradient aortic stenosis
This study tests whether TAVR (a minimally invasive valve replacement) helps people with a specific type of severe aortic stenosis where the heart doesn't pump as strongly. It aims to see if the procedure improves symptoms and outcomes.
SalernoAges 18 years+ - NCT06596460Recruiting
Imaging study after TAVI valve replacement
This study collects extra imaging data from 40 people who are already scheduled for a routine TAVI procedure to replace a narrowed aortic heart valve. The goal is to better understand the valve's structure and function using scans.
London, EnglandAges 18 years+ - NCT06580158Recruiting
AI for diagnosing heart valve and pump problems
This trial is testing how well an AI tool can help doctors diagnose aortic stenosis and diastolic dysfunction by analyzing your scheduled ECG (heart test). The study takes place during your routine care at the clinic.
Rochester, MinnesotaAges 60 years+ - NCT06571175Enrolling by invitation
Measuring heart scarring in aortic stenosis patients
This study uses imaging to measure heart scarring in people with aortic stenosis, a condition where the heart valve is narrowed. It aims to better understand how scarring affects long-term outcomes.
Trondheim, TrøndelagAges 18–90 - NCT06452173Enrolling by invitation
Risk prediction for stroke in carotid artery narrowing
This study uses MRI scans to build a risk prediction model for stroke and other cerebrovascular events in people with carotid artery stenosis (narrowing of the neck arteries). By participating, you help doctors better understand who is at highest risk, which may lead to more personalized treatment.
Beijing, Beijing MunicipalityAges Any age - NCT05511792Recruiting
Smaller valve size approach versus standard valve size in TAVR
This trial compares a “smaller valve sizing” approach versus the usual sizing method during TAVR (a catheter-based valve replacement) for people with bicuspid aortic stenosis. The study aims to see which method improves safety and outcomes for the right valve fit.
Fuzhou, FujianAges 60 years+ - NCT06171737Enrolling by invitation
Shared decision-making for severe aortic stenosis
This study tests a way to help people with severe aortic stenosis make informed choices about treatment. It may help you talk with your heart team about options like valve replacement.
San Francisco, CaliforniaAges 65–85 - NCT06089746Recruiting
Posture therapy for older veterans with spinal stenosis
This trial tests a non-invasive posture therapy for older veterans with lumbar spinal stenosis (a narrowing in the lower spine). It aims to reduce pain and improve walking without surgery.
Baltimore, MarylandAges 55–80 - NCT06096142Recruiting
A drug-coated stent for dialysis access narrowing
This trial tests a new covered stent that slowly releases a drug to keep the dialysis access (a surgically created blood vessel) open. It is designed for people whose access is narrowed or blocked and needs a procedure to restore blood flow and allow dialysis to continue.
Salvador, Estado de BahiaAges 18 years+ - NCT06085209RecruitingPhase 1
Cold spray treatment for non-cancerous airway narrowing
This trial tests a freezing spray (cryospray) to treat narrowing of the windpipe (trachea) that is not caused by cancer. It may be an option if you need a procedure to open your airway.
Richmond, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for stenosis?
- Yes. Clin2 currently lists 495 recruiting stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.