Clinical trials · Boston, MA
Stroke clinical trials in Boston
We’re tracking 46 recruiting stroke studies with a site in or near Boston — including Early Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT07172464Recruiting
Study of a new device to close a hole in the heart after a stroke
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
Boston, MassachusettsAges 18–65 - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Boston, MassachusettsAges 18 years+ - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Boston, MassachusettsAges 18 years+ - NCT07091851Recruiting
Blood pressure support group for stroke survivors
This study tests whether a group-based program can help people with high blood pressure and a recent mild to moderate stroke better manage their blood pressure. You'll work with a team and use online tools to keep your blood pressure in a healthy range.
Boston, MassachusettsAges 35 years+ - NCT07414732Recruiting
Testing a new approach to help stroke survivors take blood pressure pills
This trial tests a simple program to help people who have had a stroke stick with their blood pressure medication. It uses text messages and a medication organizer to make it easier to remember pills and keep blood pressure under control.
Boston, MassachusettsAges 18–99 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Boston, MassachusettsAges 18 years+ - NCT07739875Recruiting
App-based therapy for post-stroke word-finding
This trial tests a therapy delivered through a smartphone app to help people with aphasia (trouble finding words after a stroke) improve their ability to name things. The therapy happens in daily life, not in a clinic, and is personalized to the words you need most.
Boston, MassachusettsAges 18–89 - NCT06511934Recruiting
BrainGate2 tablet trial for tetraplegia
This trial tests a brain-computer interface (BrainGate2) system for people with tetraplegia (paralysis of all four limbs). It aims to see if the system can help you control a tablet computer using only your brain signals. This is for people who were already in the BrainGate2 study.
Boston, MassachusettsAges 18–80 - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Boston, MassachusettsAges 18–80 - NCT06982339Recruiting
Beat the Heat Boston study
This study provides free air conditioning units to older adults in certain Boston neighborhoods who don't have AC. It aims to see if cooling homes can help with heat-related health risks for people with certain chronic conditions.
Boston, MassachusettsAges 55–95 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Boston, MassachusettsAges 1–120 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Boston, MassachusettsAges 18 years+ - NCT04851886Recruiting
Vision tool to guide robot therapy for stroke arm posture
This trial tests a vision-based system that detects your arm and posture during robot-assisted upper-arm therapy after a prior stroke. It may help the robot guide treatment more safely and accurately based on your movements and positioning.
Charlestown, MassachusettsAges 18–80 - NCT06787729Recruiting
Using sensors and a smartphone to help arm recovery after stroke
This study tests if wearing small sensors on your arm at home and using a smartphone app can help improve how you use your weaker arm after a stroke. It is designed for people who are at least a year past their stroke and want to take an active role in their recovery.
Charlestown, MassachusettsAges 18–80 - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80 - NCT05832567Recruiting
Study of hidden and open placebo effects in stroke recovery
This study looks at how “open” (told) and “hidden” (not told) placebo effects may change arm recovery after a long-term stroke. You would do recovery-related assessments and likely receive brain-stimulation or related procedures to test these effects.
Cambridge, MassachusettsAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Burlington, MassachusettsAges 18 years+ - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Worcester, MassachusettsAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Worcester, MassachusettsAges 18–90 - NCT05993221Recruiting
Understanding arm weakness after stroke
This study looks at the brain changes that happen after a stroke and how they affect arm movement. It uses MRI scans and gentle magnetic pulses to understand your brain better, which may help guide future treatments.
Providence, Rhode IslandAges 18–90 - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Providence, Rhode IslandAges 18–70 - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Providence, Rhode IslandAges 18–85
Hear when a new Stroke trial opens near Boston, MA
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Stroke trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting stroke studies listed above.
- Massachusetts General Hospital · 7 studies
- Spaulding Rehabilitation Hospital · 3 studies
- Boston Medical Center · 2 studies
- Rhode Island Hospital · 2 studies
- Beth Israel Deaconess Medical Center
- Brigham and Women's Hospital
- Decentralized
- Harvard TH Chan School of Public Health
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Massachusetts.
Common questions
- Are there stroke clinical trials near Boston?
- Yes. We're currently tracking 46 recruiting stroke studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.