Clinical trials · Boston, MA
Stroke clinical trials in Boston
We’re tracking 48 recruiting stroke studies with a site in or near Boston — including Early Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06511934Recruiting
BrainGate2 tablet trial for tetraplegia
This trial tests a brain-computer interface (BrainGate2) system for people with tetraplegia (paralysis of all four limbs). It aims to see if the system can help you control a tablet computer using only your brain signals. This is for people who were already in the BrainGate2 study.
Boston, MassachusettsAges 18–80 - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Boston, MassachusettsAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Boston, MassachusettsAges 22–75 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Boston, MassachusettsAges 18–79 - NCT03485040Recruiting
Rehab study for arm weakness after stroke
This study tests a rehabilitation approach to help people recover arm movement after an ischemic or bleeding stroke. You may be able to join if you’re currently an inpatient in the stroke neurology unit and have arm weakness but are medically stable and able to follow simple instructions.
Boston, MassachusettsAges 18–90 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Boston, MassachusettsAges 18 years+ - NCT06998485Recruiting
Arm recovery after a first stroke
This study tests an intensive 6-week arm training program for people who had a first stroke 3 to 6 months ago and still have arm weakness. The goal is to see how the brain can recover arm function.
Boston, MassachusettsAges 18 years+ - NCT07172464Recruiting
Study of a new device to close a hole in the heart after a stroke
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
Boston, MassachusettsAges 18–65 - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Boston, MassachusettsAges 18 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Boston, MassachusettsAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Boston, MassachusettsAges 22–85 - NCT02896348Recruiting
Home therapy training for hand function after stroke
This trial tests a physio-and-neuro “platform” to help retrain hand movement at home in people who are at least 6 months out from a stroke. It may help improve hand function and confidence doing daily tasks using an at-home retraining program.
Boston, MassachusettsAges 21–80 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Boston, MassachusettsAges 18 years+ - NCT04187131Recruiting
AR brain tests and rehab for stroke neglect
This trial tests an augmented reality (AR) system to find and treat “neglect” after an acute stroke. If you qualify, it may help assess attention problems and guide rehabilitation exercises.
Boston, MassachusettsAges 18 years+ - NCT06787729Recruiting
Using sensors and a smartphone to help arm recovery after stroke
This study tests if wearing small sensors on your arm at home and using a smartphone app can help improve how you use your weaker arm after a stroke. It is designed for people who are at least a year past their stroke and want to take an active role in their recovery.
Charlestown, MassachusettsAges 18–80 - NCT04851886Recruiting
Vision tool to guide robot therapy for stroke arm posture
This trial tests a vision-based system that detects your arm and posture during robot-assisted upper-arm therapy after a prior stroke. It may help the robot guide treatment more safely and accurately based on your movements and positioning.
Charlestown, MassachusettsAges 18–80 - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80 - NCT05832567Recruiting
Study of hidden and open placebo effects in stroke recovery
This study looks at how “open” (told) and “hidden” (not told) placebo effects may change arm recovery after a long-term stroke. You would do recovery-related assessments and likely receive brain-stimulation or related procedures to test these effects.
Cambridge, MassachusettsAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Burlington, MassachusettsAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Worcester, MassachusettsAges 18–90 - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Worcester, MassachusettsAges 18 years+ - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Providence, Rhode IslandAges 18–85 - NCT05993221Recruiting
Understanding arm weakness after stroke
This study looks at the brain changes that happen after a stroke and how they affect arm movement. It uses MRI scans and gentle magnetic pulses to understand your brain better, which may help guide future treatments.
Providence, Rhode IslandAges 18–90 - NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Providence, Rhode IslandAges 18–70
Hear when a new Stroke trial opens near Boston, MA
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Stroke trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting stroke studies listed above.
- Massachusetts General Hospital · 6 studies
- Boston Medical Center · 5 studies
- Spaulding Rehabilitation Hospital · 5 studies
- Rhode Island Hospital · 4 studies
- University of Massachusetts Chan Medical School · 3 studies
- Brigham and Women's Hospital · 2 studies
- Boston University Medical Center
- Decentralized
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Massachusetts.
Common questions
- Are there stroke clinical trials near Boston?
- Yes. We're currently tracking 48 recruiting stroke studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.