Clinical trials · Cleveland, OH
Stroke clinical trials in Cleveland
We’re tracking 20 recruiting stroke studies with a site in or near Cleveland — including Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Cleveland
- NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Cleveland, OhioAges 18 years+ - NCT07738978Recruiting
Movement and health study for paralysis
This study is looking at ways to improve movement and health for people with paralysis from conditions like spinal cord injury, stroke, traumatic brain injury, or multiple sclerosis. It involves exercises and may include electrical stimulation to help your leg and trunk muscles work better.
Cleveland, OhioAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Cleveland, OhioAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Cleveland, OhioAges 18–80 - NCT06451757RecruitingPhase 3
A trial of sonlicromanol for mitochondrial disease
This trial tests a new medicine, sonlicromanol, for people with a specific type of mitochondrial disease (caused by the m.3243A>G mutation) who also have chronic fatigue and muscle weakness. The goal is to see if it helps improve symptoms and daily function.
Cleveland, OhioAges 18 years+ - NCT06585943Recruiting
Cycling therapy for stroke recovery
This study tests a special cycling exercise program designed to help people who have had a stroke regain arm and leg movement. It aims to see if this focused cycling therapy can improve recovery and reduce healthcare costs.
Cleveland, OhioAges 18–85 - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Cleveland, OhioAges 60 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Cleveland, OhioAges 18 years+ - NCT05983185Recruiting
Prism adaptation therapy for right brain stroke recovery
This study tests whether prism adaptation therapy (wearing special glasses that shift how you see) can help improve attention and function after a right-brain stroke. You may be eligible if you recently had a first right-brain stroke and can sit up to take part in the therapy.
Cleveland, OhioAges 18 years+ - NCT07768761Recruiting
Electrical stimulation exercise for lower limb paralysis
This trial tests whether a muscle exercise program using electrical stimulation can help people with paralysis in their legs. It may improve muscle strength, blood flow, or other health benefits.
Cleveland, OhioAges 18 years+ - NCT05866003Recruiting
Brain stimulation plus hand training after stroke
This trial tests whether a combination of brain stimulation and structured hand practice can improve hand movement for people recovering from stroke. It may help because the training targets upper-limb function while using therapy intended to support recovery.
Cleveland, OhioAges 21–90 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Cleveland, OhioAges 18 years+ - NCT00623389Recruiting
Testing a leg neuroprosthesis for walking and leg control
This trial tests an advanced device that helps control and use your legs and trunk muscles for movement. It may help people with certain types of paralysis or weakness to improve function, while closely monitoring safety and comfort.
Cleveland, OhioAges 21–75 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Cleveland, OhioAges 18 years+ - NCT06402968Recruiting
Clevidipine for treating high blood pressure after a brain bleed
This trial tests a blood pressure medicine called clevidipine given through an IV to people with a brain bleed (intracerebral hemorrhage). The goal is to see if quickly lowering blood pressure helps prevent more bleeding and improve recovery.
Cleveland, OhioAges 18–100 - NCT03870672Recruiting
Brain stimulation plus hand practice for severe stroke arm weakness
This trial tests whether using noninvasive brain stimulation, along with guided hand exercises, can improve hand opening and arm function after a stroke. It may help people with severe hand weakness who still have some ability to follow instructions and move the shoulder and elbow.
Cleveland, OhioAges 18–90 - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT05296408Recruiting
Arm exoskeleton rehab for chronic stroke weakness
This trial tests a wearable arm exoskeleton that uses your muscle signals to help rehab a weak arm after stroke. It may help improve arm movement by pairing training with this device, but you must meet specific movement, skin, and scan-safety requirements.
Cleveland, OhioAges 18–89 - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Cleveland, OhioAges 21 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Akron, OhioAges 18–90
Hear when a new Stroke trial opens near Cleveland, OH
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Stroke trials in other cities
Where these studies are running near Cleveland
Institutions with a site for the recruiting stroke studies listed above.
- Cleveland Clinic · 11 studies
- Louis Stokes Cleveland VA Medical Center · 5 studies
- MetroHealth Medical Center · 5 studies
- University Hospitals Cleveland Medical Center · 4 studies
- Cleveland Clinic Akron General · 3 studies
- Summa Health System - Akron Campus
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Ohio.
Common questions
- Are there stroke clinical trials near Cleveland?
- Yes. We're currently tracking 20 recruiting stroke studies with a site near Cleveland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Cleveland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Cleveland to take part?
- Not necessarily. These studies have a site near Cleveland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Cleveland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.