Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04076735Recruiting
Compare fixing vs replacing certain leg bone fractures in seniors
This trial studies which operation works better for an acute distal femur (upper knee area) fracture in older adults: repairing/fixing it versus replacing the joint/bone. It may help find the safest approach and improve walking and recovery for people in this situation.
Toronto, OntarioAges 65 years+ - NCT04133077Recruiting
Biobank study using tumor tissue to grow patient tumor models
This study takes small samples of your breast tumor tissue after (or during) treatment and grows them in lab animals to better study breast cancer. It may help researchers test future ideas for treating aggressive breast cancer types like triple-negative or Luminal B.
Clermont-Ferrand, Puy-de-DômeAges 18 years+ - NCT04130464RecruitingPhase 4
Analgesic placed inside the belly for after-surgery pain
This study tests whether placing a pain medicine inside the abdomen during hysterectomy can reduce postoperative pain. It targets people having specific types of minimally invasive hysterectomy for non-cancer reasons.
Washington D.C., District of ColumbiaAges 18–65 - NCT03930810Enrolling by invitation
Study of PFIC types and how bile diversion affects outlook
This study looks at different genetic liver conditions called PFIC and follows how they progress over time. It also studies whether a procedure called biliary diversion may improve symptoms or long-term outcomes.
Groningen, Provincie GroningenAges birth–65 years - NCT04014647Recruiting
Blood test to predict heart risk during planned surgery
This trial checks a blood test called NT-proBNP (a marker related to heart stress) to help predict outcomes after planned surgery. It may help doctors identify which patients are at higher risk so they can tailor monitoring and care.
Norwich, NorfolkAges 18 years+ - NCT03952299RecruitingPhase 3
Oxybutynin patch after bladder surgery for children’s urgency pain
This study tests whether an oxybutynin skin patch after bladder surgery can reduce bladder pain and urgent, frequent urination in children. It compares symptoms after surgery to see if the patch helps more than the control plan.
Sacramento, CaliforniaAges 4–8 - NCT03722537Recruiting
Test of cartilage graft surgery for thumb arthritis pain
This trial looks at using a donated cartilage-and-bone graft during surgery for thumb “basal joint” arthritis. It may help reduce pain and improve thumb function if you are planning surgery for this condition.
New York, New YorkAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT03632200Recruiting
Nutrition care plan after head and neck cancer surgery
This study tests a structured nutrition care plan for people after head and neck cancer surgery. It may help you maintain weight and nutrition during recovery so you can heal better.
AmiensAges 18–80 - NCT03567213Recruiting
CortiCom brain signal system for communication in severe paralysis
This trial tests a system that records brain signals to help people with severe paralysis and little or no speech communicate. It involves a surgical implant and frequent study visits to see if the system can work safely and reliably for communication.
Baltimore, MarylandAges 22–70 - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+ - NCT03446287Recruiting
Surgery outcomes study for complex abdominal and chest aneurysms
This study follows people with complex aortic aneurysms who need open surgery instead of a less invasive procedure. It aims to understand treatment results and may help improve care for similar patients.
Rochester, MinnesotaAges 18 years+ - NCT03451968Recruiting
Amino acid levels in long ICU stays after surgery or trauma
This study measures amino acids (building blocks from food) in people who are critically ill after surgery or trauma while they stay in the ICU for more than a week. It also compares results with healthy adults to better understand how critical illness affects nutrition needs.
Petah TikvaAges 18 years+ - NCT03484325Enrolling by invitation
Patient registry for joint replacement and related surgeries
This trial is a “registry,” meaning it collects information from people who choose certain elective joint surgeries. It may help doctors better understand outcomes and safety after procedures like hip and knee operations.
Houston, TexasAges 18–100 - NCT03407833Enrolling by invitation
Study changes in the body after weight, gut, or liver treatment
This study looks at how the body’s insulin-sensitivity (how well your body uses sugar/insulin) and organ function change after certain medical procedures. It may help researchers understand why some people improve after surgery or liver transplant and guide future care.
Nashville, TennesseeAges 18 years+ - NCT03107520RecruitingEarly Phase 1
Ultrasound during hip surgery to check blood flow
This early-phase study tests a special ultrasound with an added contrast medicine (Lumason) during surgery for babies with developmental dysplasia of the hip (DDH). It aims to better see blood flow at the time of surgery, which may help guide and improve care.
Philadelphia, PennsylvaniaAges 4 months–2 years - NCT03193970Recruiting
Study recovery after bladder removal surgery
This trial looks at how patients recover after radical cystectomy, a surgery that removes the bladder for bladder cancer. It will study recovery patterns to help understand what recovery may look like and possibly improve care.
Stanford, CaliforniaAges 18 years+ - NCT03155854Recruiting
Surgery to prevent scarring in trigger finger
This study looks at whether doing a limited surgery in advance can improve outcomes and reduce scarring for people with trigger finger who also have a specific palm cord condition. It may help you heal better if you’ve already tried non-surgical treatment or chose surgery.
Rochester, MinnesotaAges 18 years+ - NCT02743832Recruiting
Personalized surgery planning for early mouth cancer
This study helps doctors plan surgery more individually for early-stage oral (mouth) squamous cell carcinoma. It focuses on using tumor features found during evaluation to guide surgical decisions, aiming to improve treatment accuracy.
Guangzhou, GuangdongAges 20–70 - NCT02598349RecruitingPhase 2
Proton radiation for pancreas cancer that can’t be removed
This trial tests proton radiation for people with pancreas cancer that cannot be fully removed by surgery (or who choose not to have surgery). It may help shrink or control the cancer using a treatment that aims to better target the tumor while limiting dose to nearby organs.
Little Rock, ArkansasAges 18 years+ - NCT02395497RecruitingPhase 2/Phase 3
Penile transplant trial using immune-suppressing medicines
This study tests whether a donated penis can be successfully transplanted using medicines that calm the immune system to prevent rejection. It also looks at safety and recovery of function in men with severe penile loss from injury, cancer surgery, or birth conditions.
Baltimore, MarylandAges 18–69 - NCT02318342Recruiting
Testing blood-thinner treatment for clogged aortic bioprosthetic valves
This study checks whether a blood-thinning medicine can treat problems with a bioprosthetic (man-made tissue) aortic valve. It focuses on valve “clots” that can happen after either a catheter-based or surgery-based valve replacement.
Los Angeles, CaliforniaAges 18 years+ - NCT02107989Recruiting
MRI and brain scans before epilepsy surgery
This study collects noninvasive brain scan data (mainly MRI, sometimes MEG) from people being evaluated for focal epilepsy surgery, and from healthy volunteers. It aims to build reference “normal” brain images and improve how doctors plan and interpret epilepsy surgery evaluations.
Bethesda, MarylandAges 8–120
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.