Clinical trials
Thoracic clinical trials
Below are recruiting thoracic clinical trials, each written for real people, not researchers. We’re tracking 318 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04952480RecruitingPhase 2
Adaptive chest radiation for newly diagnosed small cell lung cancer
This study tests a customized (“adaptive”) way to give radiation to the chest for newly diagnosed small cell lung cancer. It aims to improve how well treatment targets the tumor while safely adjusting to tumor changes during therapy.
Edmonton, AlbertaAges 18 years+ - NCT04990713Recruiting
Compare two pain-blocking methods during lung surgery
This study tests two different ways of numbing the chest to reduce pain during video-assisted lung surgery (VATS). It may help some people have less pain after surgery while still allowing the surgeon to do the operation safely.
London, OntairoAges 18 years+ - NCT05146986Recruiting
RibFix versus usual non-surgical care for broken ribs
This trial compares a rib-fix surgery system (RibFix Blu) to non-surgical treatment for certain broken ribs. It looks at which approach helps people heal better and recover with less ongoing trouble after the injury.
Sydney, New South WalesAges 18 years+ - NCT05170815Recruiting
Spine Device Registry for Adults Getting Commercial Devices
This study is a registry that collects information about adults who use specific, commercially available spine devices. It may help doctors understand how these devices are used in real-world care and what outcomes look like over time.
LyonAges 18 years+ - NCT05227547Recruiting
Study of lung cell changes in smokers and lung disease
This study looks at specific lung cells (called alveolar cells) to understand how smoking and chronic lung disease may change them. You may be invited if you are having lung surgery and can safely take part.
CréteilAges 18 years+ - NCT05267041Recruiting
Lung cancer database study at Lyon hospitals
This study collects information about people who have been treated for lung or chest cancers at Lyon University Hospital. Your data may help researchers better understand these cancers and improve future care.
Pierre-BéniteAges 18 years+ - NCT05281003RecruitingPhase 2
Pembrolizumab plus chemo before surgery for esophageal cancer
This trial tests whether giving pembrolizumab (an immune therapy) plus chemotherapy before surgery can improve outcomes for people with locally advanced, operable esophageal squamous cell carcinoma. It may help shrink the tumor and improve the chance of successful surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05313191Recruiting
Proton therapy for tumors after prior radiation
This study looks at whether a type of proton beam treatment can be given safely and effectively to tumors that have already been treated with radiation before. It may help people whose tumors came back or persisted after earlier radiation, using a specific proton method called pencil beam scanning.
New York, New YorkAges 18 years+ - NCT05351229RecruitingPhase 4
Spinal morphine for pain control after lung surgery
This trial tests whether putting morphine into the spinal area during lung surgery can reduce pain after surgery for people having certain minimally invasive lung operations. It aims to improve comfort and possibly reduce the need for other pain medicines.
Chicago, IllinoisAges 18–80 - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT05369130Recruiting
Predict pain after major aortic surgery
This study tries to understand and predict persistent pain after elective surgery on the thoraco-abdominal aorta (a major blood vessel in the chest and belly). The goal is to learn what factors may help patients have less long-lasting pain after surgery.
LondonAges 18 years+ - NCT05369520Recruiting
Noninvasive spinal stimulation to improve bladder and autonomic function
This trial tests a noninvasive way to stimulate the spinal cord to help the body’s “automatic functions” (like bladder, bowel, and sexual function) after spinal cord injury. If you’ve had a stable, complete spinal cord injury for more than a year, you may be eligible to try this approach and help researchers evaluate recovery.
Vancouver, British ColumbiaAges 19–60 - NCT05375643Recruiting
Get help enrolling in a genomics-based cancer trial
This study helps support people who are from groups less represented in cancer genetics research to get enrolled in genomics-based cancer trials. If you’re starting a new patient visit for an advanced stomach, blood, or lung cancer, this may guide you through options that use your genetic information.
Boston, MassachusettsAges 18 years+ - NCT05406167Recruiting
Tracking quality of life during radiotherapy with a new system
This study collects information about how you feel and how treatment is delivered while you receive radiotherapy using the RefleXion Medical radiotherapy system. It may help doctors improve care and better understand what affects quality of life during treatment.
Duarte, CaliforniaAges Any age - NCT05443841Recruiting
Pleural lavage test to guide surgery in resectable esophageal cancer
This trial studies whether washing fluid from around the lungs (pleural lavage) can show cancer cells and help predict outcomes for people with operable esophageal cancer. It may add useful information before surgery to support better treatment decisions.
Hefei, AnhuiAges Any age - NCT05479305Recruiting
Stent placement for thoracic aorta problems in urgent high-risk patients
This trial studies a new type of stent graft placed in the chest aorta (from the aortic arch into the descending part) to treat aneurysms or dissections in people who are too high-risk for open surgery. It may help by offering a faster, less invasive repair when waiting for a custom stent would be unsafe.
BrestAges 18 years+ - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT05657990RecruitingEarly Phase 1
Preventing trouble peeing after chest cancer surgery
This early-phase trial tests whether taking tamsulosin-like treatment around the time of chest cancer surgery can prevent urinary retention, when people cannot pee after surgery. It may help lower the chance of needing extra catheter care after the operation.
Brick, New JerseyAges 55 years+ - NCT05693363Recruiting
Scan lung tissue with a PET-CT during thoracic surgery
This study tests whether a special imaging scan using a radioactive sugar (18F-FDG) can help doctors better examine lung cancer tissue during thoracic surgery. You may be offered the scan around the time of your operation to help researchers learn how well it works.
GhentAges 18 years+ - NCT05906134RecruitingPhase 1/Phase 2
Pain control plan after minimally invasive esophagus surgery
This trial tests a pain-control method (using an epidural/nerve pain-block through the back, called neuraxial anesthesia) for people having minimally invasive esophagus removal surgery. It may help reduce pain after surgery and improve comfort during recovery.
Seattle, WashingtonAges 18 years+ - NCT05931783Recruiting
Compare two ways to use an artery during heart bypass
This study compares two surgical techniques for heart bypass: using the left internal thoracic artery in one specific way versus another. It may help improve how well the bypass works in people who need bypass surgery for multiple blocked heart arteries.
GrazAges 18–80 - NCT05990946Recruiting
Smartphone monitoring after lung cancer surgery
This trial tests if using a smartphone app to track your symptoms after minimally invasive lung cancer surgery can help you stick to your recovery exercises. It aims to improve your recovery by keeping you connected with your care team.
Zhongshan, GuangdongAges 18–75 - NCT06056336RecruitingPhase 2
Perioperative tislelizumab plus chemo for esophageal cancer
This trial tests whether giving tislelizumab (an immunotherapy) along with chemotherapy before and after surgery can help people with a type of esophageal cancer called squamous cell carcinoma. The goal is to see if this combination improves outcomes for patients whose cancer is in the chest and can be removed with surgery.
Shanghai, Shanghai MunicipalityAges 18–75
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Common questions
- Are there clinical trials for thoracic?
- Yes. Clin2 currently lists 318 recruiting thoracic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.