Clinical trials
Thrombolysis clinical trials
Below are recruiting thrombolysis clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06143969Recruiting
Ultrasound-guided clot-dissolving treatment for intermediate-high risk pulmonary embolism
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
Milan, ItaliaAges 18 years+ - NCT04620642Recruiting
Registry for adults treated with clot-busting or clot removal
This trial is a registry that collects information from adults who were hospitalized for an ischemic stroke and received either clot-busting medicine or a procedure to remove the clot. It may help doctors better understand stroke treatments and outcomes.
LyonAges 18 years+ - NCT05922540Recruiting
Study of ischemic stroke to improve patient care
This study looks at people who have had an ischemic stroke (a type caused by a blocked blood vessel). It is collecting information over time to better understand care needs and follow-up after stroke.
HunanAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT07785492Recruiting
AI-assisted care for acute ischemic stroke
This trial tests whether an artificial intelligence system can help doctors make better treatment decisions for people who have had an acute ischemic stroke within the last 24 hours. The goal is to see if this AI support improves outcomes compared to standard care.
Changsha, HunanAges 18 years+ - NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07665320Recruiting
Monitoring DVT treatment with a new skin sensor
This study tests a new, non-invasive skin sensor that uses electrical currents to see how well clot-busting medication is working in people with deep vein thrombosis (a blood clot in the leg). The goal is to make monitoring easier and more comfortable.
TampereAges 18 years+ - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07526987RecruitingPhase 3
Minocycline to Help Recovery After Acute Stroke Treatment
This study tests whether an antibiotic called minocycline, given alongside standard stroke treatment (clot-busting medication), can help reduce brain damage and improve recovery. You would receive minocycline around the time of your clot-busting treatment.
Liaocheng, ShandongAges 18–80 - NCT07530588Recruiting
Remote CT imaging for fast stroke treatment decisions
This study tests whether CT scans done remotely (by doctors at a distance) can help stroke patients receive clot-busting treatment faster. Stroke treatment works best when given quickly, and this approach aims to speed up diagnosis in areas far from major hospitals.
SandnessjøenAges 18 years+ - NCT05378490Recruiting
Study of stroke types and thrombolysis treatment
This study includes people who have had certain kinds of sudden brain blood-flow problems (like an ischemic stroke, bleeding in the brain, or a brief warning episode) or conditions that look similar. It looks at how treatment such as clot-busting medicine (thrombolysis) fits for these situations.
LørenskogAges 18 years+ - NCT07419997Recruiting
Observational study on clot-busting drugs beyond the usual window
This study looks at patients who received a clot-busting drug (intravenous thrombolysis) for their stroke 4.5 to 24 hours after symptoms started. It aims to see how well this works and what happens to them, using data that has already been collected.
BeijingAges 18 years+ - NCT07375966RecruitingPhase 2
Repeated clot-busting drug for stroke with large vessel block
This trial tests if giving a second dose of the clot-busting drug tenecteplase can help people whose stroke symptoms don't improve after the first dose, when a large or medium artery in the brain is still blocked. It may be an option for patients who cannot have a mechanical clot removal procedure.
Shenyang, LiaoningAges 18–80 - NCT07375953RecruitingPhase 2
Repeated clot-busting drug for stroke within 3 hours
This trial tests if giving a second dose of a clot-busting drug (tenecteplase) helps people who had a stroke and didn't improve much after the first dose. You must receive the second dose within 4.5 hours of your stroke symptoms starting.
Shenyang, None SelectedAges 18–80 - NCT07318948Recruiting
Blood pressure control in stroke patients receiving thrombolysis
This trial tests a strategy for managing high blood pressure in people having an acute ischemic stroke who are about to receive clot-busting medication. It aims to see if carefully lowering blood pressure within a specific range improves outcomes.
Chengdu, SichuanAges 18 years+ - NCT07290751RecruitingPhase 4
Adding tirofiban to clot-busting for stroke patients
This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07203625RecruitingPhase 4
Tenecteplase before transfer for basilar artery stroke
This trial tests if a clot-busting drug called Tenecteplase helps people with a severe type of stroke in the back of the brain (basilar artery occlusion) when given 4.5 to 24 hours after symptoms start. Patients will then be moved to a hospital that can remove the clot. The goal is to see if the drug improves recovery.
BeijingAges 18 years+ - NCT07160491Recruiting
Early clot-dissolving treatment guided by AI app for heart attacks
This trial tests whether an AI-powered app can help doctors give clot-busting medicine earlier to people having a severe heart attack (STEMI) when immediate angioplasty isn't possible. If you can't get a procedure within 2 hours, this treatment might be an option.
Shenyang, LiaoningAges 18–80
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Common questions
- Are there clinical trials for thrombolysis?
- Yes. Clin2 currently lists 60 recruiting thrombolysis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thrombolysis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thrombolysis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.