Clinical trials
Thrombolysis clinical trials
Below are recruiting thrombolysis clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07452991Recruiting
Ultrasound-guided clot-busting for moderate-risk pulmonary embolism
This trial tests a procedure that uses ultrasound to guide a catheter that delivers clot-dissolving medicine directly to a blood clot in the lungs. It is for people who have a pulmonary embolism that causes some heart strain but who are not in shock.
MoscowAges 18 years+ - NCT06571149RecruitingPhase 4
Blood thinners and clot-busting drugs for stroke
This trial tests whether giving a clot-dissolving medicine (alteplase or tenecteplase) is safe and effective for people who have had a stroke and are taking a blood thinner (DOAC) like apixaban or rivaroxaban. It aims to see if this treatment can still be given within a few hours of the stroke.
EisenstadtAges 18 years+ - NCT03881345Recruiting
Registry for blood clots in legs or lungs
This registry collects information from people who have a blood clot in a leg or a clot in the lung. It helps researchers understand how these conditions are treated in real life.
Moscow, MoscowAges 18 years+ - NCT04620642Recruiting
Registry for adults treated with clot-busting or clot removal
This trial is a registry that collects information from adults who were hospitalized for an ischemic stroke and received either clot-busting medicine or a procedure to remove the clot. It may help doctors better understand stroke treatments and outcomes.
LyonAges 18 years+ - NCT04624295RecruitingPhase 4
Aspirin soon after certain bleeding stroke, after clot-busting therapy
This trial studies whether starting aspirin early is safe and helpful for people who, after clot-busting treatment for an ischemic stroke, develop a specific type of small brain bleeding called hemorrhagic infarction. You might benefit if your scan later shows this pattern of bleeding and you are not able to take blood-thinners or aspirin is safe for you.
HangzhouAges Any age - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05372718RecruitingPhase 3
Clot-busting drug versus surgery for sudden blocked leg arteries
This trial compares a clot-busting medicine (staphylokinase) against surgery in people with sudden, dangerous reduced blood flow to a leg. It may help find a safer or more effective way to restore circulation and prevent limb complications.
Kursk, Kursl RegionAges 18 years+ - NCT05378490Recruiting
Study of stroke types and thrombolysis treatment
This study includes people who have had certain kinds of sudden brain blood-flow problems (like an ischemic stroke, bleeding in the brain, or a brief warning episode) or conditions that look similar. It looks at how treatment such as clot-busting medicine (thrombolysis) fits for these situations.
LørenskogAges 18 years+ - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT05741905Recruiting
Levofloxacin antibiotic with IV clot-busting for acute stroke
This trial tests whether adding the antibiotic levofloxacin to standard IV clot-busting treatment is safe and improves outcomes after an acute ischemic stroke. It may help by reducing complications related to infection or inflammation, but you must meet specific heart, liver, kidney, and medication-safety rules.
Changchun, JilinAges 18–75 - NCT05922540Recruiting
Study of ischemic stroke to improve patient care
This study looks at people who have had an ischemic stroke (a type caused by a blocked blood vessel). It is collecting information over time to better understand care needs and follow-up after stroke.
HunanAges 18 years+ - NCT06045156Recruiting
Tirofiban after clot-busting for stroke
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
Changchun, JilinAges 18 years+ - NCT06157502RecruitingPhase 3
Shuxuening with clot-busting treatment for ischemic stroke
This trial tests if adding the herbal injection Shuxuening to standard clot-busting treatment improves recovery for people having an ischemic stroke. It is for adults within 6 hours of symptom onset who are already receiving a clot-dissolving medication.
Beijing, Beijing MunicipalityAges 18–100 - NCT06320431RecruitingPhase 3
Clot-busting drug for disabling stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for people having a disabling ischemic stroke (a clot blocking blood flow to the brain). It aims to see if the drug can help improve recovery when given within 4.5 hours of symptoms starting.
Sydney, BarangarooAges 18 years+ - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06548971RecruitingPhase 3
Early antiplatelet after clot-busting for stroke (TREND-IVT)
This trial tests whether giving an antiplatelet medicine (like aspirin) early—within 3 hours of a clot-busting drug—can help prevent another stroke without causing bleeding. It is for people who still have moderate to severe stroke symptoms after the clot-buster and do not have a large artery blockage.
Bengbu, AnhuiAges 18 years+ - NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06654453Recruiting
Clot removal during heart catheterization after clot-busting medicine
This study tests whether removing a clot with a special suction device during a heart catheterization helps people who already received a clot-busting medicine for a severe heart attack. It may improve blood flow and reduce damage to the heart muscle.
Changsha, HunanAges 18 years+ - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT07092709RecruitingPhase 3
Tenecteplase for stroke patients who recently took blood thinners
This trial tests if the clot-busting drug tenecteplase is safe and effective for people having an ischemic stroke who have recently taken blood thinners (DOACs). If you qualify, you may receive either tenecteplase or a placebo within 24 hours of your last known well time.
Guangzhou, GuangdongAges 18 years+ - NCT07094763Recruiting
Tenecteplase for posterior stroke 4.5-24 hours after onset
This trial tests a clot-busting drug called tenecteplase for people who had a stroke affecting the back part of the brain (posterior circulation). It may be an option if you can get treatment between 4.5 and 24 hours after symptoms started.
HefeiAges 18–100
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Common questions
- Are there clinical trials for thrombolysis?
- Yes. Clin2 currently lists 60 recruiting thrombolysis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thrombolysis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thrombolysis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.