Clinical trials
Thrombolysis clinical trials
Below are recruiting thrombolysis clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07187687Recruiting
Early minimally invasive clot removal for brain hemorrhage
This study tests if removing a large brain clot early using a small tube and clot-dissolving medicine can improve recovery after a hemorrhagic stroke. It is for people with a moderate to large bleed who can start treatment within 12 hours of symptoms.
Guangdong, YuexiuAges 18 years+ - NCT06198816Recruiting
Ultrasound and balloon treatment for old leg clots
This study tests a new way to treat long-standing blood clots in the leg using ultrasound waves and a balloon procedure. It aims to improve blood flow and reduce symptoms like swelling and pain for people who haven't gotten better with standard treatments.
Milan, ItalyAges 18–75 - NCT06833827Recruiting
Clot removal vs clot-busting drugs for severe lung clots
This study compares two ways to treat a large blood clot in the lungs that is causing life-threatening symptoms. One method uses a device to remove the clot, the other uses medicine to dissolve it.
Leiden, South HollandAges 18 years+ - NCT06472518RecruitingPhase 4
Clot-busting treatment plus blood thinners for severe leg clots
This trial tests whether combining a clot-busting procedure (pharmaco-mechanical thrombolysis) with standard blood thinners works better than blood thinners alone for people with severe, recently formed deep vein clots in the upper leg.
NantesAges 18 years+ - NCT06487052Recruiting
Catheter-based clot-dissolving drug for intermediate-high risk pulmonary embolism
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
Saint PetersburgAges 18 years+ - NCT07294209RecruitingPhase 4
Low-dose tenecteplase for older adults with stroke
This trial tests a lower dose of the clot-busting drug tenecteplase in people aged 70 and older who have had an ischemic stroke. It aims to see if this treatment is safe and effective for older patients when given within 4.5 hours of symptoms starting.
Chongqing, Chongqing MunicipalityAges 70 years+ - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT07047326Recruiting
Urokinase for acute ischemic stroke within 6 hours
This trial tests whether the clot-busting drug urokinase can help people who have had an ischemic stroke (a stroke caused by a blood clot). The goal is to dissolve the clot and improve recovery, as long as treatment starts within 6 hours of the first symptoms.
Beijing, Beijing MunicipalityAges 18–80 - NCT05347732Recruiting
Finds why heart clot treatment may not work
This study looks at people with a specific type of heart attack who received clot-busting treatment before reaching the hospital. It aims to figure out what predicts why the treatment might fail, which could help improve care in the future.
OsloAges 18 years+ - NCT05554588Recruiting
Thrombus-finding treatments for heart attack during angioplasty
This trial compares two ways to remove or break up a blood clot during emergency heart artery opening (primary PCI) for a specific type of heart attack (STEMI). It may help patients with a high clot burden by testing whether one approach works better than the other to improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06131385Recruiting
Tracking IV clot-busting treatment for stroke in China
This study is tracking patients in southwestern China who have had an acute ischemic stroke and received a clot-busting medicine through an IV. It aims to learn more about how well this treatment works and how it is used in real-world settings.
LuzhouAges Any age - NCT06143969Recruiting
Ultrasound-guided clot-dissolving treatment for intermediate-high risk pulmonary embolism
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
Milan, ItaliaAges 18 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT06727006Recruiting
Rescue stenting and clot-dissolving medicine for severe stroke
This trial tests whether using a stent plus a clot-dissolving drug can improve outcomes for people with a large-vessel stroke who are having a procedure to remove the clot. It is designed for patients who can receive treatment within 24 hours of their first symptoms.
Bergamo, ItalyAges 18 years+ - NCT06749834RecruitingPhase 3
Clot-busting drug after stroke in people on newer blood thinners
This trial tests whether a clot-busting medication given through a vein (intravenous thrombolysis) can safely treat acute ischemic stroke within 24 hours in people who have taken a newer oral blood thinner (NOAC) within the last 4 to 48 hours.
Hangzhou, ZhejiangAges 18 years+ - NCT06878066RecruitingPhase 3
Clot-busting treatment after stroke while on Factor Xa inhibitor
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Bærum, GjettumAges 18 years+ - NCT07119021RecruitingPhase 4
Ultra-early stroke treatment with neuroprotection and clot removal
This trial tests a new approach for treating acute ischemic stroke within 4.5 hours of symptoms starting. It combines a special mobile stroke unit that delivers early brain-protecting medicine with standard clot-busting or clot-removal procedures, to see if this can improve recovery.
BeijingAges 18–80 - NCT07137832RecruitingPhase 3
Testing clot-busting drug during stroke treatment for medium vessel blockages
This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
Guangzhou, GuangdongAges 18 years+ - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT07208097Recruiting
Brain bleed clot dissolving with tNK for stroke recovery
This trial tests a clot-busting drug called tenecteplase given directly into the brain bleed through a thin tube. It may help reduce damage and improve recovery for people with a certain type of brain hemorrhage.
Suzhou, AnhuiAges 18–80 - NCT06453876RecruitingPhase 3
Comparing clot removal, low-dose clot dissolver, and heparin for high-risk lung clot
This trial compares three treatments for an intermediate-high risk pulmonary embolism: a minimally invasive clot removal procedure (embolectomy), a low-dose clot-dissolving medication, or standard blood thinning (heparin). The goal is to see which approach works best to prevent worsening while reducing bleeding risks.
CopenhagenAges 18 years+ - NCT07279259RecruitingPhase 2
Blood pressure management after stroke clot-dissolving treatment
This trial tests how managing high blood pressure during clot-dissolving treatment for acute ischemic stroke affects recovery. It is for patients who have high blood pressure at the start of treatment.
ShanghaiAges 18–80 - NCT07302854RecruitingPhase 2/Phase 3
Clot-busting medicine for medium vessel strokes
This trial tests a new clot-busting medicine called tenecteplase, given directly into the blood vessel in the brain, to treat strokes caused by a blockage in a medium-sized artery. The goal is to see if it can help restore blood flow and reduce disability, especially for patients who can be treated within 24 hours of stroke onset.
Wuhan, HubeiAges 18 years+
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Common questions
- Are there clinical trials for thrombolysis?
- Yes. Clin2 currently lists 60 recruiting thrombolysis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thrombolysis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thrombolysis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.