Clinical trials
Thyroid Nodule clinical trials
Below are recruiting thyroid nodule clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05726981Recruiting
Ultrasound check of benign thyroid nodules 3 years after ablation
This study follows people with a benign (non-cancer) thyroid nodule about 3 years after they had a heat-based ablation, using ultrasound and a sample for cytology (cell/tissue review). It aims to see what the nodule looks like long-term and how well these checks track changes.
ParisAges 18 years+ - NCT06779747Recruiting
Comparing thyroid treatment approaches over time
This study looks back at medical records and follows new patients to understand which thyroid treatments work best for different conditions. It includes people with an underactive or overactive thyroid, thyroid nodules, or thyroid cancer.
Bologna, BolognaAges 18 years+ - NCT05189314Recruiting
Study of life quality changes with benign thyroid nodules
This study looks at how benign (non-cancer) thyroid nodules affect people’s day-to-day life and health outcomes. It may help doctors better understand what changes matter most to patients.
New York, New YorkAges 18 years+ - NCT06738888Recruiting
Better predicting easy thyroid removal through mouth or under chin
This study compares two approaches for thyroid removal surgery—one through the mouth and one under the chin—to find which is easier to perform. It is for people with thyroid nodules or early thyroid cancer that hasn't spread.
ShanghaiAges Any age - NCT04666103Recruiting
Study of neck anatomy in thyroid surgery
This study looks at how the structures in the neck affect thyroid surgery outcomes. You may be asked about your diagnosis and pre-surgery neck imaging to better understand surgical safety for people with certain thyroid conditions.
Wuhan, HubeiAges 18–75 - NCT07488325Recruiting
Using AI to better understand unclear thyroid biopsy results
This study uses artificial intelligence (AI) to look at ultrasound images and cell samples from thyroid nodules that had an unclear biopsy result. The goal is to see if AI can better tell which nodules are cancerous, helping avoid unnecessary surgery in the future.
Guangzhou, GuangzhouAges 18–80 - NCT07360587Recruiting
Thyroid artery embolization for large goiters
This trial tests a non-surgical procedure called thyroid artery embolization (TAE) to shrink a goiter that is pressing on your windpipe or throat. It may help if you cannot have surgery or prefer an alternative.
Sherbrooke, QuebecAges 18 years+ - NCT06868459Enrolling by invitation
Study of PED-TAE treatment for thyroid disease
This study tracks people who have already received a new type of thyroid treatment called PED-TAE (pressure-enabled embolization) using the TriNav system. It aims to see how well this procedure works for various thyroid conditions, including overactive thyroid, large goiters, and benign nodules causing symptoms.
Sarasota, FloridaAges 18–89 - NCT05229341Recruiting
Testing DNA “methylation” to evaluate thyroid nodule samples
This study looks at patient tissue from needle biopsies to see if DNA “methylation” patterns can help diagnose and guide treatment for thyroid nodules. You might benefit by helping improve how these nodules are evaluated, using information from your biopsy sample and medical data.
Duarte, CaliforniaAges 18 years+ - NCT06984991Recruiting
Why some thyroid biopsy samples are hard to evaluate quickly
This trial looks at what makes it harder to quickly tell if a thyroid nodule sample is good enough for diagnosis during your biopsy. It may help doctors improve the procedure for people with suspicious nodules.
Asyut, Asyut GovernorateAges 18 years+ - NCT07287176Recruiting
Treating benign thyroid nodules with a new device
This trial tests a new device that uses nanosecond electrical pulses to treat benign thyroid nodules. It may be an option if you have a benign nodule causing symptoms like discomfort or anxiety, and you're looking for a non-surgical treatment.
Sarasota, FloridaAges 22–80 - NCT07140757Recruiting
Radiofrequency ablation for thyroid nodules and low-risk cancer
This trial tests radiofrequency ablation (a heat-based treatment) for people with non-cancerous or suspicious thyroid nodules, or small thyroid cancers. It may be an option if you are not a candidate for or choose not to have surgery.
Houston, TexasAges 18 years+ - NCT06849284Recruiting
Predicting thyroid nodule results with a new test
This study tests a new tool (ThyroidPrint) to see if it can accurately predict whether a thyroid nodule with unclear biopsy results is benign or malignant. The goal is to help doctors and patients decide on surgery more confidently.
Truro, CornwallAges 18 years+ - NCT06207188Recruiting
Using sound waves to tell thyroid lumps apart
This study uses a special ultrasound technique to look at thyroid nodules and lumps in the neck. The goal is to tell the difference between harmless lumps and cancer, so you may get a clearer answer without extra procedures.
Scottsdale, ArizonaAges 8 years+ - NCT07041307Recruiting
Study of blood flow in thyroid nodules before surgery
This trial uses a special imaging technique to look at the tiny blood vessels inside thyroid nodules before they are removed. It may help doctors understand which nodules are cancerous.
CopenhagenAges 18 years+ - NCT07102264Recruiting
Ultrasound test for thyroid stiffness before surgery
This study tests a new, non-invasive ultrasound method to measure how compressible (squishy) your thyroid gland is, before you have surgery to remove it. The goal is to see if this safe, painless measurement can help surgeons plan better.
BernAges 18 years+ - NCT05903196Recruiting
Radiofrequency treatment for non-cancer thyroid lumps in LatinX adults
This study looks at radiofrequency ablation, a heat-based procedure, to shrink a benign (non-cancer) thyroid nodule in adults who identify as LatinX. It may help reduce symptoms from the lump while tracking safety and results.
New York, New YorkAges 18–90 - NCT06539702Recruiting
Blood tests and BRAF for thyroid nodules
This trial studies whether routine blood counts and a BRAF genetic test can help predict cancer in thyroid nodules that were found to be suspicious (Bethesda 3 category) before surgery. The goal is to better understand which nodules are cancerous.
IstanbulAges 18–75 - NCT07270237Recruiting
New ultrasound imaging for pancreas and thyroid
This study tests new ultrasound methods to better see the pancreas and thyroid. It includes people at high risk for pancreatic cancer, those with pancreatic cancer, those with a thyroid nodule, and healthy volunteers.
Basking Ridge, New JerseyAges 18 years+ - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT06829043Enrolling by invitation
PET scan for uncertain thyroid nodules
This study uses a special PET scan (18F-FDG PET/CT) to get a clearer picture of thyroid nodules with uncertain biopsy results. The goal is to help doctors decide whether surgery is needed.
Bologna, ItalyAges 18 years+ - NCT07033572Recruiting
Hybrid scope surgery and ablation for both sides of thyroid cancer
This study tests a combined approach—removing the main thyroid cancer with a tiny camera (endoscope) and using targeted heat to destroy a small nodule on the opposite side. It aims to treat both sides of the thyroid at once with less scarring and faster recovery.
Fuzhou, FujianAges 18–65
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Common questions
- Are there clinical trials for thyroid nodule?
- Yes. Clin2 currently lists 46 recruiting thyroid nodule studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid nodule trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid nodule trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.